Members

YBRI hosts over 90 principal investigators covering a range of disciplines, addressing biomedical challenges at regional, national and global scales.

Below you can find academics according to their research interests. Information relating to YBRI leadership, governance and facilitation can be found on the YBRI Governance and Reporting page.

Name	Research interests	Disease Pillars	Cross-cutting Themes
Jon Agirre Chemistry jon.agirre@york.ac.uk	Structural biology; Protein glycosylation; Post-translational modifications; Method development; Alphafold		Molecular Mechanisms and Tools
Luke Alphey Biology luke.alphey@york.ac.uk	Synthetic biology; Genetics; Vectors; Arboviruses; Translation	Infection
Joshua Ang Biology joshua.ang@york.ac.uk	engineering biology; mosquito; arbovirus	Infection
Fred Antson Chemistry fred.antson@york.ac.uk	Structural Biology; Cryo-EM; Protein-nucleic acid interactions; Virus assembly; Herpesviruses	Infection	Molecular Mechanisms and Tools
Kofi Appiah Computer Science kofi.appiah@york.ac.uk	Computer Vision; Embedded Systems; Machine Learning; Deep Learning; Medical Imaging	Cancer	Biomedical Healthcare Technologies
Nicola Baker Biology nicola.baker@york.ac.uk	Leishmania; Parasitology; Environmental sensing; Kinase; Sand fly	Infection
Simon Baker Biology simon.baker@york.ac.uk	Epithelial; Carcinogenesis; Transcriptomics; Genomics; Mutational signatures	Cancer, Infection	Immunity
Daniela Barillà Biology daniela.barilla@york.ac.uk	Genome segregation; antibiotic resistance; chromosome & plasmid biology; DNA-protein interactions.	Infection	Molecular Mechanisms and Tools
Gavin Barlow HYMS gavin.barlow@york.ac.uk	Infection; Antibiotics; Antimicrobials; Biomarkers; Prognosis	Infection	Biomedical Healthcare Technologies
Jillian Barlow Biology jillian.barlow@york.ac.uk	Immunology; Innate lymphoid cells; Mouse models; Blood cancer; NK cells	Infection, Cancer	Immunity
Heidi Baseler HYMS heidi.baseler@york.ac.uk	Vision; Neuroimaging; Neuroprotection; Blindness; Deafness	Brain Health	Biomedical Healthcare Technologies
Christoph Baumann Biology christoph.baumann@york.ac.uk	Microbial biophysics; Single-molecule fluorescence imaging; Membrane Dynamics; Bacterial cell surface biology; Chemical biology	Infection	Molecular Mechanisms and Tools, Immunity
Oliver Bayfield Biology oliver.bayfield@york.ac.uk	CryoEM; viruses; gut microbiome; bacteriophage; ESKAPE pathogens	Infection	Molecular Mechanisms and Tools, Biomedical Healthcare Technologies
Joanne Berry YBRI support			Biomedical Healthcare Technologies
Jamie Blaza Chemistry jamie.blaza@york.ac.uk	CryoEM; Electron-tomography; Bacteria; Bioenergetics; Pathogens	Infection	Molecular Mechanisms and Tools
Dave Boucher Biology dave.boucher@york.ac.uk	Cell death; Protease Signalling; Innate Immunity; Biochemistry; Cell Signalling	Infection, Cancer	Immunity, Molecular Mechanisms and Tools
Will Brackenbury Biology william.brackenbury@york.ac.uk	Brain tumours; Breast cancer; Ion channels; Metastasis; Microglia	Cancer, Brain Health	Immunity, Biomedical Healthcare Technologies
Katherine Bridge Biology katherine.bridge@york.ac.uk	Cancer cell biology; Transcription factor biology; Haematopoietic stem cells; Hypoxia/HIFs	Cancer	Biomedical Healthcare Technologies
