Carbon-carbon bond forming enzymes from plants

Context

Carbon-carbon bond formation is an essential reaction in organic chemistry and a defining step in the specialised metabolic pathways that yield high-value natural products. Enzymes and pathways in nature that control these reactions demonstrate high levels of stereoselectivity and regioselectivity. Such biocatalysts, or biocatalytic cascades, are ideal candidates to be integrated into industrial biotransformation and synthetic biology platforms.

The research 

Our research bridges the gap between plant biosynthesis and industrial application. We  express, engineer and deploy C-C bond forming enzymes from plants to establish bio-based routes for the synthesis of valuable chemical intermediates.