Infection

Infectious diseases caused by viruses, parasites, and bacteria present significant global challenges to human health and economic stability. At the York Biomedical Research Institute (YBRI), researchers ask fundamental questions spanning from whole ecosystems to atomic structures to tackle these major global health threats.

Our work in virology focuses on fundamental mechanisms of viral assembly, replication, and host cell interaction, driving the development of novel vaccines and antiviral therapies. In experimental parasitology, YBRI leads research into devastating diseases such as malaria, leishmaniasis, and trypanosomiasis, advancing new drug discovery, vaccine development, and insights into host immune regulation.

Our bacterial infection research explores fundamental mechanisms of bacterial DNA replication, antimicrobial resistance (AMR), and the complex interplay between bacteriophages and bacterial populations, paving the way for innovative antibacterial interventions.

By combining molecular insights with clinical and epidemiological expertise, YBRI investigators advance public health, combat drug-resistant pathogens, and develop effective therapies to protect global communities against infectious threats.

a man observes his monitors in a laboratory

Research snapshots

Pioneering Subunit Vaccine Candidates Against Animal African Trypanosomiasis

Theme leads

YBRI members

For a full list of YBRI members, including researchers’ interests and relevance to our disease pillar and cross cutting themes, visit our members’ page.

See the list of YBRI members