UK Biological Imaging Facilities

This site is no longer updated.

Please add your facility information to the new Database on the Royal Microscopical Society site.

Thank you





Kevin Mackenzie
+44 (0)1224 437447

Miep Helfrich
+44 (0)1224 437443

Microscopy and Histology core Facility
University of Aberdeen
Institute of Medical Sciences
AB25 2ZD


  • Internal on all instruments
  • External commercial & academic on application
  • DIY or Full service work

Core Facility; Histology, Electron Microscopy, MicroCT




Confocal microscopy
Zeiss 700 Laser Scanning Confocal Microscope
Zeiss 710 Laser Scanning Confocal Microscope
Fluorescence microscopy
Zeiss Imager M2 + Apotome
Zeiss Observer Z1
Zeiss PALM Laser Microdissection system
Slide Scanner
Zeiss Axioscan Z1
Micro CT
SkyScan-1072 High-resolution desk-top micro-CT system
Live cell Imaging
Delta Vision Core wide field imaging system with EMCCD
Perkin Elmer Ultraview Spinning Disk
Tissue processors, standard and motorized microtomes for wax and resin sectioning
Cryostat for frozen sectioning
Leica Bond-max fully automated immuno-stainer
Electron Microscopy
JEOL 1400 plus TEM and XR16M-ActiveVu camera
Zeiss EVO MA10 SEM with Oxford Inca microanalysis
Leica UC6, UC7 R2 ultramicrotomes
Cryo Electron Microscopy
Leica Empact 2 High Pressure Freezer (with rapid transfer system)
Leica AFS (Automated Freeze Substitution) processor
Leica FC6 cryo-ultramicrotome

Bath, Microscopy & Analysis Suite (MAS)

Ursula Potter (Technical Manager and all enquiries)
+44(0)1225 385651

Adrian Rogers (Confocal & Flow)
+44(0)1225 386681

John Mitchels (EM & scanning probe microscopy)
+44(0)1225 385153

Microscopy & Analysis Suite (MAS)
Building 3 West 2.11-2.16
University of Bath


  • Primarily for University of Bath researchers and post-graduate students
  • External academic and commercial available on request

SEM and TEM (materials and biology related), CLSM, AFM, Raman, FACs, high content microscopy, EDX & FTIR.

Confocal Microscopy
Zeiss LSM510 META, 4 lasers including 405nm diode and environmental chamber
Zeiss LSM510 META, 3 lasers
High Content Microscope
GE Healthcare IN Cell Analyser 2000
Plate reader
MSD SECTOR Imager 6000
Calcium Imaging
Concord Calcium Imager
Electron Microscopy
JEOL 630IF FESEM (with Cryo and EDS)
JEOL 6480LV SEM (with EDS) 
Elemental Analysis
High sensitivity Oxford Instruments INCA X-Act SDD X-ray detector for EDX analysis
Optical Spectroscopy
Perkin Elmer Frontier Fourier Transform Infrared Spectroscopy (FTIR)
Renishaw inVia Raman spectroscopy system
Scanning Probe Microscopy
Veeco multimode Nanoscope III (AFM, STM, MFM, LFM etc)
Flow Cytometry
Becton Dickinson FACSCAnto
Becton Dickinson FACS Aria III cell sorter
Specimen Preparation
Critical point dryer
Freeze dryer
Freeze slammer
Ion beam mill
Sputter coater
Dimple grinder
Grinding wheel
Data Analysis
Oxford Instruments INCA Energy 350
Veeco Nanoscope analysis software



Ken Mills 
+44 (0)2890972786

Bioimaging Core Technology Unit
School of Medicine Dentistry and Biomedical Sciences
Queens University of Belfast
Medical Biology Centre
97 Lisburn Road
Northern Ireland


  • Internal on all instruments
  • External commercial & academic on application
  • DIY or full support service
  • Proof of principle/ developmental studies undertaken
Core Facility, dedicated staff for each imaging platform. Computational methods for quantitative image analysis. Content Management Systems for all images, central server with remote access.
Workshops, training courses, teaching. Embedded Cat 2 facilities with microbiological safety cabinets and animal holding suite.

Confocal Microscopy
Leica TCS SP5 with DMI6000+Solent live cell chamber (Cat 2 facility)
Fluorescence Microscopy
Zeiss Axiovert 200 with Axiovision
Leica DMI6000B with FW4000
Live Cell Imaging
Zeiss Axiovert 200 with Eppendorf Injectman +Femtojet (Cat 2 facility)
Virtual Microscopy
Aperio CS Scanner
Aperio OS Scanner
Hamamatsu Nanozoomer
in vivo Imaging
Xenogen IVIS 200
BD FACSAria II (Cat 2 facility)

Birmingham, BALM

 Alicia Hidalgo
(co-director of BALM)
+44 (0)121 414 5416

Alessandro Di Maio
(Experimental Officer of BALM)
+44 (0)121 414 5416

Birmingham Advanced Light Microscopy Facility (BALM)
School of Biosciences
University of Birmingham
B15 2TT


  • Internal, mostly used by School of Biosciences
  • External academic: used by many other Schools within this University
  • External commercial subject to access charges
  • Can be used as DIY or with technical help

Core facility, confocal microscopy on fixed and live samples (time-lapse and cell culture).
Computational methods for quantitative image analysis, object recognition, cell tracking and probes development.

Future requirements
Computational methods for imaging

Confocal microscopy
Leica SP2 AOBS upright and inverted (4 lasers)
Zeiss LSM 710 ConfoCor
Confocal/TIRF microscopy
Nikon A1R confocal/TIRF with spectral detector, EM-CCD, and Piezo-Z drive
Widefield/TIRF microscopy
Olympus IX81 widefiled/TIRF system with ORCA R2 and ImageEM CCD camera
Fluorescence imaging
Nikon Eclipse TE600 fluorescence microscope with digital Hamamatsu CCD camera.
Zeiss Axioskop 50 fluorescence microscope with digital image capture.


Dr Jonathan Salvage (Academic Lead)
+44 (0)1273 642430

Mr Andrew Flint (Senior Technician- FT)
+44 (0)1273 642430

Mr Michael Helias (Senior Technician -PT) 
+44 (0)1273 642430

Image and Analysis Unit (IAU)
School of Pharmacy and Biomolecular Sciences
University of Brighton
Huxley Building
Lewes Road
BN2 4GJ 


  • Internal academic research and teaching
  • External academic collaborations
  • External commercial consultancy

Core facility; SEM, ESEM, STEM, EDS, Cryo-SEM, AFM, CLSM.
Image and analysis commercial consultancy 

Confocal microscopy
Leica TCS SP5 confocal laser scanning microscope (CLSM) with a DM1600 inverted microscope and live cell imaging chamber.
Fluorescence imaging 
Nikon Eclipse TE2000-U fluorescence microscope with digital SLR camera.
Zeiss Axioskop 50 fluorescence microscope with digital image capture.
Electron microscopy 
Zeiss SIGMA FEG-SEM with SE, In-lens, BSE and STEM detectors, Quorum PP3000T Cryo-SEM and Oxford Aztec EDS elemental analysis with X-Max detector.
Zeiss EVO LS-15 environmental chamber SEM with SE, VPSE and BSE detectors, extended variable pressure chamber, water vapour injection, Deben cold stage and Oxford Aztec EDS elemental analysis with X-Max detector.
Quorum Q150T turbo molecular pumped sputter coating system.
Both systems equipped with large (42") screen TV monitors for seminars, training, or teaching events.
Atomic Force microscopy
Digital Instruments Multimode Nanoscope Probe III AFM.
Digital Instruments Dimension 3000AFM.
Light microscopy
Motic stereo microscope bright field/dark field microscope with digital image capture and Alicona TEX reconstruction and analysis software.
Nikon Eclipse ME600 bright field/dark field microscope fitted digital image capture and Alicona TEX reconstruction and analysis software.
Data Physics OCA optical contact angle analysis system.
Malvern Zetasizer Nano particle size system.
Access and use of a comprehensive range of analytical facilities within the school, including HPLC, GC, LC-MS, UV-Vis, fluorescence, FT-IR, NIR, Raman, AAS, NMR, X-ray, DSC.
Access and use of cell and tissue culture facilities within the school.
Access and use of microbiology facilities within the school.

Bristol, Wolfson Bioimaging Facility

Mark Jepson (light microscopy)
+44 (0)117 33 12143

Paul Verkade (electron microscopy)
+44 (0)117 33 12179

Wolfson Bioimaging Facility
Faculty of Medical and Veterinary Sciences
University of Bristol
University Walk


  • Currently most use is Bristol-based and subject to access charges
  • Scope for external collaborations in speciality areas.

Integration of light and electron microscope facilities. Live cell imaging (especially intracellular trafficking, model organisms, bacterial infection). Correlative light and electron microscopy (CLEM).

Future requirements
Tools for image analysis, especially tracking.

Confocal microscopy
Confocal laser scanning microscopes (5 inverted Leica CLSM systems: SP8 AOBS tandem scanner, 3 SP5 AOBS, SP2 AOBS).
Multiphoton microscope (Upright Leica SP8 with CLSM).
Spinning disk confocal (Perkin Elmer UltraVIEW ERS 6FE).
Wide-field microscopy
Wide field microscopes (4 WFM systems: Leica AF6000 system, 3 other Leica microscopes with CCD cameras (Hamamatsu, Photometrics, Leica).
TIRF (Leica AM TIRF MC system for total internal reflection fluorescence microscopy or wide-field imaging).
Electron microscopy
TEM (FEI Tecnai 12: 120kV transmission electron microscope).
STEM (FEI Tecnai 20: 200 kV twin lens scanning transmission electron microscope; suitable for cryo-EM and electron tomography).
SEM (FEI Quanta 400 variable pressure scanning electron microscope). 
Extensive EM preparation facilities .
Offline image analysis suite.


Richard Adams
+44 (0)1223 333782

Department of Physiology, Development and Neuroscience
University of Cambridge
Downing Street

Time-lapse imaging, image processing, computational methods

Image analysis.
Cell tracking and cell shape analysis in whole embryos.
Computational analysis of tissue dynamics during embryogenesis.


Matt Wayland
+44 (0)1223 769282

Imaging Facility
Department of Zoology
University of Cambridge
Downing Street


  • Internal (80% on all instruments)
  • External commercial & external academic (20% on all)
  • DIY or full service work

Core Facility
Image analysis and programming

Confocal microscopy
Leica SP5 invert
Leica SP5 upright
Leica SP upright
UltraView CSU-10 Spinning Disk
MicroPoint laser ablation / microdissection
Live cell imaging chamber on SP5 invert (up to 37oC and 5% CO2


Alexandre Kabla
+44 (0)1223 766208

Department of Engineering
University of Cambridge
Trumpington Street

Imaging, computational methods

Image Analysis
Image processing and mechanical properties of multicellular assemblies


Clemens Kaminski
+44 (0)1223 763135

Laser Analytics Group
Department of Chemical Engineering and Biotechnology
University of Cambridge
Pembroke Street


  • Internal
  • External
  • DIY

All aspects of quantitative multidimensional microscopy

Confocal microscopy
Custom built widefield FLIM platform with LED and Supercontinuum excitation (430-700 nm). Both ultrahigh speed FLIM (15 fps at full field) and excitation at multiple modulation frequencies are possible.
Custom designed hyperspectral imaging confocal station, with supercontinuum excitation (430-700 nm excitation / emission, at electronically selectable, arbitrary wavelength combinations). Full resolution of fluoresence excitation and emission spectrum, fluorescence lifetime and polarisation state. TCSPC, Fluorescence Anisotropy Imaging
Leica SP5 confocal platform with resonant scanner.


