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Physical biochemistry: measurement, analysis & applications - BIO00020C

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  • Department: Biology
  • Credit value: 30 credits
  • Credit level: C
  • Academic year of delivery: 2026-27
    • See module specification for other years: 2025-26

Module summary

“Physical biochemistry” runs through the whole academic year and explores the basis of the experimental toolbox used by biochemists to ask biochemical questions about biological systems. The module contains a consideration of atomic and molecular structure, energy and thermodynamics leading in to the physical basis of spectroscopies relevant to biochemistry. Concepts and practice around using databases of biochemical data and applying separations science will be integrated with an introduction to tools in data analysis and practical experimental design.

Module will run

Occurrence Teaching period
A Semester 1 2026-27 to Semester 2 2026-27

Module aims

“Physical biochemistry” runs through the whole academic year and explores the basis of the experimental toolbox used by biochemists to ask biochemical questions about biological systems. The module contains a consideration of atomic and molecular structure, energy and thermodynamics leading in to the physical basis of spectroscopies relevant to biochemistry. Concepts and practice around using databases of biochemical data and applying separations science will be integrated with an introduction to tools in data analysis and practical experimental design.

Module learning outcomes

To be able to explain how light interacts with matter in ways that can be used experimentally by biochemists, to gain understanding of biological systems

To build and use experimental equipment in a laboratory setting to collect and analyse data about biological systems

To use sequence and structure databases to make predictions about macromolecular structure and function

To apply data analysis techniques to experimental data

To explain and use standard methods for separation of biological materials

To design simple experiments using biological and spectroscopic methods

 

Module content

The module will include teaching in these areas:

Atomic structure, energy, thermodynamics

Physical basis of spectroscopy

Build a spec

Databases, intro to seq. analysis

Proteins and separations

Data analysis inc. statistics

Protein Absorption

Protein purification and interactions

Experimental design: microscopy versus optical density

Indicative assessment

Task % of module mark
Closed/in-person Exam (Centrally scheduled) 70.0
Essay/coursework 30.0

Special assessment rules

None

Indicative reassessment

Task % of module mark
Closed/in-person Exam (Centrally scheduled) 70.0
Essay/coursework 30.0

Module feedback

Through supported learning in workshops. Through specimen questions and answer on the VLE. Through return of marked scripts after the assessment.

Indicative reading

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The information on this page is indicative of the module that is currently on offer. The University constantly explores ways to enhance and improve its degree programmes and therefore reserves the right to make variations to the content and method of delivery of modules, and to discontinue modules, if such action is reasonably considered to be necessary. In some instances it may be appropriate for the University to notify and consult with affected students about module changes in accordance with the University's policy on the Approval of Modifications to Existing Taught Programmes of Study.