The Structural Biology Group investigates the structures of proteins and their complexes with other proteins, nucleic acids and ligands.
Increasing use of high throughput technologies means that many hundreds of different proteins are under study at any one time, with the targets selected on the basis of their biochemical or biological function. In addition, there is great expertise in York in protein chemistry and crystallisation for tackling challenging proteins, such as multi-molecular complexes or membrane proteins.
When integrated with exploration of the cell and molecular biology of the targets, the group's structural work is providing major insights into the molecular mechanisms underlying biological function.
