Funded projects
Biomedical science
- Translation of Leish@York Research
- A new non-antibody scaffold for in situ detection of pathogens in wastewater
- Taking sleep research out of the laboratory
- Applying parasite genomics to understand cutaneous leishmaniasis
- The influence of inflammation activity and the role of the cerebellum in functional neurological syndromes (Conversion Disorder)
- Effects of 670nm photobiomodulation on mitochondrial function in the human brain
- Characterisation of sodium transport as a novel biomarker of aggression in colon cancer specimens
- Deep sequencing of the C9orf72 GGGGCC-repeat expansion in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)
- Resurrecting ancestral sugars: a novel molecular archaeology approach to Prostate cancer immunotherapy
- Establishing a pipeline for the isolation and expansion of estrogen receptor positive (ER+) cells from healthy volunteers followed by their first characterisation using single-cell transcriptomics
- Establishing single cell RNA-sequencing and ATAC-sequencing to decipher biological heterogeneity in blood cells
- A microfluidic device for in vitro characterision of biomolecular liquid-liquid phase separation: from soft matter physics to biomedical research via solution biophysics
- Matching self-healing hydrogels to diverse cardiac tissues
- Characterisation of a molecular switch between amyotrophic lateral sclerosis and frontotemporal dementia
- Accelerating the development of new alpha therapies for cancer treatment
- Understanding how unwanted memories persist: The role of sleep spindles in emotional memory consolidation
- Infant neural and physiological responses to fear expressions as risk markers for the development of conduct disorders
- Novel methodologies and apparatus for tissue sensitive prompt gamma-ray imaging in proton therapy
- Real Time Magnetic Resonance Imaging of Swallowing and Speech in Patients Following Major Maxillofacial Surgery and Reconstruction
- Developing chaperone therapy for lysosomal storage disease treatment – Treating Mucopolysaccharidosis IIIB with imino-sugars
- Towards non coding RNA-based therapies: Developing innovative mass spectrometry methods to probe function of non-coding RNA immune regulators
- A new partnership to assess zebrafish models of human disease using evolutionary algorithms
- Investigating the relationship between sodium transport inhibitor use and clinical outcomes in cancer patients
- Characterising the role of a novel intellectual disability gene, TLK2, in neuronal development
- Understanding DNA-processing molecular motors from Human Papillomavirus for designing anti-viral drugs
- Microelectronic integrated circuit biosensors for susceptibility testing
- A new approach to stroke aphasia rehabilitation
- Investigating in a cell-free test tube how malfunction in cellular organization causes congenital glycosylation disorders
- Is human type 1 diabetes a result of immunological attack of the thymic quality control machinery?
- A feasibility study to discover if the community of microbes in our guts is affected by the way we receive antibiotics
- Building a strategic partnership between the University of York and the Barts Cancer Institute at Queen Mary University London
- microRNA markers in autism spectrum disorders
- Interpreting the electrical signals in the nervous system - towards a framework for therapeutic benefit
- Investigating the causes of changes in hearing ability using brain stimulation
- Building a Partnership for Cognitive Neuroscience between the University of York and Maastricht University
- Development of a humanised mouse model of schistosomiasis
- Artificial enzymes for selective antibiotic activation
- Chemical re-engineering of lipoteichoic acid (LTA) to decrypt its dynamic interplay with host cell surfaces
- The role of long non-coding RNA in infectious, inflammatory, and vascular diseases
- Measuring functional magnetic resonance signals in rodents
- Probing the role of ion channels in microglial activation using in vivo models
- Validation of preclinical models of ZAK-linked myopathy
- Pharmaceutical Optimisation using a Laboratory Automated Reaction Intelligent System (POLARIS)
Humanities and social sciences
- How do personal experiences of autism affect views of genetic research into autism?
- Does the gender achievement gap in education point toward a mental health gap? Potential pathways to narrowing gender disparities in education
- Mental Health of Children with Special Educational Needs and Disabilities during the Coronavirus Pandemic
- Tackling early childhood undernutrition and obesity in Jamaica, 1962-2018
- The origins of healthcare in its social context
- Health inequalities and the use of cannabis and cannabidiol for pain relief: a study in two deprived areas
- Workshop to develop research proposals related to sustainable wellbeing and the UN Sustainable Development Goals
- Architectures for a post-antibiotic age: the co-design of an exhibition
- Engaging with the Deaf Community: Raising awareness of the British Sign Language Translation of the Strengths and Difficulties Questionnaire
- SINGSVR: Simulating Inclusive Natural Group Singing in VR
- Digital games to tackle common mental health problems in children and young people
Population health
- How do personal experiences of autism affect views of genetic research into autism?
