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Completed Projects

Randomised controlled trials

AESOPS: the effectiveness and cost-effectiveness of opportunistic screening and stepped care interventions for older harzardous alcohol users in primary care

This research study is looking at the effectiveness and cost-effectiveness of opportunistic screening and stepped care interventions for older hazardous alcohol users in primary care.

Funded by: NIHR HTA‌

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ACT AD: Assertive Community Treatment in alcohol dependence

ACTAD is a randomised control trial to determine the effectiveness of ACT for the treatment of alcohol dependence compared with standard treatment.

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Evaluation of the Alcohol Improvement Programme

This project aims to evaluate the effectiveness, cost-effectiveness and appropriateness of the Alcohol Improvement Programme, the effectiveness of the Early Implementation Programme, and the effectiveness and appropriateness of each programme component, and its contribution to the AIP as a whole.

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Interactions between problem substance users and hospital staff

This study aims to investigate the experiences and attitudes of problem substance users and hospital staff in a single acute care setting in the UK. 

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NIQUAD : Nationally Integrated Quantitative Understanding of Addiction Harms

NIQUAD aims to shed new light on the scale of substance use and substance-specific harms, and examine the natural history, intervention effects and impact in reducing or magnifying such harms.

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UK Centre for Tobacco Control Studies

UKCTCS is a strategic partnership of nine UK universities in England and Scotland (Nottingham, Bath, Birmingham, Edinburgh, Stirling, Queen Mary, UCL, York and Bristol) involving leading tobacco control researchers from a range of disciplines.

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CITADEL: A feasibility study and pilot trial of computerised cognitive behaviour therapy for depression in adolescents

The Lime Trees Research team were recently awareded a grant from the Research for Patient Benefit (RfPB) to investigate the effectiveness of computerised Cognitive Behaviour Therapy (cCBT) for adolescents with depression.

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Is there a link between folate, folate metabolism and depression?

We propose to use Mendelian randomisation and genetic epidemiology to more fully understand dietary associations and modifiable environmental risk factors in psychiatric disease.

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NIHR Senior Investigator Award

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Archived Projects

A dynamic model of adult smoking related costs and consequences for England

Alcohol Measures for Public Health Research Alliance (AMPHORA)

Image of the EU flag.
To be used with projects with EU funding.

AMPHORA aims to create a European Alcohol Policy Research Alliance of internationally renowned alcohol policy researchers which will undertake new empirical research to strengthen the overall European research base of the impact of public health measures and interventions, including taxes, pricing, availability, access, advertisement, drinking environments, and early diagnosis and treatment of disease in multiple settings, geographical regions, gender and age groups to guide integrated policy making to reduce the harm done by alcohol.

Funded by: The European Commission

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Estimating the costs of smoking in pregnancy

ODHIN: Optimizing delivery of health care interventions

SIPS: screening and brief interventions

A review of methods to identify postnatal depression in primary care

A trial platform of enhanced care for depression in primary care

CADET: Multi-Centre randomised controlled trial of collaborative care for depression

Developing evidence based and acceptable stepped care systems in mental health: an operational research study

SNAP - Smoking, Nicotine and Pregnancy

The SNAP trial investigates whether Nicotine Replacement Therapy (NRT) helps pregnant women to give up smoking, whether it is cost-effective and if it has any effect on the subsequent behaviour and development of their children over the next two years.

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COBID: A feasibility trial of behavioural activation to improve depression for people with substance misuse

The aim of this study is to find out whether psychological therapies are effective for people with substance misuse. This study will investigate how many people with substance use problems and depression are willing to engage with brief psychological therapy, how many complete this, and what participants think about this psychological treatment. We also want to find out if participants who benefit from treatment have certain things in common; for example their use of alcohol or drugs or their level of dependence on substances.

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CLAHRC: Improving Prevention of Vascular Disease in Primary Care

This programme will develop and test means of identifying people at risk from vascular disease in primary care and undertake the foundation-laying research required for large scale randomised clinical trials of evidence-based preventative approaches to tackle psychological barriers to health change.

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CLAHRC: Translating Research into Practice in Leeds and Bradford (TRiP-LaB)

TRiP-LaB will work with four other CLAHRC research themes and their associated clinical and service user communities to develop, implement and evaluate strategies for evidence-based change in services.

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Early parenting interventions for families with young children showing severe attachment problems: an integrated evidence synthesis

Attachment, the relationship between caregiver and child, is a crucial factor in an infant's ability to develop healthy relationships. Research has identified different types of attachment relationships.

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Translation of the Strengths and Difficulties Questionnaire into British Sign Language

We are doing some research to check that we have correctly translated a questionnaire for young people into British Sign Language (BSL). The questionnaire is used to ask people about emotional and other difficulties.

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Smoking cessation for people with severe mental illness: a pilot study and definitive randomised evaluation of a bespoke service (SCIMITAR)

This study will develop a 'bespoke smoking cessation' service targeted to meet the needs of those with serious mental health problems such as schizophrenia, and will test the clinical and cost effectiveness of this approach in a randomised controlled trial.

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MCLASS: Muslim Communities Learning About Second-Hand Smoke

Muslim Communities Learning About Second-hand Smoke (MCLASS) is a cluster, randomised, controlled pilot trial of 'Smoke Free Homes' delivered in Islamic religious settings (mosques hosting communal prayers, study circles for women and Qur'an classes for children) with embedded preliminary health economic and qualitative analyses.

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