Nia Bryant Biology nia.bryant@york.ac.uk	Diabetes (Type-2); Membrane traffic; SNARE proteins; Insulin action; Neutropenia		Biomedical Healthcare Technologies
Scott Cairney Psychology scott.cairney@york.ac.uk	Sleep; Memory; Emotion; Mental Health; Polysomnography	Brain Health	Biomedical Healthcare Technologies
Alan Cartmell Biology alan.cartmell@york.ac.uk	Microbiology; Enzymology; structural biology; glycobiology	Brain Health	Molecular Mechanisms and Tools, Biomedical Healthcare Technologies, Immunity
Mathieu Cayla Biology mathieu.cayla@york.ac.uk	Parasitology; Trypanosome; Signalling; Autophagy; Differentiation	Infection	Molecular Mechanisms and Tools
Rebecca Chalkley RIKE support rebecca.chalkley@york.ac.uk
Manish Chauhan School of PET manish.chauhan@york.ac.uk	Soft robotics (for biomedical applications); Microbiology; Robot-assisted medical devices; Optical fibre technology (spectroscopy); Medical diagnostics and therapeutic intervention	Cancer, Infection, Brain Health	Biomedical Healthcare Technologies
Sangeeta Chawla Biology sangeeta.chawla@york.ac.uk	Synaptic-plasticity; Transcription; Circadian; Ca2+ signalling; Oxidative stress	Brain Health, Cancer, Infection	Immunity
Victor Chechik Chemistry victor.chechik@york.ac.uk	Magnetic nanoparticles; Nanoparticle drug delivery; Reactive oxygen species; Free radicals; EPR spectroscopy		Biomedical Healthcare Technologies
Han-Jou Chen Biology han-jou.chen@york.ac.uk	Neurodegeneration; Amyotrophic Lateral Sclerosis (ASL); Alzheimer’s Disease; Frontotemporal Dementia; Parkinson’s Disease	Brain Health	Biomedical Healthcare Technologies
James Chong Biology james.chong@york.ac.uk	Gut microbiome; Nanopore sequencing; Growth of anaerobes	Brain Health, Infection	Biomedical Healthcare Technologies
Anastasia Conti Biology anastasia.conti@york.ac.uk	Normal and malignant haematopoiesis	Cancer	Biomedical Healthcare Technologies
Dawn Coverley Biology dawn.coverley@york.ac.uk	Cell cycle; Nuclear architecture; Early detection of cancer; Technology transfer	Cancer	Biomedical Healthcare Technologies
Cecile Crosnier Biology cecile.crosnier@york.ac.uk	Schistosoma; Recombinant proteins; Immunomodulation; Protein interactions; Parasitology	Infection	Immunity
Alyssa Cull Biology alyssa.cull@york.ac.uk	Blood cancer; immunology; macrophages; clonal haematopoiesis; mutation profiling	Cancer	Immunity
Helen Davies Environment & Geography helen.davies@york.ac.uk	Asthma triggers; In-vitro lung cell/gas exposure experiments; Asthma alarmin expression; Lung Chemistry Modelling; Indoor Air Chemistry Modelling		Immunity, Molecular Mechanisms and Tools
Aditi Dey HYMS aditi.dey@york.ac.uk		Cancer, Infection	Immunity, Biomedical Healthcare Technologies
Anne Duhme-Klair Chemistry anne.duhme-klair@york.ac.uk	Gene therapy	Infection	Molecular Mechanisms and Tools, Biomedical Healthcare Technologies
Peter Ellison School of PET peter.ellison@york.ac.uk	Bionics; medical devices; medical informatics; decision support tools		Biomedical Healthcare Technologies
Gareth Evans Biology gareth.evans@york.ac.uk	Neuronal signalling; Neuronal development; Neuroblastoma; Kinase biochemistry	Brain Health	Molecular Mechanisms and Tools
Karla Evans Psychology karla.evans@york.ac.uk	Visual awareness; Visual neuroscience; Perceptual expertise in radiology; Visual long term memory	Brain Health, Cancer	Biomedical Healthcare Technologies, Molecular Mechanisms and Tools