David Klenerman
+44 (0)1223 336481

The University Chemical Laboratory

Dept of Chemistry
University of Cambridge
Lensfield Road

Laser fluorescence spectroscopy and scanning probe microscopy

Fluorescence microscopy
Two colour total internal reflection single molecule fluorescence microscope


Jeremy Skepper
+44 (0)1223 333774

Janet Powell
+44 (0)1223 333774

Cambridge Advanced Imaging Centre (CAIC)
Anatomy Building
Physiology Development and Neuroscience,
University of Cambridge
Downing Site


  • Internal
  • External
  • Commercial.
  • DIY and service work.

Specimen preparation, ambient and low temperature, stereology, x-ray microanalysis, immunocytochemistry, bio-materials microscopy, physiological and time-lapse microscopy.

Confocal microscopy and LMD
Leica SP1- multiphoton (invert)
Leica SP1-UV (invert)
Leica SP2-405 - 633 (invert)
Leica SP2-456 - 633 (invert)
Leica SP5-456 - 633 (invert physiology)
Leica LMD 6000 (upright laser microdissection microscope)
LaVision Trimscope multiphoton system
Electron microscopy
FEI Verios 460 XHR FEGSEM with Quorum Cryo and EDAX EDX
FEI Technai G2 200 kv, STEM, tomgraphy, cryo-transfer, HAADF, SAED, CBED, EDAX Genesis EDX, Deben AMT digital camera
FEI-Philips XL30 FEGSEM, SE and BSE detectors
Oxford INCA EDX with 30mm pentafet ATW detector
Quorum Emitech PP2000 cryotransfer system
Specimen preparation
Leica VT1000S vibrating blade microtome
Leica CM 3050S Cryostat
Leica CPC plunge and impact freezing device
2 x Leica AFS freeze substitution and low temperature embedding devices
3 x Leica Ultracut E
Leica Ultracut UCT
Leica Ultracut S and FCS cryosectioning device
Edwards 306 auto, Carbon coater, freeze drier and glow discharge unit
Quorum Emitech K575X dual head Au and Cr sputter coater and remote pumping station for TEM cryo-transfer specimen holder
Polaron CPD

Cambridge, Babraham

Simon Walker
+44(0)1223 496618

Imaging Facility
The Babraham Institute
CB22 3AT


  • Full access to external users, though internal users get priority.
  • DIY or Full service work

Core Facility
Live cell fluorescence imaging

Confocal microscopy
Zeiss LSM 780 invert
Olympus FV1000 invert 
Nikon A1R MP
Andor Revolution Spinning Disk with 2x EM CCD (Andor)
Nikon A1R MP
Zeiss LSM-7MP (with OPO)
Super Resolution

Fluorescence imaging
Olympus Xcellence (CellR)
Nikon live cell imaging station (with 2x sCMOS)
Andor TIRF system (with 2xEM CCD)
High Content Screening
InCell Analyser 6000
BD Pathway 855
MetaSystems Metafer / MetaCyte
Laser Micro-dissection
Zeiss MicroBeam

Cambridge, Gurdon Inst.

Alex Sossick 
+44 (0)1223 334082

Wellcome Trust/Cancer Research UK Gurdon Institute 
University of Cambridge
Tennis Court Road


  • Priority given to Gurdon Institute users
  • Limited outside access

Core Facility. Immunofluorescence; widefield epifluorescence and confocal microscopy, deconvolution

Confocal microscopy
Confocal scanning laser microscopes and multi-photon system
Widefield deconvolution and high throughput systems

Cambridge, WT-MRC Stem Cell Institute

Peter Humphreys (light microscopy)
+44(0)1223 760200

Andy Riddell (flow cytometry)
+44(0)1223 760227

Centre For Stem Cell Research
Tennis court Road

Core Facility, Specimen Prep - Histology Facility, timelapse imaging, image analysis

Leica SP5 invert + live cell chamber
Leica SP5 invert
Andor Revolution XD spinning disk
Zeiss LSM710
Leica Matrix HCS widefield
GE Incell Analyser
Nikon Biostation IM
Essen Incucyte Zoom
Zeiss AxioExaminer
Zeiss AxioImager Apotome
Leica DMI4000
Olympus IX51 plate scanner

Flow Cytometry
Biorad S3


Jim Ralphs
+44 (0)2920 874954

Tony Hayes
+44 (0)2920 876611

Marc Isaacs
+44 (0)2920 876611

Confocal Microscopy Unit
Cardiff School of Biosciences
Cardiff University
CF10 3AX


  • Internal (mainly), but also external commercial & academic

Core Facility; Immunofluorescence; Widefield epifluorescence and confocal microscopy

Confocal microscopy
Leica TCS SP2 AOBS laser scanning confocal microscope. Twin microscope configuration comprising upright (DM6000) and inverted (DMIRE2) stands (laser lines: 405, 458, 476, 488, 514, 543 & 633nm), galvonometer & electromotor stages; Solent Scientific incubation chamber with CO2/humidity and temperature regulators for in vitro work; brightfield, fluorescence, DIC and polarizing optics
Fluorescence imaging
Olympus BX series microscopes with fluorescence, DIC and brightfield optics refer to web pages for further information


Charlotte James
+44 (0)2920 687004

Central Biotechnology Services
Henry Wellcome Building
School Of Medicine
Cardiff University
Heath Park
CF14 4XN


  • Internal and external users
  • Academica and Industry
  • User access or managed service

Core facility, academic consultancy, certified to ISO 9001 and ISO 17025

Confocal microscopy
3 x Leica SP5

Flow cytometry
1 x Beckman Cyan ADP 9 colour
2 x BD FACS Canto II 8 colour
1 x BD  FACS Calibur 3 colour
1 x BD FACS Aria III cell sorter (11 colours 3 laser instrument)


Jan Hobot 
+44 (0) 2920 742131

Chris von Ruhland 
+44 (0) 2920 742132

Electron Microscopy Facilities
Central Biotechnology Services 
Institute for Translation, Innovation, Methodology and Engagement (TIME)
School of Medicine 
Cardiff University 
Heath Park 
CF14 4XN


  • Internal and external both academic and commercial.

Core facility. 
Specimen preparation at ambient or low temperature for structural or immunocytochemical studies. 
First-hand knowledge of modern acrylics (Lowicryls and LR White). 
Tokuyasu or cryosubstitution methodologies. 
Histology and LM preparations. 
TEM and SEM X-ray microanalysis. 
X-ray microanalysis of asbestos and mineral fibres in post mortem tissue.

Fluorescence imaging 
Olympus BX51 Upright with Zeiss AxioCam camera.
Olympus CK40 Inverted with Polaroid digital camera.
Reichert Polarising Microscope.
Electron microscopy 
Philips CM12 TEM with SIS MegaView III camera and EDAX
Genesis X-ray microananalysis system.

JEOL 840A SEM with ADDA SIS digital imaging and INCA x-sight detector X-ray microanalysis system with elemental mapping plus Oxford CT1500 Cryosystem and stage. 
Specimen Preparation 
Leica EMTP Tissue Processor. 
Reichert KF80 metal mirror/plunge freezer. 
Dedicated Histology room.


Chris Marshall 
+44 (0) 2920 748164

Wales Research and Diagnostic PET Imaging Centre
School of Medicine 
Cardiff University 
University Hospital of Wales
Heath Park 
CF14 4XN


  • Internal (80% on all instruments)
  • External commercial & external academic (20% on all)
  • DIY or Full service work

Neuroimaging, Radiochemistry, PET 

Clinical PET 
GE 690 TOP PET CT Scanner
Pre Clincal Scanner
FLEX Triumph Multi Modality Pre Clinical Platform
Synthera and TRASIS AIO


Jason Swedlow
+44 (0)1382 385819

Swedlow lab
Wellcome Trust Centre for Gene Regulation & Expression
College of Life Sciences
University of Dundee
Dow Street

Open Microscopy Environment

Structured illumination microscopy on OMX, expertise on high content screening and live cell imaging, development of data management tools and specifications for microscopy.

Future requirements
Money for meetings and travel to other sites for access and sharing of info and smart, programmable microscopes.



Sam Swift
+44 (0)138 238 6412

Central Microscopy Facility
College of Life Sciences
MSI/WTB Complex
University of Dundee
Dow Street


  • User training/DIY for light microscopy
  • DIY or Full Service for EM
  • External academic / industry welcome by appointment

Core facility; High resolution imaging, live cell imaging, FLIM, FRET, FRAP, immuno EM etc

Light Microscopy
Zeiss LSM 710 confocal/multiphoton
Zeiss LSM 510 META
Leica SP2
Zeiss Laser dissection
Becker and Hickl TCSPC FLIM
DeltaVision Elite restoration microscopes with EMCCD, Live Cell Chambers and ring-TIRF
Nikon TIRF
OMX Structured Illumination Microscope
Electron Microscopy
FEI Tecnai 12 TEM
Jeol 1200 EX TEM
Hitachi s4700 FESEM


Markus Posch (Scientific Officer for OMX)
+44 (0)138 238 6414

OMX Super-Resolution Microscopy
College of Life Sciences
University of Dundee
Dow Street


  • Open to the scientific community
  • Euro BioImaging Proof of Concept site(Advanced Light Microscopy - General Access)

Structured Illumination (3D-SIM) Super-Resolution
Superfast Live Imaging (multichannel stacks)

OMX Blaze (Applied Precision - GE)
 4 channel SIM
 1 fps SIM (live)
 100 fps 4 channel (simultaneous)        widefield image stacks


Tim Hawkins (Advance Light Microscopy)
+44 (0)191 334 1333

Christine Richardson (Electron Microscopy)
+44 (0)191 334 1285

Microscopy and Bioimaging Facility
School of Biological & Biomedical Sciences
Durham University


  • Internal on all instruments
  • External commercial & external academic
  • DIY or Full Service


Core facility; High resolution imaging, FRET, FRAP, FLIP, FLIM, sFLIM, FCCS, FLCS, Super resolution, 3D-SIM, PALM, dSTORM, deconvolution. 5D live cell imaging, TIRF, photoactivation/conversion,
ImmunoGold, Cryosectioning, Ultramicrotomy, Sterology.
Licenced to image plant:pathogen interactions within facility.
Collaboration & developments of new techniques (eg photonics, chemical probes)


Future requirements
SuperResolution, FCCS & FLIM
Confocal microscopy
Leica TCS SP5 Tandem head AOBS Invert (Resonant scanner) with FLIM and FCCS (APD & Spectral detectors)
Zeiss LSM 510 META invert
BioRad Microradiance Upright
Andor Revolution XD Spinning Disk Invert
Super Resolution
GE OMX BLAZE V.4 (3D-SIM) + DLM (Monet) localisation microscopy (PALM/sSTORM). This is a 6 laser 4 sCMOS system with environmental control.
Fluorescence Imaging
Leica MC TIRF Microscope
Zeiss Apotome Microscope
Zeiss Live Cell Imaging System
EM CCD Imaging
Most of the above microscopes are within live cell imaging/environmental chambers
Upright (DM2500) and inverted (DMI3000) DIC microscopes + multiple injection systems to work with a wide variety of organisms and tissues. HD imaging system.
Electron Microscopy
Hitachi H7600 TEM
High resolution Hitachi S5200 FESEM + Cryostage
Image analysis
Suite of high-end 64-bit PC workstations
Sample Preparation
Leica High Pressure Freezer EMPACT
Leica AFS freeze substitution and low temperature
Leica Ultracut S room temperature
Leica FC6 cryo-ultramicrotome
Leica Knife maker
Baltec Critical Point Drier
Cressington coating units (Carbon, platinum, chromium, tungsten)
Leica CPC cryo workstation
Leica IGL. Automatic immunogold labeller
Leica MM80E metal mirror/plunge freezer
Tissue processing
Cryostat for frozen sectioning
Microtomes for wax and resin sectioning
Leica vibrating diamond knife


Edinburgh IGMM Advanced Imaging Facility

Ann Wheeler
+44 (0)131 467 8425

Matthew Pearson

Harris Morrison

Alan Serrels

Martin Lee

Neil Carragher - Discovery Unit

Advanced Imaging Facilit
Institute of Genetics and Molecular Medicine
University of Edinburgh
Crewe Road South


  • Flat fee for internal users
  • External to IGMM
  • Super-resolution £40 per hour

Core facility.
Development of new imaging methodologies, F-techniques, Live cell imaging, High content screening, Super-resolution imaging

Super-resolution microscopy (ESRIC)
Confocal Microscopy
Nikon A1R
Leica SP5
Nikon A1
Nikon C1
Fluorescent Imaging
2x inverted live cell imaging systems
EMCCD camera
1x Zeiss/Volocity deconvolution system
4x Zeiss epifluorescent microscopes
Mesoscopic Imaging
OPT (developed in house)
2x Nikon Macroscopes
3x Leica dissecting micrscopes
SPIM in development
In Vivo Imaging Confocal Microscopes
Olympus FV1000 with SIM Scanner
Olympus OV110
Olympus BX51 with DP71 colour camera
High-content Imaging
Olympus ScanR / CellR
ImageExpress Micro (Molecular Devices) (part of the Discovery Unit)
Incucyte Zoom (part of the Discovery Unit)
Two-photon / CARS Microscope
Olympus FV1000MPE with APE picoEMERALD laser system.
The CARS microscope has the following imaging modes available:
Two-photon fluorescence
Fluorescence lifetime imaging (2-channel)
Second harmonic generation
Coherent anti-stokes raman scattering
Stimulated raman scattering
Image Analysis Software
Imaris (complete package)
Autoquant X3 deconvolution
Metamorph premier offline
ScanR High-content analysis offline

Edinburgh BioImaging Facility

Anthony Corcoran (Facility Manager)

Andy Downes (Facility Director)
+44 (0)131 650 5660

Alistair Elfick (PI)
+44 (0)131 650 7254

Edinburgh BioImaging Facility
Institute for BioEngineering
Edinburgh University
Faraday Building


  • Flat fee for internal/external academic use
  • Flat fee for commercial use
  • In conjunction with grant application

Core Facility, development of new imaging methodologies, non-linear optics, in/ex vivo live cell imaging and biological imaging, Ramen spectroscopy, atomic force microscopy

Raman Spectrometer
Invia Renishaw - Leica Inverted Microscope
Multi Photon Microscope
i. Coherent anti-Stokes Raman scattering (CARS)
ii. Stimulated Raman scattering (SRS)
iii. Second harmonic generation (SHG)
iv. Two Photon Excitation Fluorescence (TPEF)
v. Fluorescenc lifetime imaging
Atomic Force Microscope (AFM)
Two systems, Bruker AFM Bioscope which is integrated with the CARS microscope and a standalone AFM Explorer

Edinburgh Brain Research Imaging Centre (BRIC)

Joanna Wardlaw (Director of Centre)
+44 (0)131 537 2943 (PA)

Duncan Martin (Scientific Business Manager)
+44 (0)131 537 2664

Brain Research Imaging Centre 
University of Edinburgh
Division of Clinical Neurosciences
Bramwell Dott Building
Western General Hospital


  • Access through an application process
  • Research and commercial scanning work can be undertaken
Stroke, FMRI, Diffusion and tractography, Perfusion imaging, Aging, Spectroscopy, Psychiatric disorders, Neurodegenerative disorders
1.5T (GE) MRI imaging capabilities
Diffusion and Tractography
Functional MRI
(Simultaneous EEG)
Perfusion and Bloodflow
Temperature Mapping
Radiological advice on imaging and study protocols
Radiological interpretation of scans
Image Analysis methods
MRI Quality Assurance methods
Software tools for image analysis and image management

Edinburgh, CIR, QMRI

Rolly Wiegand (LM)
+44 (0)131 650 2864
CALM - Confocal and Advanced Light Microscopy Facility

Shonna Johnston (Flow)
+44 (0)131 242 6567

Flow Cytometry Facility

Centre for Inflammation Research
Queen's Medical Research Institute
47 Little France Crescent
EH16 4TJ



  • Internal for University
  • External
  • DIY or fully assisted image acquisition


  • Internal
  • External academic on application
  • Sorting service available

Core Facility; Teaching - Microscopy course (twice a year), high resolution cellular microscopy, image restoration and quantitation, live cell imaging

Future requirements
Hardware for deep penetration in/ex vivo live cell imaging and TIRFM

Confocal microscopy
Zeiss LSM 510 META, inverted
Leica SP5, inverted, both eqipped with environmental control
Fluorescence imaging
Olympus Cell P, inverted
Environmental control for live cell imaging
Optical Projection Tomography (Bioptonics 3001)
Image analysis
High-end workstations with SVI Huygens Essential, ImageJ and PE Volocity

Flow cytometry
Cytometry analysers
6L SORP BD Fortessa
5L SORP BD Fortessa
BD Canto
BD Calibur
BD Accuri C6
Cell sorters
BD ARIA Fusion

Edinburgh, Clinical Research Imaging Centre (CRIC)

Edwin J. R. van Beek
+44 (0)131 242 7760
SYNAPSE Chair of Clinical Radiology

Stuart Docherty
+44 (0)131 242 7767

Clinical Research Imaging Centre

University of Edinburgh
Queen's Medical Research Institute
47 Little France Crescent
EH16 4TJ


  • Access through applications process
  • PET-CT 70% NHS service
  • MDCT 50% NHS service
  • MRI 100% research

Core facility.
Imaging-based assessment of structure, function and treatment efficacy

3T MRI (Siemens Verio) with fMRI, multinuclear spectroscopy and MR Elastography
Mock MRI system
320 MDCT (Toshiba Aquilion ONE)
128 mCT-PET (Siemens)
PET-trace 8 cyclotron (GE)
4 GMP hot cells and 3 research hot cells

Image analysis laboratory

Edinburgh, IMPACT

Anisha  Kubasik-Thayil 
+44 (0)131 6503278

IMPACT Imaging Facility 
Hugh Robson Building
George Square


  • Internal for University
  • External
  • DIY or fully assisted image acquisition

Core Facility.
High resolution cellular microscopy, image restoration and quantitation, live cell imaging, TRIF and FLIM

Future requirements 
MP system for in/ex vivo live cell imaging

Confocal microscopy 
Nikon A1R confocal system on a Ti:E inverted microscope. Conventional Galvano and faster resonant scanning options with standard and spectral detectors. Equiped with Becker and Hickl unit for FLIM.
2 Zeiss LSM 510 one inverted and one upright both coupled to a Coherent Mira mode-locked Ti:Sapphire multi-photon laser equipped with environmental control.
Fluorescence imaging 
Olympus Cell R Dual TIRF System, with environmental control for live cell imaging.
Leica inverted and upright systems for epi-fluoresecence imaging.
Image analysis
High-end workstations with SVI Huygens Essential and Pro, ImageJ, Imaris and PE Volocity

Edinburgh, MRC

Mike Millar 
+44 (0)131 242 9155

Histology and Imaging Facility 
MRC, Human Reproductive Sciences Unit
The Queens Medical Research Institute
47 Little France Cres
EH16 4TJ


  • Internal on all instruments
  • External academic on application
  • DIY or Full service work

Core facility.
Confocal microscopy, Stereology and immunohistology with emphasis on multi same species colocalisations.
Reproductive morphology

 Confocal microscopy 
Zeiss 510 Laser Scanning Confocal Microscope
Zeiss 510 META Laser Scanning Confocal Microscope
Zeiss 710 Laser Scanning Confocal Microscope
Widefield microscopy 
Assorted upright and invert research grade microscopes with CCD imaging both in colour and monochrome
Live cell Imaging 
Stereology using Media Cybernetics Image Pro Plus with stereologer plug in
Image Analysis 
Huygens deconvolution software
Volocity 3D imaging software
Media Cybernetics Image Pro Plus
Tissue processors, standard and motorized microtomes for wax and resin sectioning
Cryostat for frozen sectioning
Leica Bond- fully automated immuno-stainer
Intavis whole mount in-situ hybridisation and immunostaining robot

Edinburgh, Orthopaedic Engineering Collaboration

Robert Wallace
+44 (0)131 242 6295

Orthopaedic Engineering Collaboration
Chancellor's Building
University of Edinburgh
Room FU 413
49 Little France Crescent
EH16 4SB


  • Internal (75%)
  • External and commercial (25%)
  • Full service work
  • Induction training and supported DIY

Scan and production of 3D images from samples.
Comprehensive tensile, 3 & 4 point bend tests.
Torsional testing, ultimate strength, fatigue and step loading. Combination of axial and torsional tests.


Xray Imaging
Skyscan 1172
Mechanical Testing
Zwick/Roel z0005


Edinburgh, Roslin Institute

Bob Fleming 
+44 (0)131 6519409

Bio-Imaging Facility
The Roslin INstitute and R(D)SVS
Easter Bush Veterinary Campus
University of Edinburgh
EH25 9RG


  • Internal on all instruments
  • External commercial and academic on application

University Vet School Research Core Facility, Laser scanning confocal, Intravital 2-P, Live cell, Cell sorting and Cytometry

Confocal microscopy 
Zeiss LSM710 invert, live cell insert/tiling/Z-stack/FRAP
Zeiss LSM Pascal upright
Zeiss LSM7MP Intravital 2-P - Coherent Chameleon II with OPO
Live Cell Systems
Zeiss Live Cell Observer deconvolution system
Nikon Eclipse Ti Cell/Organ culture system, Photometrics Coolsnap
Zeiss StereoLumar V12 4-colour fluorescence/Ibidi culture system
Zeiss Axiozoom with environmental chamber (for embryology)
Intravital micro-endoscope
Several Leica/Nikon/Zeiss uprights and inverts with Lumencor SpectraX/Sola LEDs/Hamamatsu cameras
Imaging Software
Zen Desk/Zen Pro (3 copies)
Imaris Bitplane (all modules) on 64 bit imaging PC
FACS Aria III high speed Cell Sorter, 4 laser/13 colour
Cytometry (Contact
BD LSR Fortessa 4 laser/13 colour
Dako Cyan 3 laser
2x BD FACS Caliburs

Edinburgh, Super-Resolution Imaging Consortium (ESRIC)

Alison Dun  
+44 (0)131 4514669

The Edinburgh Super-Resolution Imaging Consortium (ESRIC)
Heriot-Watt University
EH14 4AS


  • Open Access
  • Charge per use
  • DIY or full service

Core facility; super-resolution imaging.
Biophysics: optical development, TCSPC, detector development, novel super-resolution imaging analytical approaches, signal processing. 

