We focus on the development of new methods for the synthesis of molecules with applications in organic, inorganic, and biological chemistry. 

Distinctively, our work is underpinned by fundamental, mechanism-led research that seeks to combine experimental, spectroscopic and computational approaches. Our wide-ranging, innovative activities include:

  • Fundamental studies in transition metal catalysis
  • Mechanistic physical organic chemistry
  • Prebiotic/origins of life chemistry
  • Target molecule synthesis
  • Macrocycles
  • Data-driven reaction optimisation
  • Main group organometallic chemistry

Our applied research projects address global challenges such as antibiotic resistance, environmental remediation and environmental sustainability. We have strong links with the pharmaceutical and agrochemical industries. 


Duncan Bruce
  • Materials chemistry
Victor Chechik
  • EPR and nanoscale chemistry
Paul Clarke
  • Total synthesis of natural products
  • Prebiotic chemistry
  • Origins of life
Caroline Dessent
  • Physical chemistry of gas-phase biological ions
  • Gas-phase inorganic chemistry
  • Mass spectrometry
Richard Douthwaite
  • Molecular and materials chemistry
  • Photocatalysis
Simon Duckett
  • Organometallic chemistry
  • Reaction mechanisms
Anne Duhme-Klair
  • Metal ions in biology and medicine
Ian Fairlamb
  • Transition metals in synthesis, catalysis and chemical biology: reactivity, mechanism and applications
Martin Fascione
  • Chemical glycobiology
  • Synthetic carbohydrate chemistry
  • Chemical/enzymatic modification of proteins
Pratibha Gai
  • Surface science
  • Catalysis
  • Nanomaterials
  • Atomic processes
  • Electron microscopy developments
Gideon Grogan
  • Structure, function and application of novel biocatalysts
Roderick Hubbard
  • Structure-based drug discovery
Michael James
  • Charge-Transfer Complexes in Organic Synthesis
Peter Karadakov
  • Modern valence-bond theory and chemical reactivity
  • Ab initio calculation of NMR properties
Jason Lynam
  • Transition metal and main group chemistry

Duncan Macquarrie
  • Heterogeneous catalysis

  • Green chemistry: development and applications of novel organic-inorganic hybrid materials
Avtar Matharu
  • Green and sustainable chemistry: biobased chemicals, processes and materials

Michael North
  • Green organic chemistry

Peter O'Brien
  • Development of new methods in synthesis and medicinal chemistry

Alison Parkin
  • Electrochemical insights into redox-active metalloproteins, bacterial metabolism and catalysis

Robin Perutz
  • Organometallic photochemistry
  • Small molecule activation
  • Catalysis and solar fuels

Anne Routledge

  • Bio-organic chemistry

John Slattery

  • Ionic liquids
  • Computational chemistry
  • Main-group chemistry

David Smith

  • Dendrimer, supramolecular and nanoscale chemistry

Richard Taylor

  • The total synthesis of compounds of biological importance: design and development of new synthetic methods
William Unsworth
  • Synthetic chemistry, macrocycles, spirocycles, natural products

Paul Walton
  • Bioinorganic chemistry

Andrew Weller
  • Organometallic Chemistry: Synthesis, Catalysis and Mechanism
Luke Wilkinson
  • Paddlewheel-porphyrin conjugates for solar harvesting applications