The Molecular Interactions laboratory houses a range of equipment for the analysis of the biophysical properties of molecules as well as protein-protein and protein-nucleic acid interactions. Techniques available include UV-visible, fluorescence and circular dichroism spectrophotometry, surface plasmon resonance (SPR), isothermal titration calorimetry (ITC) and microscale thermophoresis (MST) for study of interactions and analytical ultracentrifugation (AUC) and light scattering (SEC-MALLS) for molecular size and shape, and a nanoDSF instrument for protein stability studies. We also have mass spectrometry equipment for whole protein MW, multipurpose plate reader systems for 96- and 384-well plate assays and gel and plate imager systems for fluorescence gel scanning and autoradiography work. We can advise on techniques and train you on most of our equipment, or run experiments as a service depending on your requirements. Our facilities are available to internal and external users and both academic and commercial organisations are welcome to enquire.
Technology Facility, Department of Biology
University of York, Wentworth Way, York, YO10 5DD, UK
Tel: 01904 328723
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