Confocal Microscopy
Leica SP5 single molecule detection system, fluorescence lifetime imaging, fluorescence correlation spectroscopy.
Olympus 4-line TIRF (405nm, 491nm, 561nm, 643nm).
Single Molecule Imaging
Photoactivation localisation microscopy (PALM), STORM, GSDIM.
Super-resolution Imaging
Gated (g)STED, Structured illumination microscopy.
Deconvolution microscopy
Laser tweezing/photoporation facility.
Atomic Force Microscopy
Zeiss LSM5 AFM system



Philippe Laissue
+44 (0)1206 872246

Bioimaging Facility
Department of Biological Sciences
Wivenhoe Park
University of Essex


  • Internal on all instruments
  • External commercial & academic on application; Nikon reference site
  • Proof of principle studies undertaken

Core facility, rapid and long term live cell imaging, immunofluorescence, colocalisation, visualisation. Development of specialised instruments and computational methods for quantitative image analysis.

Future requirements
Further in-house development of instruments and algorithms. Super-resolution and FLIM.

Confocal microscopy
Nikon A1R (inverted) with 6 laser lines, hybrid scanner, spectral detector, automated XY and piezo Z,
TIRF/OAF/widefield with EM-CCD, live cell chamber
Bio-Rad Radiance 2000 with Olympus IX70 (inverted)
Widefield fluorescence Microscopy
Nikon Ti-E (inverted) with LEDs and Intensilight, EM-CCD, automated XY and piezo Z, live cell chamber
In-house developed TIRF and OAF instrument (inverted) with EM-CCD and triple split (Kad group)
Various upright and inverted fluorescence and brightfield microscopes with EM-CCD and colour CCD cameras
Several commercial and in-house developed imaging systems for measurement of photosynthesis by gas exchange and fluorescence, both in the laboratory and in the field (Lawson group).
Image Analysis
High end 64-bit workstations for offline image processing and analysis. NIS-Elements, deconvolution. Custom software using ImageJ and Matlab. Workshops, training courses, teaching. Extensive website for booking, training, resources.
Fully equiped Cat 2 laboratory, cell culture facilities

Flow Cytometry
BD FACS Calibur

Glasgow, Beatson

Kurt Anderson
+44 (0)141 330 2864

Beatson Institute for Cancer Research
Garscube Estate
Switchback Road
G61 1BD


  • Priority given to Beatson users, followed by Glasgow University
  • Outside access primarily on a collaborative basis

Live cell imaging, including time and frequency domain FLIM, TIRF, photo-activation / -bleaching / -conversion.
Mouse in vivo imaging, including collagen SHG and use of photo-activation and -bleaching, FLIM and FRET.

Future requirements
Image analysis, super-resolution

Confocal microscopy
Olympus FV1000 (x2)
Nikon A1R
Zeiss LSM 710
Andor Spinning Disk
2x LaVision Bio-Tec TRIM scope
Lambert Instruments custom Spinning Disk
Lambert Instruments custom TIRF
Live Cell
Custom TIRF
Olympus / Volocity Deconvolution system
Medium Throughput Long Term Time Lapse (x4)
Olympus OV100
Ivis Spectrum
Leica AF6000 micro-dissection
Upright stands for histology and immunofluorescence (x4)
Off-line image analysis (x8)



Sally Boxall
+44 (0)113 3437270

Leeds Bioimaging and Flow Cytometry Facility
School of Molecular and Cellular Biology
Faculty of Biological Sciences
University of Leeds


  • Internal and external, academic research groups and commercial

Core Facility.
Collaboration and development of techniques, image processing and analysis. Live cell imaging.

Confocal microscopy
Zeiss LSM 700 inverted
Zeiss LSM 510 META inverted
Zeiss LSM 510 META upright 
Fluorescence imaging
Delta Vision Deconvolution System
Live cell imaging chambers
Eppendorff FemtoJet system on an inverted Zeiss Axiovert 200
Flow cytometry
BD LSR Fortessa
BD FACSAria II colour cell sorter

Leicester Imaging Technologies (LITE)

Professor R A John Challiss (Head of Core Biotechnology Services)
+ 44 (0)116 229 7146

Mrs I Patel (Head of Technical Services)
+ 44 (0)116 252 5277

Advanced Imaging Facility
Kees Straatman

+ 44 (0)116 229 7085

Advanced Imaging Facility
Centre for Core Biotechnology Services
Henry Wellcome Building
University of Leicester
Lancaster Road


  • Internal and external 

Core Facility.
Immunofluorescence, live cell imaging, microinjection, FRAP/FLIP/FRET, spectral imaging, high content screening/analysis.
Data analysis and quantification (Imaris, Volocity, Huygens Essential deconvolution, ScanR/CellR, ImageJ/Fiji, NIS Elements).


Electron Microscopy Facility
Stefan Hyman
+ 44 (0)116 252 3370

Electron Microscopy Facility 
Centre for Core Biotechnology Services
Adrian Building
University of Leicester
Universityr Road


  • Internal and external 

Core Facility
Biological samples: Negative staining, Thermal metal shadowing, Ultrathin sectioning of resin embedded samples, Immuno-gold labelling, Critical point drying (CPD)


Pre-Clinical Imaging Facility
Michael Kelly
+ 44 (0)116 252 3175

Pre-Clinical Imaging Facility 
Centre for Core Biotechnology Services
University of Leicester
PO Box 138


  • Internal and external 

Core Facility


Histology Facility
Angie Gillies (Histology Manager)
+ 44 (0)116 252 3235
Karen Kulbicki (Cancer Biobank)
+ 44 (0)116 252 5842

Histology Facility 
Robert Kilpatrick Clinical Sciences Building
P.O. Box 65
Leicester Royal Infirmary


  • Internal and external 

Core Facility
Tissue collection, fixation, processing.
Paraffin wax blocks and frozen tissue sectioning.
H & E staining.
range of special stains

Flow Cytometry
Dipti Vachi 

Flow Cytometry 
Centre for Core Biotechnology Services
University of Leicester


  • Mostly internal 

Core Facility

Advanced Imaging Facility
Confocal microscopy
Leica TCS SP5 inverted
Olympus FV1000 inverted
Nikon C1Si inverted
Zeiss LSM 7 MP upright 
Fluorescence imaging
2 Nikon TE 300 inverted
2 Nikon Ti-E EM-CCD + LEDs inverted/TIRF/Screening
Olympus CellR/scanR inverted
Olympus BX61 upright with Applied Spectral Imaging's scanning platform
Bioluminescence imaging
Olympus LV200 EM-CCD
Typhoon Trio+

Electron Microscopy Facility
In-house carbon coating/metal shadowing
Leica Ultra-microtome
Balzers CPD
Hitachi S3000H SEM

Pre-Clinical Imaging Facility
Ultra-high field MRI: 9.4T Agilent preclinical MRI
Whole body fluorescence/bioluminescence: Caliper Life Sciences IVIS Spectrum
Micro-CT: Caliper Life Sciences Quantum FX
High-frequency ultrasound: VisualSonics Vevo 2100

Histology Facility
Leica ASP300 processor
Leica CM1950 cryostat

Flow Cytometry


Ian Prior
+ 44 (0)151 794 5332

Alison Beckett
+ 44 (0)151 794 5461

Biomedical EM unit
Department of Physiology
Crown Street
University of Liverpool
L69 3BX


  • Internal (80% on all instruments)
  • External commercial and external academic (20% on all)
  • DIY or full service work

Core Facility.
Probe development; high resolution imaging; image analysis; correlative light and electron microscopy.

Electron microscopes
FEI Tecnai 12 TEM with single tilt tomography holder and cryo holder. Side mount CCD.
FEI Quant 250 FEG SEM with Gatan 3View2XP
Specimen preparation
Leica EMPACT2 High Pressure Freezer with Rapid Transfer System for correlative live cell imaging.
Vitrobot plunge freezer.
2 Leica UC6/FC6 ultramicrotomes for room temp/cryo-sectioning
2 Leica freeze substitution embedding devices (AFS1, AFS2 with FSP)
Emitech 950X carbon coater
Quorum Tech Q150T sputter coater
Quorum Tech K850 critical point dryer
Gatan Digital Micrograph

Liverpool - CCI

Marco Marcello (Facility Manager)
+44 (0)151 795 5154

Violaine See (Director)
Daimark Bennett (Director)
Raphael Levy (Instrumentation development-photothermal imaging)

CCI-Centre for Cell Imaging
Institute of Integrative Biology
Biosciences Building
University of Liverpool
Crown Street
L69 7ZB


  • Internal
  • External commercial and external academic
  • DIY or full service work

Shared research facility; Assistance in image analysis and data quantification.

Confocal microscopy
Zeiss 780 invert with Picoquant FLIM-FRET module
Zeiss 510 META invert
Zeiss 510 META multiphoton invert
Zeiss 710 invert
Luminescence workstation based on a Zeiss Axiovert S 100 TV, equiped with two Hamamatsu cameras
Light Sheet
Zeiss Z.1
2 photothermal microscopes based on inverted microscopes (Zeiss Axiovert 200, Nikon T-U)
Photothermal microscopy (or LISNA) allows the detection of single gold nanoparticles

All of our systems are equiped for live cell imaging with Temp, humidity and gas (CO2 and O2) control

Cell Tracker

London, CRUK-LRI

Daniel Zicha (LM)
+44 (0)207 269 3563

Lucy Collinson (EM)
+44 (0)207 269 3416

Anne Vaahtokari (Super-resolution microscopy)
+44 (0)207 269 3511

Cancer Research UK, London Research Institute 
Lincoln's Inn Fields Laboratories
44 Lincoln's Inn Fields


  • LM - Priority given to LRI users, limited outside access
  • EM - Core Technology Facility, mainly for internal groups but with 20% open access to 3View and SECOM through MRC/BBSRC/EPSRC funding
  • Super resolution - Priority given to LRI users, limited outside access

Core facility.
Expertise in image processing and simulation.
Quantitative analysis with multi-modal microscopy.
EM - Preparation of cell biological material for TEM and SEM.
Cryo preparation techniques for biological samples (HPF, FS, Tokuyasu, freeze fracture, freeze drying, cryoEM)
Correlative Light/ Electron Microscopy (CLEM)
Volume imaging (FIB/SEM, SBF/SEM, MicroCT, NanoCT)
Super-resolution microscopy

Future requirements 
Support for developing new image processing approaches

Confocal microscopy 
LSM 510 (Zeiss) including a multiphoton system
Leica SP5
Low light level imaging systems 
Universal Imaging Metamorph,
Kinetic Imaging AQM
Molecular Devices Discovery-1
PerkinElmer UltraVIEW confocal imaging systems
Eppendorf Microinjection systems