- Does the gender achievement gap in education point toward a mental health gap? Potential pathways to narrowing gender disparities in education
- Understanding what influences orthopedic surgical decision making: a mixed methods systematic review
- Sleep in a time of COVID-19
- Engagement workshops about inequalities in, and under-identification of, common mental disorders in the perinatal period
- Exploring the potential for Integrated Medicine approaches to improve the health and wellbeing of HIV/AIDS patients in rural Tanzania
- How can community reporters assist an understanding of experiences of food insecurity over the summer holiday amongst low-income families?
- The Closing the Gap cohort: building a platform for York-led interdisciplinary research programme in mental health
- The Umbrella Consortium – bringing together the global leaders in research into infection in children with cancer
- A feasibility study into producing a national housing profile of people with severe mental illness
- Developing methodologies to determine the fate of antibiotics and their metabolites in food crops in order to inform risk assessment for human health
- International collaboration to support English and Dutch patients with Medically Unexplained Symptoms(MUS), their carers and clinicians to independently formulate research priorities for their condition
- Implementing the Person-Centred Community Care Inventory (PERCCI) as a measure for quality in older people’s mental health and social care services
- Health inequalities and the use of cannabis and cannabidiol for pain relief: a study in two deprived areas
- Infant neural and physiological responses to fear expressions as risk markers for the development of conduct disorders
- Tobacco smoking among people living with HIV in Uganda: understanding the problem to inform effective interventions
- Polypharmacy in children and young people with life-limiting conditions: understanding the problem and identifying research priorities
- Mental Health First Aid: An intervention for improving mental health?
- A mixed methods evaluation of the impact of extending working hours in a large Mental Health Trust: assessing employee and organisational outcomes
- Developing a training intervention for staff to improve participant recruitment into randomised controlled trials
- University of York Student Wellbeing Cohort
- Addressing mental & physical health comorbidity in Low and Middle Income Countries in South Asia: establishing the York Mental and Physical Comorbidity Global Health Research Group
- Cochrane Global Mental Health: Mapping existing mental health evidence and knowledge mobilisation for people in Low and Middle Income Countries (LMICs)
- Demonstrating the Viability of Analytics for Unsupervised Healthcare Data Collection
Product development and applied research
- Improving cleft palate treatment with acoustics: Detecting Velo-Pharyngeal Insufficiency using external noise excitation
- Optimised, scaled-up production of exosomes from mesenchymal stem cells through outsourced process development
- Personalising Mental Health Treatments for Young People Using Machine Intelligence (ProMetheUs)
- A Novel Platform Technology for Synthetic Vaccines and Gene Delivery Systems
- Case studies of local NHS equity indicator trends: Have some NHS areas tackled health inequality more effectively than others, and if so how?
- Development of a Patient and Public Involvement in Research Network (PIRN) at the University of York (PIRN@York)
- Architectures for a post-antibiotic age: the co-design of an exhibition
- Implementing Outcome Feedback technology in NHS IAPT Mental Health Services
- Engaging with the Deaf Community: Raising awareness of the British Sign Language Translation of the Strengths and Difficulties Questionnaire
- TB & Tobacco PLUS: A plan to integrate and scale up tobacco cessation within TB programmes in Bangladesh and Pakistan
- SINGSVR: Simulating Inclusive Natural Group Singing in VR
- Repurposing of an approved drug for Frontotemporal Dementia
- Targeting epigenetic reader proteins to develop new drugs for Leishmaniasis
- Drug Delivery for Treatment of Neurodegenerative Diseases using Gels (NEURO-GELS)
- Digital games to tackle common mental health problems in children and young people
- Development of an automated device to monitor circadian changes in vision
- Pharmaceutical Optimisation using a Laboratory Automated Reaction Intelligent System (POLARIS)
- Specialist Paediatric Palliative Care Input for Children with Malignancies
- A Novel Framework for Enriching and Expediting Statistical and Uncertainty Analyses of Complex Computer Models of Biological Systems