Joana R. C. Faria Biology joana.correiafaria@york.ac.uk	Gene expression; Nuclear-architecture; Microscopy; Proteomics; Next-generation-sequencing	Infection	Molecular Mechanisms and Tools, Immunity
Martin Fascione Chemistry martin.fascione@york.ac.uk	Chemical biology; Glycosylation; Protein post-translational modifications; Protein bioconjugation; Organic synthesis	Cancer, Infection	Molecular Mechanisms and Tools, Biomedical Healthcare Technologies
Adele Fielding HYMS adele.fielding@york.ac.uk	Acute lymphoblastic leukaemia (ALL); microenvironment; cancer-associated fibroblasts; clinical trials; biobanking	Cancer	Immunity, Biomedical Healthcare Technologies
Paul Fogg Biology paul.fogg@york.ac.uk	Antibiotic resistance; Antimicrobial Resistance (AMR); Evolution; Horizontal gene transfer; Virology; Microbiology	Infection	Molecular Mechanisms and Tools, Biomedical Healthcare Technologies
Fiona Frame RIKE support			Biomedical Healthcare Technologies
Angelo Frei Chemistry angelo.frei@york.ac.uk	Telomere biology	Infection	Molecular Mechanisms and Tools
Richard Gale HYMS richard.gale@york.ac.uk	Ophthalmology; Medical Retina; Neuroimaging; Macular Degeneration; Eye Disease	Brain Health	Biomedical Healthcare Technologies, Immunity, Molecular Mechanisms and Tools
Gareth Gaskell Psychology gareth.gaskell@york.ac.uk	Sleep; Memory consolidation; Polysomnography; Development; Language	Brain Health	Biomedical Healthcare Technologies
Paul Genever Biology paul.genever@york.ac.uk	Mesenchymal stem/stromal cells; Bone marrow; Skeletal biology; Regenerative medicine; Cell and molecular		Biomedical Healthcare Technologies, Immunity
Allison Green HYMS allison.green@york.ac.uk	Developmental cognitive neuroscience; Numeracy development; Functions of the parietal lobe; Dyscalculia; Dyslexia		Immunity
William Grey Biology william.grey@york.ac.uk	Autoimmunity; Type 1 Diabetes; Thymic B cells; Immune system ageing; Preclinical and clinical models of disease	Cancer	Biomedical Healthcare Technologies, Immunity
Silke Göbel Psychology silke.goebel@york.ac.uk	Stem Cells; Proteostasis; Haematopoiesis; Leukaemia; Cancer	Brain Health
Ines Hahn Biology ines.hahn@york.ac.uk	Neurodegeneration; Neurodevelopmental Disorders; Cytoskeleton; Microtubule Dynamics; Drosophila primary neurons	Brain Health, Cancer	Biomedical Healthcare Technologies, Molecular Mechanisms and Tools
Noémie Hamilton Biology noemie.hamilton@york.ac.uk	Translational Neuroscience; Neurodegeneration; Immunology; Zebrafish in vivo models; Live imaging	Brain Health	Immunity, Biomedical Healthcare Technologies, Molecular Mechanisms and Tools
Yvette Hancock School of PET y.hancock@york.ac.uk	Label-free methods; Biomolecular stratification; Biomarkers; Clinical translation; Raman spectroscopy	Cancer
Michelle Hawkins Biology michelle.hawkins@york.ac.uk	Bacteria; DNA replication; Helicases; Replication termination; Biochemistry	Infection	Molecular Mechanisms and Tools
Lisa Henderson Psychology lisa-marie.henderson@york.ac.uk	Development; Language; Disorders; Autism; Sleep	Brain Health, Cancer	Biomedical Healthcare Technologies, Molecular Mechanisms and Tools
James Hewitson Biology james.hewitson@york.ac.uk	Immunology; Parasitology; Immune regulation; Vaccine; Macrophage	Infection	Immunity