Electron Microscopy Unit 
Electron microscopy 
FEI Tecnai G2 Sprit TEM 120kV, with tomography stage, single and dual tilt tomography holders, bottom mount Gatan Ultrascan CCD, side mount Gatan Orius CCD and FEI iCorr Integrated light microscope.
FEI Tecnai G2 Sprit TEM 120kV, with cryo stage and cryo holder, bottom mount Gatan Ultrascan CCD, side mount Gatan Orius CCD.
Zeiss Sigma VP FEG SEM with Gatan 3View
FEI Quanta FEG SEM with DELMIC SECOM integrated light microscope
Specimen preparation 
Leica High Pressure Freezer EMPACT2 and RTS
Leica GP plunge freezer
Linkam CMS196 cryo-correlative stage
RMC freeze substitution unit
2 Leica freeze substitution and low temperature embedding devices (AFS1 and AFS2 with FSP)
RMC PT-PC PowerTome ultramicrotome and CR-X cryosctioning system
3 Leica Ultracut UCT room temperature ultramicrotomes
2 Leica UC6/FC6 cryo-ultamicrotomes
Knife maker
Baltec MED020 dual gun sputter coater (carbon and carbon/platinum) and rotary shadower
Leica CPD 300 Critical Point Drier
Quorum Tech sputter coater
Gatan ion beam coater
Emitech freeze substitution K775X
Software expertise 
Gatan Digital Micrograph

Super-resolution Microscopy 
API OMX V3 structured illumination super-resolution microscope


London, CRUK-LRI

Thomas Snoeks
+44 (0)207 269 3426

In vivo Imaging Facility 
London Research Institute 
Cancer Research UK
44 Lincoln's Inn Fields


  • Primarily for LRI users but could be discussed for external users

Non-invasive in vivo imaging.
2D, 3D, 4D imaging.
Longitudinal studies for orthotopic models in oncology and hematology, normal development, stem cells, microenvironment, vascular and bone biology.
Assessment of validation of probes and contrasting procedures.
Image processing and analysis

Whole body Bioluminescence (including diffuse optical tomography and spectral unmixing) 
Caliper Life Sciences IVIS-Spectrum
Whole body Fluorescence (including epifluorescence, transillumination, tomography and spectral unmixing from UV to IR)) 
Caliper Life Sciences IVIS-Spectrum
Micro-CT (including physiological monitoring for respiratory or cardiac gating, 4D)
Skyscan 1176 in vivo scanner
Intravital microscopy of live tissues (combining multiphoton and confocal, equiped with multiparametric physiological monitoring)
Zeiss LSM710-NLO
High resolution ultrasound imaging including Doppler/power Doppler, image guided injections
VisualSonics Vevo2100

London, Imperial

Raffaella Carzaniga
+44 (0)207 594 5194

Electron Microscopy Centre
Imperial College
Exhibition Road
South Kensington
Biochemistry Building- Room 022


  • Internal and external academic research groups and commercial

Cryo-Preparation methods for TEM, TEM for Cellular Biology & Single Particles.
Image processing for Single Particles

Electron microscopy
TEM-Philips CM100 (Tungsten electron source) with film plate
TEM- FEI Tecnai 12 (LaB6 electron source); CCD camera
TEM Philips CM200 (FEG electron source); CCD camera
TEM- Philips CM300 (FEG electron source); Helium cooled-Polara Stage; CCD camera
HPF- High Pressure Freezing apparatus (EMPACT 2 with RT, Leica)
Ultramicrotomes (for ambient and low temperatures)
Parallel computer farm

London, Imperial

Dirk Dormann
+44 (0)208 383 8528

Microscopy Facility
MRC Clinical Sciences Centre
Faculty of Medicine Imperial College London
Hammersmith Hospital Campus
Du Cane Road
W12 0NN


  • Core funded by MRC, only MRC users

Core facility.
Quantitative image analysis, time-lapse

Confocal Microscopy
Leica SP1 invert
Leica SP2 invert
Leica SP5 invert with tandem scanner and FCS/FCCS
PerkinElmer UltraView Spinning Disk
Fluorescence imaging
Deltavision Spectris
Leica DMIRE2 inverted with Eppendorf microinjection system
Leica DMRB upright
Zeiss Axiovert 100S TV inverted
Zeiss Axiophot upright
Olympus SMZ-16X stereo microscope
PALM laser capture/microdissection

London, Imperial

Paul French
+44 (0)207 594 7713

Photonics Group
Physics Department
Imperial College London
South Kensington Campus


  • By collaboration

Optical Microscopy, Optical Tomography, Optical Endoscopy, Imaging Data Management and Integration, Optical Image Analysis

Future requirements
Multidisciplinary training at the interface of photonics technology and life science applications.
Long term funding for core instrumentation staff.
Tb scale optical image data management systems.
Software tools including automatic image segmentation and multidimensional analysis.

Multidimensional fluorometer
Confocal/Multiphoton Microscope, Ti-Sapphire laser or supercontinuum excitation source/FLIM/polarisation-resolved imaging
Line-scanning semiconfocal microscope with Ti-Sapphire laser or supercontinuum excitation source
TIRF microscope, multispectral imaging, FLIM/polarisation resolved imaging capability
Wide-field FLIM microscope optimised for UV excitation
Multibeam multiphoton microscope (LaVision TriMScope) with FLIM
High throughput automated optically sectioned (Nipkow) FLIM microscope
High speed Nipkow disc FLIM microscope with supercontinuum excitation
STED FLIM microscope, Leica SP2 laser scanning confocal, Ti:sapphire laser
Wide-field FLIM endoscope/macroscope system
Microconfocal FLIM endoscope
FLIM Optical Projection Tomography (OPT)

London, Imperial

+44(0)207 594 2023

FILM (Facility for Imaging by Light Microscopy)
Imperial College Exhibition Road
South Kensington / SAFB


  • Internal and external (academic and commercial)
  • DIY or assisted microscopy
  • Assay development

Core facility

Confocal microscopy
Zeiss LSM-510
Leica SP2
Leica SP5 resonant
Leica SP5 MP-Flim upright and inverted
Widefield microscopy
Incubation chambers
Automated XYZT imaging
Low and medium throughput
Image analysis


London, Imperial

Albert Busza 
+44(0)207 594 0996

Clinical Imaging Facility
Imperial College 
Hammersmith Campus
Du Cane Road
W12 0NN




London, King's

Rainer Heintzmann

Matthias Gautel

Randall Division of Cell and Molecular Biophysics
King's College London
New Hunt's House
Guy's Campus


  • Internal
  • Collaborations to apply superresolution imaging are possible
  • DIY

Superresolution Microscopy.
Facilities for structured illumination, 4pi, STED (soon), expertise in deep tissue imaging, FRET and FLIM.

Future requirements
Financial support for personnel for applying existing expertise to critical biological problems

Structured Illumination
Lecia 4Pi TCS SP2
Leica STED

London, King's

Christopher Healy
+44 (0)207 188 1795

Tissue Imaging Centre,
Dept of Craniofacial Development,
King's College London Dental Institute at
King's College and St Thomas' Hospitals,
Floor 27 Tower Wing,
Guy's Hospital,
St. Thomas St.,


  • Internal (100% on microscopes, 90% on microCT)
  • External commercial & external academic (10% on all)
  • DIY on microscopes.
  • Part or Full service work on MicroCT and OPT


Core facility.
Morphometrics, bone histomorphometry and high resolution imaging.

Confocal microscopy
Leica SP5 upright confocal microscope
Fluorescence imaging
Zeiss Axioskops with Axiocamera
Live cell imaging chambers
GE Healthcare Locus SP specimen microCT
Optical Projection Tomography
Bioptonics 3001

London, LSHTM

Theresa Ward
+44 (0)207 9272649

Liz McCarthy and Rachel Gregory (LM)
+44 (0)207 927 2063

Liz King (Flow Cytometry)
+44 (0)207 927 2294

Woolfson Cell Biology Facility
Immunology Unit
London School of Hygiene & Tropical Medicine
Keppel Street


  • Internal (90% on all instruments)
  • External academic (10%)
  • DIY or Full service work

Imaging pathogen-host interactions, at cellular level, and in whole model organisms. Includes live imaging under Cat 2 and full aerosol Cat3 containment.

Future requirements
Multiphoton for cell and in vivo imaging under containment

Confocal microscopy
Zeiss LSM 510 invert with live cell chamber and Eppendorf microinjeciton
Fluorescence imaging
Zeiss Axioplan 2 upright with CCD, epifluorescence and histology
Keyence BZ-8000 automated fluorescence microscope under Cat3 containment
Volocity software
Laser capture/microdissection
Arcturus Pixcell IIe
In vivo imaging under Cat3 containment
IVIS Spectrum and IVIS Lumina II (Perkin Elmer)
Fluorescence molecular tomography (FMT) system
Flow cytometry
Becton Dickinson LSRII
2x Becton Dickinson FACSCalibur (one under Cat3 containment)
Becton Dickinson FACSAria Fusion cell sorter (under Cat3 containment)

London, NIMR

Yan Gu
+44 (0)208 816 2621

Confocal Imaging and Analysis Lab
National Institute for Medical Research
The Ridgeway
Mill Hill


  • Core funded facility by MRC, and shared freely by users within NIMR
  • External users are charged to use the facility

Live cell imaging.
Justin Molloy's course in light microscopy.
User support, collaboration on biological imaging projects. Improving microscope performance, and development and implementation of advanced imaging techniques such as super resolution imaging, live cell/tissue imaging.

Future requirements
Imaging in tissues and whole animals, CLEM

Confocal microscopy
Leica TCS SP1 upright
Leica TCS SP2 upright
Leica TCS SP2 AOBS inverted
Leica TCS SP5 upright
Leica TCS SP5 invert
Leica TCS SP5 Multiphoton upright
PerkinElmer UltraView LCI Spinning Disk
Wide field and Fluorescence microscopy
2 X DeltaVision RT Live cell imaging microscope
Inverted DeltaVision DV2 widefield fluorescence microscope
Olympus 4 channel TIRF microscope
Olympus IX83 live imaging system
96 well plate reader
Olympus slide reader VS120 with 100 slide loader
Light sheet microscope

London, National Physical Laboratory

Alex Knight (Biotechnolgy Group)

+44 (0)208 9436308

National Physical Laboratory 
Analytical Sciences Division
Hampton Road
TW11 0LW


  • Internal
  • External commercial contract research
  • External academic collaborations welcome
Super-resolution microscopy, Single molecule fluorescence, Confocal microscopy, Adaptive optics, Instrumentation, Metrology/standards
Super-resolution Microscopy
dSTORM/PALM/Single molecule TIRF system
Structured Illumination microscopy system
Other imaging techniques available at NPL include
Confocal fluorescence microscope (Olympus FV1000), Scanning ion conductance microscopy, atomic force microscopy, raman microscopy, secondary ion mass spectrometry, optical coherence tomography, X-ray photoelectron spectroscopy, matrix assisted laser desorption ionisation mass spectrometry, scanning electron microscopy, terahertz imaging, ultrasound

London, QMUL

Andy Bushby (EM)

Gary Warnes (Flow cytometry)

Cleo Bishop (High Content Screening)

Blizard institute Advanced Light Microscopy facility
Blizard Institute
4 Newark Street
E1 2AT


  • Priority given to Blizard Institute users followed by QMUL then external
  • External commercial and academic work as required
  • DIY or full service available

