- Department: Physics
- Module co-ordinator: Dr. Mikhail Bashkanov
- Credit value: 10 credits
- Credit level: H
- Academic year of delivery: 2022-23
- See module specification for other years: 2021-22
Having taken Nuclear Physics as part of Quantum Physics II in stage 2 is advantageous; Independent study material will be available (15 pages from University Physics)
Occurrence | Teaching period |
---|---|
A | Autumn Term 2022-23 |
The course will give an overview of the physics, methods and equipment employed in modern medical physics. The basic interaction processes of particles with matter are outlined, including the interaction of ionising and non-ionising radiation with biological systems. Radiotherapy methods including brachytherapy, molecular therapy, external beam therapy (neutron, photon, proton, ion, anti-proton) and the effects of radiation at the cellular level are presented. The course will outline latest development in intensity-modulated mixed-beam radiotherapy. Methods to measure and monitor radiation are discussed. Methods and signal processing employed for high-field/squid MR imaging, PET imaging, SPECT imaging, and ultrasound will be presented. Methods of production (reactor based, cyclotron based, isotope generators) and use of various radiopharmaceuticals will be discussed. Practical use of various detection techniques and methods will be demonstrated in a laboratory sessions. The course will include a significant component based on computer simulation. Links to industry will also be explored.
At the completion of the course students will have acquired the skills to:
Students will work individually and in groups in both workshop and laboratory environments, with input and support from postgrads and RAs.
Lecture 1: Introduction. Course structure.
Lecture 2: Tomography, basic principles and mathematical methods. The overview of modern tomography techniques. Imaging.
Lecture 3: The basic interaction processes of particles with matter. Interaction of ionising and non-ionising radiation with biological systems.
Lecture 4: Detectors. Scintillating detectors (plastic, crystals), Solid state, Trackers, Compton cameras.
Lecture 5: Positron Emission Tomography (PET). Basic principles. Detectors. Imaging software. Single Photon Emission Computed Tomography (SPECT). Computed tomography (CT).
Lecture 6: Applied PET
Lecture 7: Radiotherapy. Brachytherapy, molecular therapy, external beam therapy (neutron, photon). Intensity modulated radiotherapy. Effects of radiation at cellular level.
Lecture 8: External hadron beam therapy (proton, ion, anti-proton). Accelerators for hadron beam therapy. Beam properties. Mixed beam therapy.
Lecture 9: Project meeting. GEANT4 computer simulation software.
Project 1: Simulation of radiation interaction with matter. GEANT4. Detector design.
Project 2: Simulation of external beam therapy with GEANT4.
Lecture 10: Nuclear radio-isotopes used in medicine. Methods of production (nuclear reactors, cyclotrons, isotope generators). Radiopharmaceuticals.
Lecture 11: Magnetic Resonance Imaging (MRI/MRT). Physics of MRI. Signal processing. High-field MRI. Squid-MRI. MRI equipment.
Lecture 12: Applied MRI.
Lecture 13: Exotic tomography (muon, ultrasound, electric resistivity, seismic)
Lecture 14: Modern development in medical physics. Cutting-edge technologies, detectors, techniques. The medical physics of tomorrow.
Lecture 15: Radiation safety and security. Radiation protection standards. Dosimetry. Radiation sources. Radiation protection in case of nuclear accidents.
Lecture 16: Visit to the MRI/PET or medical facility.
Lecture 17: Dosimetry and natural radioactivity.
Seminar: Students' presentations of their project results.
Lecture 18: Questions.
Tutorials: 6 Sheets, 5 question each.
Task | Length | % of module mark |
---|---|---|
Essay/coursework Medical Physics Assignment |
N/A | 40 |
Essay/coursework Medical Physics Project |
N/A | 60 |
None
Projects
Project 1: Simulation of external beam therapy with GEANT4. (reference example – standard tissue and 10MeV photon beam.)
Task | Length | % of module mark |
---|---|---|
Essay/coursework Medical Physics Assignment |
N/A | 40 |
Essay/coursework Medical Physics Project |
N/A | 60 |
Our policy on how you receive feedback for formative and summative purposes is contained in our Department Handbook.
The course book is
Applications of Modern Physics in Medicine, Mark Strikman, Kevork Spartalian & Milton W. Cole
Other books students might find useful:
General Nuclear Medicine
Nuclear Cardiology:
PET/CT:
Physics:
Board Review: