- Department: Chemistry
- Module co-ordinator: Prof. Paul Walton
- Credit value: 10 credits
- Credit level: M
- Academic year of delivery: 2022-23
- See module specification for other years: 2021-22
Occurrence | Teaching period |
---|---|
A | Spring Term 2022-23 to Summer Term 2022-23 |
This module explores the way in which biology is increasingly inspiring the design of new chemical systems and materials. Apart from the inherent fascination of discovering how biological systems work, we can also learn about the circumstances under which things can go wrong, and—in the longer term—hope to improve on nature. This module provides an overview of how chemists attempt to model the high efficiency of nature’s catalysts (enzymes) – in particular focussing on ‘difficult’ reactions. The course also indicates how biology can be used as a source of inspiration in materials science, and how using biology as inspiration may also lead to ‘greener’ chemical products based on renewable, biologically compatible resources.
Bioinorganic Model Complexes I, 6 lectures, PHW
Principles of inorganic models; reasons for models. Models of haemoglobin and myoglobin. Other O2-transport proteins: haemocyanin, haemerthyrin. Copper oxidases for cellulose degradation.
Bioinorganic Model Complexes II, 6 lectures, AKDK
Bioinorganic Organometallic Chemistry. Artificial metalloenzymes.
Molybdenum and Iron enzymes, 6 lectures, AP
Examples of mononuclear Mo/W enzymes, incl nitrate reductase, aldehyde oxidase, xanthine oxidase. Hydrogenases (how biology handles hydrogen). Models of nitrogenase.
Enzyme Kinetics of Metalloenzymes, 1 x 2h unassessed workshop, AP
Task | Length | % of module mark |
---|---|---|
Closed/in-person Exam (Centrally scheduled) Assessed workshop : Bioinorganic model complexes |
2 hours | 30 |
Online Exam -less than 24hrs (Centrally scheduled) Online exam : BI exam online exam |
4.25 hours | 70 |
None
Comprehension questions on scientific paper (unseen in advance of the workshop). Topic of assessment, material from the PHW course.
Online examination (based on 1.5-hour paper delivered over 4.25 hours online). Answer two compulsory 20-mark questions. Topics of exam questions, material from AKDK and AP courses.
Task | Length | % of module mark |
---|---|---|
Closed/in-person Exam (Centrally scheduled) Assessed workshop : Bioinorganic model complexes |
2 hours | 30 |
Online Exam -less than 24hrs (Centrally scheduled) Online exam : BI exam online exam |
4.25 hours | 70 |
Written and/or oral feedback for workshops will be given either during the sessions or within a week.
Exam results with per-question breakdown are returned to the students via supervisors within 5 weeks (as per special approval by the University Teaching Committee). Outline answers are made available via the Chemistry web pages when the students receive their marks, so that they can assess their own detailed progress/achievement. The examiners’ reports for each question are made available to the students via the Chemistry web pages.
This is a research-led course so up-to-date scientific publications will form the majority of the reading