Cancer

We bring together scientists, clinicians, epidemiologists, and external partners across disciplines to advance the understanding of cancer across scales, from single molecules to whole populations. We aim to translate our discoveries to new therapeutic strategies that are both effective and precise.

We focus on three key areas:

Blood cancers (Centre for Blood Research): We study mechanisms driving blood cancer development, haematopoietic stem cell biology, and the interaction of leukaemic cells with their niche.
Solid cancers (Jack Birch Cancer Research Unit): We explore the microenvironment of solid cancers, including breast, bladder, colorectal, ovarian, and kidney cancer.
Cancer immunology (Centre for Blood Research and Jack Birch Cancer Research Unit): We investigate the interactions between cancer and immune cells to increase tumour immunogenicity and reduce adverse effects of cancer immunotherapies.

A microscope lens focuses closely onto cells held on a piece of glass

Research snapshots

Theme leads

YBRI members

For a full list of YBRI members, including researchers’ interests and relevance to our disease pillar and cross cutting themes, visit our members’ page.

See the list of YBRI members

Cross-cutting themes

Immunity

Researching fundamental immune mechanisms across diseases to develop advanced diagnostics and promote healthy ageing.

Molecular mechanisms and tools

Combining interdisciplinary approaches to understand molecular processes in disease.

Biomedical healthcare technologies

Uniting cross-specialty researchers to create innovative medical devices and cutting-edge treatments.

Infection

Explore infection

Brain health

Explore brain health