Stuart Higgins School of PET stuart.higgins@york.ac.uk	Bioelectronics; biomaterials; bioelectricity; cell interfaces; bioengineering	Cancer	Biomedical Healthcare Technologies
Chris Hill Biology chris.hill@york.ac.uk	Structural biology; RNA biology; Viruses; Gene expression; Translational control	Infection	Molecular Mechanisms and Tools
Ian Hitchcock Biology ian.hitchcock@york.ac.uk	Haematology; Cancer; Cytokine signalling; Haematopoietic stem cells; Infection	Cancer, Infection	Molecular Mechanisms and Tools
Andrew Holding Biology andrew.holding@york.ac.uk	DNA damage response	Cancer	Molecular Mechanisms and Tools, Immunity
Aidan Horner Psychology aidan.horner@york.ac.uk	Memory; Dementia; Hippocampus; fMRI; MEG	Brain Health	Biomedical Healthcare Technologies
Debra Howell Health Sciences debra.howell@york.ac.uk		Cancer
Zhihong Huang School of PET	Functional Ultrasound imaging; Therapeutic ultrasound; Optical Coherent Tomography; Elastography; Tissue mimicking material fabrication and characterisation; Acoustic measurements; Simulation		Biomedical Healthcare Technologies
Neil Hunt Chemistry neil.hunt@york.ac.uk	Ultrafast spectroscopy; Biomolecular interactions; Protein-drug binding; Biofluid analysis		Biomedical Healthcare Technologies, Molecular Mechanisms and Tools
Becky Jackson Psychology rebecca.jackson@york.ac.uk	Computational Modelling; Semantic cognition; Executive control; fMRI; MEG	Brain Health
Daniel Jeffares Biology daniel.jeffares@york.ac.uk	Population genomics; Genome-wide association studies; Plasmodium; Leishmania	Infection	Molecular Mechanisms and Tools, Immunity
Beth Jefferies Psychology beth.jefferies@york.ac.uk	Semantic; fMRI; MEG; TMS; Memory	Brain Health	Biomedical Healthcare Technologies
Vicki Jennings Biology vicki.jennings@york.ac.uk	Oncolytic Viruses; Cancer; Macrophages; non-coding miRNA; Immunity	Cancer, Infection	Immunity, Biomedical Healthcare Technologies
Steve Johnson School of PET steven.johnson@york.ac.uk	Biosensors; Infection; Electrochemistry; Microfluidics; Co-design	Infection, Cancer	Biomedical Healthcare Technologies, Immunity
Paul Kaye HYMS paul.kaye@york.ac.uk	Leishmaniasis; Immunopathology; Myeloid cells; Vaccines; Immunotherapy	Infection	Immunity
David Kent Biology david.kent@york.ac.uk	Leukaemia; Haematopoietic stem cells; Single cell biology; Physical biology of stem cells; Stem cell niche	Cancer, Infection	Biomedical Healthcare Technologies, Immunity
Ioannis Kourtzelis HYMS ioannis.kourtzelis@york.ac.uk	Macrophage phagocytosis; Inflammation resolution; Anti-tumour immunity; Leukocyte adhesion; Myeloid cell plasticity	Cancer, Infection	Immunity, Biomedical Healthcare Technologies
Thomas Krauss School of PET thomas.krauss@york.ac.uk	Photonic nanostructures; Optical biosensors; Antimicrobial susceptibility; Nanofabrication technology	Infection	Biomedical Healthcare Technologies
Dimitris Lagos HYMS dimitris.lagos@york.ac.uk	Immunity; microRNAs; lncRNAs; RNA-binding proteins; Gene expression regulation	Cancer	Immunity
Alison Layton HYMS alison.layton1@nhs.net	Acne; Scarring; Clinical Trials; Antimicrobial resistance; Psycho-dermatology	Brain Health, Cancer	Immunity, Biomedical Healthcare Technologies
Mark Leake School of PET mark.leake@york.ac.uk	Biophysics; Single-molecule; Bioimaging; Super-resolution; Single-cell	Infection, Cancer, Brain Health	Immunity