Core Facility.
Super-resolution imaging
Image Processing
Tile-scanning of large areas

Confocal microscopy
Zeiss LSM 710 META upright
Zeiss LSM 510 META invert 
Andor Spinning Disk system with FRAP and EMCCD camera
Fluorescence imaging
2x Inverted Epifluoresent live cell imaging systems with environmental control and scanning stage
2x Upright Epifluorecent systems
Lasercapture microdissection
Stereology with histopathology camera
Macroscope with colour CCD camera

Metamorph, Imaris, ImageJ + Fiji, Matlab, Cell Profiler

Electron microscopy

Carried out by the Nanovision centre
Flow cytometry
Carried out by the Flow cytometry facility
High Content Screening
InCell 1000 imaging system

London, Royal Veterinary College

Andrew Hibbert
+44 (0)207 468 5257

Imaging Suite Microscopy Facility
Royal Veterinary College
Royal College Street


  • Used internally by researchers including BSc project students, post-graduates and research staff
  • Available to external academic or commercial users
  • Compulsory training and further assistance provided as required

Core Facility
Image Processing, Image analysis. Teaching - Individual training and courses 

Confocal microscopy 
Zeiss LSM 510
Leica SP5 with motorised stage and live cell imaging chamber
Fluorescence imaging 
Leica DM4000 with Zeiss mRM camera
Leica DMRA2 with Zeiss mRM camera
Leica DMIRB inverted microscope with Leica DC500 camera
Zeiss ICm1 camera
Leica DMI6000 with motorised stage and DFC350FX camera
Transmitted light
Leica DM4000 with Leica DC500 camera (Bright Field, Phase contrast)
Zeiss Axiovert 135 with Leica DC500 camera (Bright Field, Phase contrast, DIC)
Volocity plus custom programs created in house
Flow cytometry
Available through separate facility 

London, UCL

Jeremy Hebden
+44 (0)207 679 0280

Biomedical Optics Research Laboratory
Department of Medical Physics & Bioengineering
University College London
Malet Place Engineering Building


  • Highly variable, depending on demand

Functional optical tomography of the neonatal brain. Real-time optical imaging of seizure in infants, including associated haemodynamic activity in the deep brain.

In vivo imaging systems
32-channel time-resolved optical tomography system
32-source, 16-detector optical topography system
IMRA dual-wavelength fibre laser
Fianium supercontinuum laser
Ti:S picosecond las

London, UCL

Andrew Vaughan (LM)
+44 (0)207 679 7904

Jemima Burden (EM)
+44 (0)207 679 3650

MRC Laboratory for Molecular Cell Biology Unit
University College
Gower Street


  • Mostly internal
  • Small number of external users; about one or two a year

Core facility.
Collaboration and development of techniques, image processing and analysis

EM facility - Preparation cell biological material for TEM and SEM. Cryo preparation techniques for biological samples (HPF and FS, and Tokuyasu)

CLEM, 2D and 3D

Future requirements
Tools for image analysis and data processing

Light Microscopy Facility
Super-resolution microscopy
Coming soon! - Leica TCS STED 3X (single depletion laser, no 3D capability) with DMI6000 inverted microscope, HyD detectors, motorised stage and Life Imaging Technologies Cube incubator
Coming soon! - Zeiss Elyra PS.1 with Axio Observer inverted microscope
Coming soon! - Nikon N-STORM system with TiE inverted microscope, TIRF and high speed wide-field imaging

Confocal microscopy 
Leica TCS SP5 with DMI6000 Inverted with motorised stage and Pe-Con stage-top incubator
2 Leica TCS SPE with DM2500 upright microscopes and optional Warner Instruments perfusion chamber and Okolab dipping lens incubation system
Leica TCS SPE with DMI4000 inverted microscope and motorised stage
Olympus Fluoview FV1200 with IX83 inverted microscope, two GaAsp detectors, 405nm PicoQuant pulsed ablation laser coupled to SIM Scanner and Tokai-Hit incubation equipment
Bio-Rad Radiance 2100 with Nikon E800 upright microscope and GaAsp detectors
Perkin Elmer Ultraview Vox spinning disc with Nikon TiE inverted microscope, Photokinesis Unit for photo-bleaching and photo-activation, Solent Scientific environmental chamber, Prior stage and piezo focus
Time-lapse microscopy
Zeiss Axio Observer with LEP stage and transmitted light shutter, environmental chamber for time-lapse imaging, Volocity software
Zeiss Axiovert 200M with LEP stage and shutter, environmental chamber for time-lapse imaging, Volocity software
Fluorescence microscopy
3 Zeiss upright and 2 Leica inverted microscope/camera systems using Openlab or Volocity capture software
Software Packages
Volocity licence server with 500 core licences and 3 copies of the Restoration, Quantitation and Visualisation packages, Metamorph, Huygens, AutoQuant, Imaris.
64-bit windows 7 PCs.
Support for Leica LAS AF and Fiji/Image J.

Electron Microscopy Facility
Electron microscopy
FEI Tecnai G2 Sprit TEM 120kV, with tomography stage and holder, side mount SIS Morada 11mpx digital camera
FEI-Philips CM10 TEM with side mount Gatan 1kx1k digital camera
Specimen preparation
Leica High Pressure Freezer EMPACT
2 Leica AFS freeze substitution and low temperature embedding devices (1 AFS1, 1 AFS2 with FSP)
Leica Ultracut E room temperature
Leica Ultracut UCT room temperature
Leica Ultracut UCT, FCS cryo
Leica Knife maker
Baltec Med020 dual gun sputter coater (carbon and carbon/platinum), rotary shadower, freeze drier, glow discharger
Biorad Critical Point Drier 3000
Inspect 3D

London, UCL

Chris Thrasivoulou
+44 (0) 207 670 0904

Tim Robson

Danial Ciantar

Jane Pendjiky

Centre for Cell & Molecular Dynamics
UCL Faculty of Life Science
Imaging Centre (Biosciences)
5th Floor
Rockefeller Building
21 University Street


  • All users welcome (Internal and External)
  • Flat rate for all confocals £20 per hour for all users
  • Overnight rate £10 per hour

The unit has four experienced members of dedicated staff who are on hand at all times. Full training of all users at no extra cost. Free consultancy service available for help with experimental design and imaging, trouble-shooting requirements.

Future requirements
New microscopes will be added in the future to cater for research needs. This will include spinning disk confocals, resonant scanning confocals and Multiphoton-OPO systems for Second and Third Harmonic Generation microscopy that this unit is developing.

Confocal microscopy
Leica SP2 UV upright multiphoton, live-cell imaging
Leica SP2 fixed-stage upright, multiphoton, live-cell imaging
Leica SP8 upright multiphoton OPO, live cell imaging
Leica SP8 upright confocal, live cell imaging
Leica SP2 upright, single photon system
Leica SPE (x2) upright, single photon system, live-cell imaging
Leica SPE inverted, single photon system, live-cell imaging
Olympus Fuoview 1000, Sim-Scan, TIRF single photon system, live-cell imaging, ZDC
Zeiss 510 upright/invert multiphoton, live-cell imaging
Zeiss 510 META UV-VIS, inverted single photon system
Zeiss 510 META inverted VIS, inverted single photon system
Zeiss 700 inverted, single photon system

Fluorescence Wide-Field Microscopy
Molecular Devices ImageXpress Micro XL widefield high content microsocpe
Zeiss AxioScan Z1 slide scanner


London, UCL, Centre for Advanced Biomedical Imaging

Mark Lythgoe
+44 (0)20 7679 6164

Centre for Advanced Biomedical Imaging
Paul O'Gorman Building
University College London
72, Huntley Street


  • Internal and External commercial & external academic available
  • DIY or Full service work
Core Facility; In vivo Preclinical Imaging; In vivo Tumour, Cardiac and Neuro-Imaging; Optogenetics; Magnetic nanoparticles; Probe and MRI contracts agent development; Multimodal Image analysis; Brain atlas generation; In Vivo Experimental models (eg stroke and myocardial infarction)
In vivo Preclinical Imaging:
9.4T Magnetic Resonance Imaging: Agilent Technologies
Photoacoustic Imaging: based upon the use of Fabry Perot polymer film sensing interferometers
Ultrasound: A Vivid 7 Dimension (GE Healthcare)
SPECT/CT: Bioscan system
Bioluminescence and fluorescence imaging system: Biospace Lab PhotonIMAGER™ 
CT-guided in vivo irradiation:  Xstrahl system

London, UCL, ICH

Dale Moulding
+44 (0)207 905 2786

Confocal Microscopy Core Facility
UCL Institute of Child Health
30 Guildford Street


  • All users welcome (Internal and External) academic and commercial.
  • Flat rate for all confocals £20 per hour for UCL users, overnight rate £10 per hour (please contact facility manager for external rates).
  • DIY or full time support if required.


Image acquisition of fixed and live samples with OpenLab, Volocity, Leica and Zeiss confocal softwares.
Image processing and quantitative analysis with Volocity, ImageJ and CellProfiler.
Help for manuscript preparation: Photoshop, Illustrator, InDesign

Confocal microscopy
Leica SP2 UV-VIS upright, multiphoton excitation, live-cell imaging (inverted stand available), FRAP, FRET
Zeiss 710 UV-VIS, inverted single photon system, live-cell imaging, FRAP, FRET, spectral imaging
Widefield microscopy
Zeiss Axiovert 135 Fluorescence widefield microscope, live cell imaging (OpenLab, Volocity acquisition software)

London, UCL, WIBR

Robert Francis
Microscopy and FACS (Applications specialist)
Tel: +44 (0)207679 7600 (ext: 47600)

George Chennell
Applications Specialist - Laser Micro-Dissection / Confocal Microscopy/ Live Cell Imaging/ Seahorse Bioanalyser
Tel: +44 (0)207679 6757

Scientific Support Services
UCL Cancer Institute and Wolfson Institute for Biomedical Research
The Cruciform Building
Gower Street
UCL London


  • Internal (75% on all instruments)
  • External commercial and external academic (25% on all instruments)
  • DIY or full service work


Core facility; software analyses; High resolution imaging

Confocal microscopy
Leica TCS SP
PerkinElmer UltraView Volocity Acquisition Spinning Disk
Fluorescence microscopy
Zeiss CellObserver Live Cell Imaging Microscope
Zeiss AxioImager A1 fluorescent microscope
PALM laser capture/microdissection
Flow cytometry
Beckman Coulter CyAn flow cytometer
Beckman Coulter MoFlo high-speed sterile cell sorter
Volocity Visualisation and Quantification


Peter March
+44 (0)161 275 1571

University of Manchester Bioimaging Facility
Faculty of Life Sciences
Michael Smith Building
Oxford Road
M13 9PT


  • Internal (95% on all instruments)
  • External commercial & external academic (5% on all)
  • Mainly DIY or piloted

Expertise in live cell imaging and particle tracking.
High resolution imaging.

