Mark Simmonds
Research Fellow
Email: mark.simmonds@york.ac.uk
Tel: 01904 321091
Fax: 01904 321041
Mark is a medical statistician with a particular interest in statistical methodology for meta-analysis. His research interests include the meta-analysis of individual patient data, time-to-event data and of medical screening tests. He is also interested in preventive medicine and medical screening for cardiovascular and other diseases.
Mark has a PhD in medical statistics from the University of Cambridge, where he developed statistical methods for individual patient data meta-analysis. Since then he has been engaged in trial design and meta-analysis of pharmaceutical trials and has engaged in statistical research in preventive medicine, including meta-analyses in the prevention of dementia, and investigating the cost-effectiveness of methods of screening for future cardiovascular disease.Selected publications
Simmonds MC, Tierney J, Bowden J, Higgins JPT. Meta-analysis of time-to-event data: a comparison of two-stage methods. Research Synthesis Methods 2011; 2:139-49
Bowden J, Tierney J, Simmonds M, Copas AJ, Higgins JPT. Individual patient data meta-analysis of time-to-event outcomes: one-stage versus two-stage approaches to estimating the hazard ratio under a random effects model. Research Synthesis Methods 2011 ;2:150-62
Wald NJ, Simmonds M, Morris JK. Screening for future cardiovascular disease using age alone compared with multiple risk factors and age. Plos One 2011;6:e18742
Simmonds M. Genetic profiling tests in screening for cardiovascular disease. J Med Screen 2011;18:56-57
Wald DS, Kasturiratne A, Simmonds M. Serum homocysteine and dementia: meta-analysis of eight cohort studies including 8669 participants. Alzheimers Dement 2011;7:412-7
Wald DS, Kasturiratne A, Simmonds M. Effect of folic acid, with or without other B vitamins, on cognitive decline: meta-analysis of randomized trials. Am J Med 2010;123:522-527