Chris MacDonald Biology chris.macdonald@york.ac.uk	Membrane trafficking; Cell surface membrane proteins; Yeast genetics; Fluorescence microscopy; Biochemistry	Infection, Cancer	Molecular Mechanisms and Tools, Immunity
Andrew Mason Biology andrew.mason@york.ac.uk	Stem cell exhaustion	Cancer	Biomedical Healthcare Technologies
Clive McKimmie HYMS clive.mckimmie@york.ac.uk	Immunology; virology; vector biology; vascular biology; dermatology	Infection	Immunity
Sean Meaden Biology sean.meaden@york.ac.uk	Phage; bacteria; metagenomics; evolution; virulence	Infection	Biomedical Healthcare Technologies
Tony Morland Psychology antony.morland@york.ac.uk	fMRI; Visual Neuroscience; psychophysics; evoked potentials and field; transcranial magnetic stimulation (TMS)	Brain Health
Jeremy Mottram Biology jeremy.mottram@york.ac.uk	Neglected Tropical Diseases; Target Validation; Drug Discovery; Trypanosoma; Leishmania	Infection	Molecular Mechanisms and Tools
Purba Mukherjee Chemistry purba.mukherjee@york.ac.uk	Protein-primed replication; biocatalysis; kinetics; protein engineering; nucleic acid bioconjugates		Molecular Mechanisms and Tools
Elmarie Myburgh HYMS elmarie.myburgh@york.ac.uk	Host-pathogen interactions; Leishmania; in vivo imaging; Immunology; Macrophages	Infection	Immunity
MaryAnn Noonan Psychology maryann.noonan@york.ac.uk		Brain Health
Agnes Noy School of PET agnes.noy@york.ac.uk	Molecular modelling; DNA supercoiling; DNA:protein recognition; 3D genomics; Gene therapy	Infection	Biomedical Healthcare Technologies, Molecular Mechanisms and Tools
Peter O'Brien Chemistry peter.obrien@york.ac.uk	Fragment-based drug discovery; SARS-CoV-2; chemical biology; medicinal chemistry; organic synthesis		Molecular Mechanisms and Tools
Alison Parkin Chemistry alison.parkin@york.ac.uk		Infection, Cancer	Molecular Mechanisms and Tools, Biomedical Healthcare Technologies
Samadhan Patil School of PET samadhan.patil@york.ac.uk	Point-of-care diagnostics; Bio-sensors; Metabolomics; Antimicrobial resistance; Bio-mechanics	Infection, Cancer, Brain Health	Biomedical Healthcare Technologies
Kyla Pennington Psychology kyla.pennington@york.ac.uk	Stress; Psychobiology; Mental health; Adverse childhood events; Genetic risk	Brain Health	Biomedical Healthcare Technologies
Damian Perez Mazliah HYMS damian.perezmazliah@york.ac.uk	B cells; Antibodies; Parasites; Chagas disease; Trypanosoma	Infection	Immunity, Biomedical Healthcare Technologies, Molecular Mechanisms and Tools
Alex Pike Psychology alex.pike@york.ac.uk	Mental health; Eating disorders; Anxiety disorders; Computational psychiatry; Neuroimaging	Brain Health
Michael Plevin Biology michael.plevin@york.ac.uk	Protein-RNA interactions; microRNAs; Leishmania; Structural biology; Protein phase separation	Infection	Molecular Mechanisms and Tools, Biomedical Healthcare Technologies
Paul Pryor HYMS paul.pryor@york.ac.uk	Lysosome biogenesis; Autophagy; Ageing; Cell biology; Membrane traffic	Infection	Biomedical Healthcare Technologies
Steven Quinn School of PET steven.quinn@york.ac.uk	Single-molecule spectroscopy; Alzheimer’s disease; Fluorescence; Protein interactions; Model-membranes	Brain Health, Cancer	Molecular Mechanisms and Tools, Biomedical Healthcare Technologies