Future requirements
Faster live imaging and in vivo animal imaging

Confocal microscopy
Leica SP5 Tandem Head (inverted)
Leica SP5 MP (upright)
Leica SP2 MP (inverted)
Nikon C1 (upright)
Nikon C1/TIRF (inverted)
Nikon Swept Field Confocal (inverted)
Widefield microscopy
API Delta Visions
MetaMorph based live cell system with FRAP
Image Pro live cell imaging systems
BD Pathway 855 high throughput system
PALM laser microdissection

Manchester, CRUK

Steve Bagley
+44 (0)161 446 8631

Advanced Imaging and Flow Cytometry Facility  
Cancer Research UK Manchester Institute
The University of Manchester
Wilmslow Road
M20 4BX


  • CR UK 50%
  • Manchester Cancer Research Centre 50%

CR UK Core Facility
Super resolution imaging
Histological whole slide image analysis
Flow cytometry and imaging cytometry
High Content Scanning and analysis

Super Resolution Microscopy
Leica GatedSTED and multiphoton imaging

Confocal microscopy with full environmental control
Leica (SP8 MP CSU)
Leica Macro-Confocal TCS LSI
Roper Spinning disk confocal

Flow Cytometry Sorters
BD Influx with a class II enclosure
BD Aria III with a class II enclosure
BD Aria II
BD Jazz

Flow Cytometry Analysers
Amnis ImageStream II
BD Fortessa x20
BD Calibur x 2

Widefield microscopy with full environmental control
API Deltavision Core
Low light imaging system with an Andor iXon 888 camera & a CRI Nuance 500-1000nm spectrophotometer
Time lapse with an Andor iXon 888 camera

Histology scanning (virtual microscopy) 
PerkinElmer Vetra, spectrophotometric imaging system, brightfield and fluorescence
Leica SCN400, brightfield illumination
3D-Histech 250scan, fluorescence LED illumination for imaging up to five fluorescence labels

High Content Screening
Thermo Cellinsight

Miscellaneous equipment
Phosphorimaging Bio-Rad Pharos FX plus systems (x2)
Seahorse XFe Extracellular Flux Analyser

Definiens Tissue Studio: image analysis of histological data sets
Definiens Image Miner: for drawing together measurement and statistics from image analysis
IDEAS: multi-spectral defining and analysis for the PerkinElmer Vectra
FlowJO: viewing and analysis of flow cytometry data
Imaris: image processing and analysis of multi-dimensional data sets
Huygens: image deconvolution software for multi-dimensional data from a variety of sources

Newcastle upon Tyne

Alex Laude (Manager Bio-Imaging Unit)
+44 (0)191 246 4860

Kath White (Manager EM Research Services)
+44 (0) 191 2086966

Bio-Imaging Unit
EM Research Services
Newcastle University Medical School
Framlington Place
Newcastle upon Tyne


  • Core Facility
  • Internal on all instruments
  • External commercial & academic on application
  • DIY or full support service
  • Proof of principle / developmental studies undertaken
  • Training
  • Cat 2 tissue culture facilities (Bio-Imaging)

    Multidimensional image acquisition, wide field, confocal, live cell imaging, FRET, FRAP, TIRF, super resolution microscopy N-SIM / N-STORM, TEM, SEM, sample preparation

    Future requirements
    FLIM, FCCS, advanced image processing, correlative-LM/EM, 3-view

Electron microscopy
S240 SEM

Sample Preparation
Leica EM UC7 ultramicrotome
Leica EM AC20 stainer
Baltec critical point drier
Edwards coating unit - carbon
Polaron coating unit - gold

Light Microscopy
Wide field microscopy
Zeiss AxioImager Z2 with Apotome (upright)
Nikon Ti with Oko-Lab live-cell enclosure (invert)
Nikon T2000 (invert)

Confocal Microscopy
Point Scanning
Leica SP2 UV AOBS with Multi-Photon (upright)
Nikon A1 (x2) with resonant scanner & spectral detector. Oko-Lab live cell enclosure, CO2 & O2 control (invert)
Spinning Disk
Nikon Ti, CSU10, Oko-Lab live cell enclosure (invert)
Zeiss Cell Observer, CSU X1, live cell enclosure (invert)
Andor Revolution XD, CSU x1, live cell chamber (invert)

Nikon Ti with Oko-Lab live cell enclosure (invert)

Nikon BioStation CT (invert)

High content
BD Pathway 855

Super Resolution

In vivo Imaging
Xenogen IVIS 200

Photometrics Evolve 512 (EM-CCD), Photometrics QuantEM (EM-CCD), Hamamatsu Orca ER (CCD), Nikon DS-Qi1 (EM)

Nikon Elememts, PE Volocity, Bitplane Imaris, Image Pro

Norwich, John Innes

Kim Findlay
+44 (0)1603 450668

Grant Calder
+44 (0)1603 450298

Peter Shaw
+44 (0)1603 450330

BioImaging Facility
Department of Cell and Developmental Biology
John Innes Centre
Norwich Research Park


  • Internal on all instruments
  • External commercial & external academic (on application)
  • DIY or Full service work

Expertise in plant cell biology, in vivo imaging.
SIM and STORM super-resolution, GFP technology, high resolution cryo-SEM, general TEM sample prep including HPF and imaging

Future requirements
Image analysis, especially tools for shape recognition in organisms

Confocal microscopy
Zeiss LSM 780 upright
Leica SP5 (II) upright
Zeiss Elyra PS1 invert
Andor Revolution XD Spinning disk invert
Visitech QLC100 Spinning Disk Upright
Fluorescence imaging
Leica DFM6000 upright
Zeiss Axio Observer.Z1 invert
Leica M205FA stereo
Leica Fluo III stereo
Zeiss Lumar v2 stereo
CCD imaging
Live cell imaging chambers
Electron microscopy
FEI Tecnai 20 TEM
FEI Nova Nano SEM 450 FEG SEM
Zeiss Supra 55VP FEG SEM
GATAN Cryosystems on both SEMs Deben Coolstage for Zeiss SEM
Leica HPM100 high pressure freezer
Leica AFS2 freeze substitution 
Gatan Impact freezer

Norwich, UEA

Paul Thomas
+44 (0)1603 592196

Henry Wellcome Laboratory for Cell Imaging
School of Biological Sciences
University of East Anglia


  • Full access to external users, though internal users get priority.
  • DIY or Full service work

Core Facility.
Live-cell imaging (ion measurements and cell tracking); Image analysis (Intensity and ratiometric analysis, cell tracking, deconvolution, co-localization).
Offers a 3-day course in live-cell imaging.

Confocal microscopy
Zeiss LSM 510 META invert/upright
Leica TCS SP2 invert
Multiphoton microscopy
LaVision Biotec TriM Scope II with TCSPC
FLIM capability (invert/upright)
Fluorescence imaging
Zeiss Axiovert 200M with environmental chamber optimized for single-cell imaging with LED light source and Apotome.
Zeiss Axiovert 200M with environmental chamber optimized for larger samples and multi-well plates.
Zeiss Axioplan 2ie for fixed specimens
Zeiss SV11 stereomicroscope

Nottingham, School of Life Sciences Imaging (SLIM)

Tim Self
+44 (0)115 8230090

Cell Signalling Research Group 
School of Life Sciences
Medical School
University of Nottingham
Queen's Medical Centre


  • Instruments are open to internal access
  • External access available. Please contact Tim Self

Live cell pharmacology, novel ligands.

Future requirements
Analysis algorithms for HCS approaches

Confocal Microscopy
Zeiss 880 with environmental control
Zeiss LSM710 with perfusion and environmental control
Zeiss LSM700 with environmental control
Zeiss LSM510 with perfusion and environmental control
Zeiss Exciter
Leica SP2 with environmental control
Super Resolution
Zeiss 780 with Elyra PS1 super resolution system and environmental control. SIM, 3D PALM, STORM, Widefield, confocal, TIRF capability
Zeiss NLO Confocor3 with FLIM and perfusion
Deconvolution & TIRF
Zeiss TIRF system with environmental control, EMCCD and Flash4 CMOS cameras
Deltavision Elite/TIRF with environmental control, EMCCD and Coolsnap cameras
Wide Field
Leica DMIRE2
Leica DMRB
Numerous fluorescence, stereo and dissecting microscopes
Zeiss 880 32 GAsP
Confocor 3 (on NLO)
Confocor 2 (on 510)
Myography/edge detection
DMT myography/edge detection
Cairn edge detection
High Content Screening
MDC Ultra confocal plate reader & PAA robot
MDC Micro WF plate reader with environmental control
High Throughput Screening
MDC Flexstation 1
MDC Flexstation 3
Electron microscopy
FEI BioTwin 100kV LaB
JEOL 1010 100kv
Ultramicrotomes x3
Microtomes x3
Cryostats x2
Automatic embedding station
Critical point dryer
Sputter coater

Nottingham, Nottingham Trent University

Gordon Arnott
+44 (0)115 848 3182 (office)

Imaging Facility
Nottingham Trent University
Clifton Campus
NG11 8NS


  • Internal on all instruments
  • External contracted work by appointment

Confocal microscopy 
Leica SP5ii (Inverted, with live cell imaging & resonant scanner)
Fluorescence microscopy 
Olympus BX-51 upright + Olympus DP-71 camera
Zeiss Axioskop 2 upright with fixed stage + Hamamatsu Orca 05G camera
Leica DMIRBE inverted with motorised stage + Hamamatsu Orca 05G camera
Leica DMREB upright with motorised stage + Hamamatsu Orca 05G camera
Widefield microsopy
Olympus BX-51 upright + Olympus DP-71 camera
Electron microscopy 
JEOL JSM-840A SEM + Oxford EDS
JEOL2010 200Kv TEM + Oxford EDS
High content
Molecular Devices MetaExpress Micro

The Open University

Heather Davies
+44 (0)1908 653392

The Open University
Electron Microscopy Suite
Walton Hall
Milton Keynes

Biomedical Research Network


  • Internal academic (university wide)
  • External commercial and academic
  • Can be used as DIY or with technical help
Electron microscopy
JEM 2100 - a 200kV LaBTEM from JEOL. High resolution EM with a high tilt polepiece, STEM and EDAX EDS detector.
Zeiss Supra 55VP - Analytical FEGSEM with variable pressure mode, Oxford EDS and EBSD capabilities.
JEM 1400 - a 120kV TEM from JEOL. High contrast TEM with an AMT digital camera.
JEM 1010 - a 100kV TEM from JEOL with an AMT digital camera.
Extensive preparation facilities including ultramicrotomy and freeze substitution.

Oxford, Micron Advanced BioImaging unit

Ian Dobbie
+44 (0)1865 613323

Micron Advanced BioImaging Unit
Department of Biochemistry,
University of Oxford,
South Parks Road,


  • All instruments are open to internal University of Oxford users
  • External users are allowed, please contact us for more details

Confocal microscopy
2 PerkinElmer Spinning disks with FRAP units and environmental chambers for live cell imaging. One of these instruments has micro-injection facilities. 
Olympus FV1000 LSM with lifetime detection.
Olympus FV1200 with 350nm laser for DNA damage experiments.
Zeiss LSM780 with live cell environmental control.
Widefield Fluorescence imaging
DeltaVision Core.
DeltaVision Elite with live cell incubation etc and EMCCD camera.
Light Sheet Microscopy
Stelzer built mDSLM system.
Zeiss Z1 with dual illumination and two cameras, live cell heating etc.
Super-resolution systems
OMX V2 system for fixed structured illumination, or fast live cell widefield.
OMX V3-Blaze for fast SIM in fixed or live samples with SDK for novel protocols eg SIM FRAP, Zramp for extremely fast 3d live cell widefield imaging (>10 Z stacks per second in 3 colours).
Bespoke PALM/TIRF setup for single molecule tracking, PALM/dSTORM experiments.

