Molecular genetics & development - BIO00052I

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  • Department: Biology
  • Module co-ordinator: Dr. Betsy Pownall
  • Credit value: 20 credits
  • Credit level: I
  • Academic year of delivery: 2018-19
    • See module specification for other years: 2019-20

Module summary

This is an intermediate level module focussing on the genetic and epigenetic regulation of development in multicellular organisms. The module examines how classical genetic, molecular genetic, biochemical and embryological analyses have elucidated the gene regulatory involved in development.

Module will run

Occurrence Teaching cycle
A Autumn Term 2018-19 to Summer Term 2018-19

Module aims

This is an intermediate level module focussing on the genetic and epigenetic regulation of development in multicellular organisms. The module examines how classical genetic, molecular genetic, biochemical and embryological analyses have elucidated the gene regulatory involved in development. The module will also discuss the highly conserved nature of developmental mechanisms and examine how knowledge of key regulatory developmental pathways can inform our understanding of human genetic disorders. Throughout, emphasis is placed upon experimental evidence that underpins our current understanding of gene function and the mechanisms regulating development. Lectures will be suported by textbooks, and where appropriate primary research literature. Practical sessions will support understanding of bioinformatic and experimental approaches that can be employed for the analysis of gene regulation in development. Workshop sessions will encourage and enable students to make use of knowledge gained during the module to solve novel problems regarding gene function in development.

Module learning outcomes

Students who successfully complete this module will have the ability to:

1. Describe the molecular genetic and epigenetic mechanisms regulating development.

2. Describe how knowledge of the conserved mechanisms regulating development has been important for understanding the genetic basis of some human diseases.

3. Interpret experimental evidence related to gene function, epigenetic regulation and genetic disorders.

4. Understand how a toolkit of techniques can be used to investigate gene function, and be able to apply this knowledge to design rationale experimental approaches to answer problems related to development of multicelluar organisms.

5. Understand and explain how the study of gene function in development is relevant to many aspects of modern biology.

6. Appreciate the types of career available to researchers in this area of biology

Assessment

Task Length % of module mark
University - closed examination
Molecular Genetics & Development
2.5 hours 100

Special assessment rules

None

Reassessment

Task Length % of module mark
University - closed examination
Molecular Genetics & Development
2.5 hours 100

Module feedback

Marks will be made available four weeks after the assessment, the paper with specimen answers and generic feedback will be posted on the VLE once marking is complete and scripts will be returned to students at the end of the summer term.

Indicative reading

Key texts are available in the module VLE site.



The information on this page is indicative of the module that is currently on offer. The University is constantly exploring ways to enhance and improve its degree programmes and therefore reserves the right to make variations to the content and method of delivery of modules, and to discontinue modules, if such action is reasonably considered to be necessary by the University. Where appropriate, the University will notify and consult with affected students in advance about any changes that are required in line with the University's policy on the Approval of Modifications to Existing Taught Programmes of Study.