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York Structural Biology Laboratory

An award-winning laboratory with a global reputation.

York’s biological chemistry research, including structural and chemical biology has its epicentre in the York Structural Biology Laboratory (YSBL).

Our work focuses on the fundamental chemical bases for biological and biochemical processes, the use of small molecules to probe cellular biology, software and methods development and on the exploitation of enzymes in biocatalysis. In 2019 we were awarded the Queen’s Anniversary Prize for our pioneering work in protein molecule research.

Read about the history of YSBL

Contact us
+44 (0)1904 328259
York Structural Biology Laboratory, University of York, Heslington, York YO10 5DD.

YSBL has a long and successful tradition of collaborative research with academic and industrial partners. This has included the hosting of numerous visitors from around the world, providing hands-on training and experience of practical and computational aspects of protein structure determination and analysis.

Professor Anthony Wilkinson, Head of York Structural Biology Laboratory


Established in 1976 by Professors Guy and Eleanor Dodson


Winners of the 2019 Queen's Anniversary Prize


70 staff and PhD students, including 13 academic staff and research fellows

Research and innovation focus areas

The laboratory's research can be categorised broadly under three main headings:

Our industry partnerships

The laboratory engages in research collaboration and forms partnerships that enhance the quality of its research and lead to impact in industry and in medicine.

We develop widely used and highly cited computational methods used by structural biologists, both academic and industrial, worldwide.

Software written by YSBL colleagues has contributed to the discovery and development of frontline drugs. There are close links with Novozymes in research that has led to improved enzymes used in washing powders, the paper and pulp industry as well as in food manufacturing and biofuel production.

Case Studies


Work with us

We have cutting-edge facilities and we'd like to hear from prospective reseachers and industry partners.

Contact us
+44 (0)1904 328259
York Structural Biology Laboratory, University of York, Heslington, York YO10 5DD.