kim Robinson HYMS kim.robinson@york.ac.uk	innate immunity; skin biology; inflammatory skin disease; inflammasome; 3D skin organotypics	Infection, Cancer	Immunity, Biomedical Healthcare Technologies
Eve Roman Health Sciences eve.roman@york.ac.uk	Haematological malignancies; childhood cancers; epidemiological methods; adverse reproductive events	Cancer
Nathalie Signoret HYMS nathalie.signoret@york.ac.uk	Molecular cell biology; Immunology; Infectious diseases; Virology	Infection, Cancer	Immunity, Molecular Mechanisms and Tools
Alex Smith Health Sciences alexandra.smith@york.ac.uk	Epidemiology; Leukaemia; Lymphoma; Myeloma	Cancer	Immunity, Biomedical Healthcare Technologies
Stephen Smith School of PET stephen.smith@york.ac.uk	AI and Machine Learning; Intelligent medical devices; Neurodegenerative conditions; Cell tracking; Characterisation and classification	Brain Health	Biomedical Healthcare Technologies
Jenny Southgate Biology j.southgate@york.ac.uk	Urothelium; Bladder cancer; Tissue engineering and regenerative medicine; Transcriptomics; Differentiation	Cancer, Infection	Biomedical Healthcare Technologies, Immunity
Chris Spicer Chemistry chris.spicer@york.ac.uk	Biomaterials; Tissue engineering; Protein chemistry; Chemical biology		Molecular Mechanisms and Tools, Biomedical Healthcare Technologies
Sean Sweeney Biology sean.sweeney@york.ac.uk	Drosophila genetics; Neuromuscular junction; Frontotemporal Dementia; Amyotrophic Lateral Sclerosis (ALS); Pathological signalling	Brain Health	Biomedical Healthcare Technologies
Gavin Thomas Biology gavin.thomas@york.ac.uk	Sialic acid; Symbionts of disease vectors; Human microbiome; Escherichia coli; Haemophilus influenzae	Infection	Molecular Mechanisms and Tools, Biomedical Healthcare Technologies
Reidun Twarock Maths reidun.twarock@york.ac.uk	Virus assembly; packaging signals; viral infection models; antiviral therapy; gene vectors	Infection	Molecular Mechanisms and Tools, Biomedical Healthcare Technologies
Katrien Van Bocxlaer HYMS katrien.vanbocxlaer@york.ac.uk	Skin drug delivery; topical formulation development; skin models; cutaneous leishmaniasis	Infection	Immunity
marjan van der woude HYMS marjan.vanderwoude@york.ac.uk	Bacteria; Pathogenesis; Molecular Microbiology; Heterogeneity; Interdisciplinarity	Infection	Immunity, Molecular Mechanisms and Tools
Alex Wade Psychology alex.wade@york.ac.uk	Vision; Attention; fMRI; EEG; Neuroimaging; Neuroscience	Brain Health	Biomedical Healthcare Technologies
Pegine Walrad Biology pegine.walrad@york.ac.uk	Leishmania; Pathogen; Gene regulation; Motility; RNA	Infection	Biomedical Healthcare Technologies, Immunity, Molecular Mechanisms and Tools
Lianne Willems Chemistry lianne.willems@york.ac.uk	Mass spectrometry; Interdisciplinary science; Protein glycosylation; Therapeutics production; Environmental contamination	Infection	Molecular Mechanisms and Tools
Laurence Wilson School of PET laurence.wilson@york.ac.uk	Imaging; Bioinformatics; Parasitology; Biological physics; Motility	Infection	Biomedical Healthcare Technologies
Gavin Wright HYMS gavin.wright@york.ac.uk	Protein interactions; Kinetoplastids; Vaccines; Membrane proteins	Infection	Immunity
Miko Yamada HYMS miko.yamada@york.ac.uk	molecular pathology in skin; clinical trials; transdermal delivery; imaging Biomarker discovery in skin diseases	Cancer	Biomedical Healthcare Technologies