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York Biomedical Research Institute

Drawing researchers together to drive fundamental research in biomedical and clinical science.

Our mission at the York Biomedical Research Institute (YBRI) is to advance discoveries in biomedical science, to inspire, train, and mentor the next generation of biomedical researchers. We aim to understand disease processes to positively impact health and wellbeing.

We host over 100 principal investigators whose expertise covers a range of disciplines, addressing biomedical challenges on regional, national and global scales.

Contact us

York Biomedical Research Institute
+44 (0)1904 328845
B/H/002, Department of Biology, Wentworth Way, University of York, York, YO10 5NG

We aim to unravel the secrets of chronic and infectious diseases using state-of-the-art technology and creative thinking. Our ambition is to carry out research that is relevant nationally and has global reach.

Professor Jeremy Mottram, Director of the York Biomedical Research Institute

Interdisciplinary research themes

Molecular and cellular medicine

Embraces how cells specialise to form and maintain healthy, functional tissues and the mechanisms that fail in chronic degenerative disease.

Immunology, haematology and infection

Covers cellular immunology, host-pathogen interactions, pathogen biology, and experimental and population haematology.


Spans research into molecular mechanisms to behaviour of the whole organism, while also embracing patient-based studies.

Research without boundaries

Our interdisciplinary research is carried out by both individual researchers and scientific teams. Our aims are to integrate techniques, concepts, and theories from multiple disciplines to advance fundamental understanding of biomedical problems. Our cross-theme topics are:

MSc by Research in Biomedical Science

This one-year research course in Biomedical Science provides an opportunity for graduates to complete a masters level course in a specific area of interest.

See programme details

PhD in Biomedical Science

Our PhD in Biomedical Science provides an opportunity for outstanding graduates with an interest in biomedical research.

See programme details

We have facilities for translating scientific discoveries into new treatments and conducting clinical trials.

Impact on human health and wellbeing

Clinical and translational research in YBRI builds on expertise across the University of York, the Hull York Medical School and the York & Scarborough Teaching Hospitals NHS Foundation Trust.

We provide an environment that can deliver early phase clinical trials (Phase I and II) and that supports discovery science in humans and models (in vivo, ex vivo and in silico) with the potential to significantly improve human health.

Current projects include developing a human challenge model for Leishmania (LeishChallenge); and contributing to the dose reduction immunobridging and safety study of two HPV vaccines in Tanzanian girls trial (DoRIS).

Find out about our clinical and translational research