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Bob is a Professor of Paediatrics and Evidence Synthesis at the Centre for Reviews and Disseminiation at the University of York and Hull/York Medical School, and an Honorary Consultant in Paediatric / Teenage-Young Adult Oncology at Leeds Children's Hospital.
He is also the Director of Candlelighters Supportive Care Research Centre, where his main areas of work are in the development of supportive care for children with cancer, individual participant data (IDP) meta-analysis, and the development of skills in appraisal and translation of clinical research in practice. He is the lead of the PICNICC collaboration, "Predicting Infectious ComplicatioNs In Children with Cancer" which was formed by engaging clinical and methodological experts from 22 different study groups from 15 countries, parent representatives and healthcare researchers to investigate patterns of risk in febrile neutropenia.
Bob has worked extensively to promote and teach evidence-based practice with the Centre for Evidence-based Medicine in Oxford, UK, and also the Centre for Evidence-based Child Health (Institute of Child Health, London, UK). He edits the evidence-based practice sections of the Archives of Diseases in Childhood, and is an associate editor of the journal. He has lectured in the UK, Europe, North America, Australia and the Nordic Countries on the subject of evidence-based practice, and has written widely on this.
Bob was the Clinical Lead for the NICE Guideline (CG151) on the management of neutropenic sepsis. In addition to the work in febrile neutropenia, he has undertaken many systematic reviews assessing the quality of evidence underlying interventions to ameliorate the side-effects of cancer treatments in childhood and is actively involved with developing and implementing high-quality clinical practice guidelines with the iPOG group. This includes systematic reviews of the treatment of chemotherapy-induced nausea and vomiting, constipation, nutritional support, nephropathy and mucositis.