Economic Evaluation seminar: Economic evaluation of Antimicrobial Resistance interventions
This event has now finished.
Event details
Antimicrobial resistance (AMR) is a growing global health challenge, and standard approaches to economic evaluation may fail to capture its full connectivity and complexity. In particular, many analyses do not consider indirect or long-term effects, which may limit their relevance for informing policy. This talk will present work carried out as part of a PhD that explores ways of framing and extending economic evaluations in the context of AMR. A review of the economic evaluation literature indicates that existing studies tend to adopt short time horizons and narrow geographical scopes and overlooks wider cross-pathogen and cross-sectoral effects. To provide a basis for considering these wider impacts, a conceptual framework—the AMR development map—was developed, drawing on biological and ecological principles to propose the key dimensions of AMR burden, including time, physical space, One Health sectors, and the wider pathogen pool. The temporal dimension is then examined in greater depth, using inter-disciplinary literature to outline and consider different types of time horizons, the distribution of intervention effects over time, and sources of temporal uncertainty, with the aim of linking conceptual considerations to applied modelling. These ideas are explored in a case study of a hospital-based screening intervention for carbapenemase-producing Enterobacteriaceae, where a transmission and cost-effectiveness model is extended to incorporate longer time horizons and sources of temporal uncertainty, such as spatial transmission dynamics and pathogen evolution. The analysis suggests that broadening the scope of evaluation can influence intervention cost-effectiveness, highlighting that wider-scope analyses may be important when guiding policy decisions.
If you are not a member of University of York staff and are interested in attending a seminar, please contact alfredo.palacios