Oxford Brookes

Louise Hughes 
+44 (0)1865 483290

Department of Biological and Medical Sciences
Oxford Brookes University
Gipsy Lane


  • Unit services the University
  • External users welcome
  • Training available
  • Oxford Microscopy Consultancy offers a full microscopy service (

Live cell imaging, electron tomography, cryo-preparation,SBFSEM and SEM

Future requirements
Spinning disc confocal, TIRF

Confocal microscopy
Zeiss LSM 510 META upright
Zeiss LSM 510 invert
Zeiss Axioplan +CCD
Electron Microscopy
Zeiss Merlin VP compact SEM with Gatan 3View system
Hitach H-7650 120 kV tomographic TEM
Hitachi S-3400N variable pressure SEM
Preparative equipment
Baltec HPM 010 high pressure freezer
RMC PowerTome PC with CR-X cryo attachment


Flow cytometry
Becton Dickinson FACSCalibur cytometer

STFC Central Laser Facility, Research Complex at Harwell

David Clarke
+44 (0)1235 567035

Octopus Imaging Cluster Central Laser Facility
Science & Technology Facilities Council
Rutherford Appleton Laboratory
OX11 0QX


  • Via peer-review panel for external and internal users
  • Approx 80% of scheduled time for long-term (>1 year) programmes, and 20% for proof-of-principle work
  • Additional access for users of other facilities (Diamond Light Source, ISIS, Research Complex at Harwell)
  • Commercial access also available

Core Facility; Single molecule techniques, including in live cells; single molecule and ensemble FRET; FLIM/PLIM; super resolution (STORM/PALM, STED, SIM); laser tweezers/trapping; development of advanced laser microscopy instrumentation.

Central laser cluster (ns, ps, fs and steady state lasers UV-near IR) feeding the following microscopy stations:

Super-resolution microscopy
Leica SP8 gated STED microscope with 50nm lateral resolution. Includes super-resolution fluorescence lifetime imaging (FLIM) and fluorescence correlation spectroscopy (FCS), with 80 nm resolution.

Zeiss Elyra PS1 microscope for structured illumination microscopy (SIM). Can image multiple optical sections through the depth of a cell. A 2 μm stack with 16 slices at full frame (1280 x 1280 pixels) and 50 ms integration time can be imaged in 14.6 seconds.

Localization microscopy: Zeiss system for 2D STORM with epi or TIRF illumination (up to 3 wavelengths simultaneously). Zeiss Elyra PS1 with STORM/PALM capability. Vutara SR-350 offering 2 colour biplane imaging with sCMOS detectors for fast 3D super-resolution microscopy

Total internal reflection fluorescence (TIRF) and Single molecule microscopy
Multidimensional single molecule imaging and tracking (up to 5 wavelengths simultaneously) in live mammalian, plant, and bacterial cells.

Single molecule microscopy for measuring inter/intra-molecular distances in isolated molecules and fixed cells: one in the 10-80 nm range using single molecule localisation with photobleaching (with 10 nm resolution) and the second using alternating laser excitation (ALEX) and single molecule Förster Resonance Energy Transfer (FRET).

Confocal microscopy
 (multiphoton and single photon) with the following techniques implemented:
Fluorescence and phosphorescence lifetime imaging (FLIM and PLIM) Second-harmonic imaging microscopy (SHIM)
Fluorescence Correlation Microscopy (FCM)
Single molecule confocal ALEX-FRET system.

Laser trapping/tweezers
Two systems: one stand-alone system and one in combination with imaging techniques including TIRF microscopy, FLIM, and Raman spectroscopy.

Raman microscopy including tip-enhanced Raman spectroscopy (TERS).

Support Equipment
Including fully equipped biochemistry and cell culture preparation laboratories, fluorimeters and spectrophotometers, -80oC freezers, liquid nitrogen storage facilities, labelling technology (chemical and molecular biology), computing infrastructure, and access to mass spectrometry, scanning and transmission electron microscopy (Research Complex at Harwell).

Oxford, MRC Harwell

Jeremy Sanderson
+44 (0)1235 84 1051 (office)
+44 (0)1235 84 1181/1037 (labs)

Mammalian Genetics Unit
MRC Harwell
Harwell Science and Innovation Campus
OX11 0RD


  • Internal on all instruments
  • External contracted work by appointment
Confocal microscopy
Zeiss 710 Laser Scanning Confocal Microscope
Zeiss 700 LSM Confocal Microscope
Multi-photon microscopy
Zeiss 710 NLO on upright Axio-examiner Z.1 + BiG GaAsP detectors (on LSCM above)
Fluorescence microscopy
Olympus IX-81 inverted + XM10 camera
Olympus BX-41 upright + CFW1312M camera
Zeiss Axio-Observer Z1 with ApoTome2 and VivaTome
Leica DM2500 + Hamamatsu 9300 fast-frame camera
Widefield microsopy
Zeiss Axio-Observer Z1 inverted + AxioCamHRc camera
Olympus BX-51 upright + DP25 digital colour camera
Electron microscopy
Image analysis
Perkin-Elmer Volocity 6


Errin Johnson (EM Facility Manager)
+44 (0)1865 285742

Sir William Dunn School of Pathology
University of Oxford
South Parks Road


  • Internal (University wide)
  • External academic on application
  • Free training given for DIY work
Core Facility, wide range of specimens (including plants), live-cell imaging, FLIM, TEM, SEM, EM standard and cryo-preparation, electron tomography, 3View and 3D SEM imaging
Confocal microscopy
Zeiss 510 META inverted with temperature and humidity chamber and 5LIVE system
Olympus FV1000 with Becker and Hickl FLIM system
Olympus FV1200 with UV laser and live cell imaging system
Fluorescence microscopy
Zeiss Axioplan 2e with CCD
Zeiss Axiovert 200 with CCD 
Nikon 'Coolscope' slide scanner
Full histology service and training also available at the Dunn School 
Electron microscopy 
FEI tecnai 12 120kV TEM with Gatan US100 CCD camera
Fischione dual-axis tomography holder
Zeiss Merlin Compact Field Emission Gun SEM with Variable Pressure mode and 3View module for high resolution 3D imaging using serial block face sectioning
Specimen preparation 
Leica KMR3 knifemaker 
Leica UC7 & Reichert UCE ultramicrotomes
Leica EMPACT2 high pressure freezer
Leica AFS1 & AFS2 freeze-substitution units
Leica UCS cryo-ultramicrotome
Touismis AutoSamdri critical point dryer
Quorum Technologies Dual ES Coater
Edwards Auto306 Coating unit
Fluorolog-3 Spectrofluorimeter
Flow cytometry facility also available at the Dunn School

Pirbright, Institute for Animal Health

Pippa Hawes
+44 (0)1483 231103/231026

Institute for Animal Health
Ash Road
GU24 0ND


  • Internal (mainly)
  • External academic or commercial collaboration possible

Core Facility, containment microscopy
Cell biology and virology
Confocal and transmission electron microscopy
Live cell confocal microscopy at SAP04 containment

Future requirements
TIRF, multi-photon, image analysis, full data management system


Confocal microscopy
Leica SP5 (upright and invert)
Leica SP2 (upright)
Leica SP2 (invert, for live cell imaging at SAP04 containment)
Vibrating microtome, cryostats, LMD's, fluorescent microscope, camera systems
Electron microscopy
FEI Tecnai 12 120kV TEM, with Tietz F214 camera
Cyro-TEM and dual axis tomography holders
Leica CPC plunge freezer
Leica HPM100 HPF
Leica AFS, AFS2
Leica UC6 ultramicrotome
Leica UC7 cryo-ultramicrotome
Inspect 3D, IMOD, Amira



Peter Harris 
+44 (0)118 378 6118

Centre for Advanced Microscopy
J.J. Thomson Physical Laboratory
University of Reading
RG6 6AF 


  • Internal on all instruments
  • External work welcome
  • DIY or full support service

Dedicated staff to provide support and training for each microscope. Expertise in cryo-SEM, ESEM and high resolution TEM. Also EDX and WDX analysis and microtomy. Expertise in applying all forms of microscopy to nanomaterials and polymers as well as biomaterials.

Electron Microscopy
FEI CM20 200kV TEM equipped with EDX and AMT digital camera
Jeol 2010 200kV high resolution TEM equipped with AMT digital camera
FEI Quanta 600 variable pressure SEM with ESEM and cryo capability.
Extensive EM preparation facilities including gold, chromium and carbon coaters, critical point dryer and microtomes.


Smita Kurup 
+44 (0)1582 763 133

Rothamsted Bioimaging
PPM Department
Rothamsted Research


  • Internal and external, academic research groups and commercial
  • Independent or full service work

Core Facility.
Plant cell biology.
Live cell microscopy, sample preparation for sectioning, sectioning, cryoSEM, EDS, high resolution TEM, electron tomography and image analysis.

Future requirements
In vivo imaging and image analysis tools

Confocal microscopy
Leica TCS SP1 inverted
Widefield & fluorescence microscopy
Zeiss upright and inverted microscopes with CCD imaging both in colour and monochrome
Timelapse capabilities
PALM laser capture/microdissection
Leica M205 FA automated stereomicroscope
Electron microscopy
Jeol 6360 LVSEM with Gatan Alto 2100 cryosystem, Deben coolstage and Oxford EDS
High resolution Jeol 6700F FEG-SEM with Gatan Alto 2500 cryosystem and Oxford EDS
Jeol 2011F TEM with Gatan dual-axis holder for tomography, Gatan cryoholder and Oxford EDS
Image Analysis
Amira, MetaMorph, ImageJ


Colin Gray
+44 (0)114 2261234

Light Microscopy Core Facility
Faculty of Medicine, Dentistry and Health
The University of Sheffield
Beech Hill Road
S10 2RX



  • Internal on all instruments
  • External commercial & academic on application
  • DIY or full support service work

Core facility, multiphoton, time lapse imaging


Confocal microscopy
1 Inverted multiphoton Zeiss LSM510 META with a Coherent Chameleon MP laser and environmental control
1 Upright multiphoton Zeiss LSM510 META with a Coherent Chameleon MP laser with dipping objectives and environmental control
Becker and Hickl FLIM
Live cell imaging
Leica AF 6000LX with full environmental control
Fluorecence microscopy
Leica DMI 4000B
Image Processing
Central server with remote access and 2 offline workstations




Darren Robinson
+44 (0)114 2224682

Light Microscopy Facility
University of Sheffield
Alfred Denny Building
Western Bank
S10 2TN


  • Internal (90% on all instruments)
  • External commercial & external academic (10% on all)

Core facility

Confocal microscopy
Olympus FV1000 Upright with SIM scanner
PerkinElmer UltraView Spinning Disk
Nikon A1 invert with TIRF
Widefield imaging
Deltavision RT with quantifiable laser module
Nikon dual cam system
Additional techniques
Structured Illumination microscopy
Localisation microscopy
Light Sheet microscopy


Nicola Green
+44 (0)114 2223932

Kroto Research Institute Confocal and Two-Photon Imaging Facility
Kroto Research Institute
North Campus
University of Sheffield
Broad Lane
S3 7HQ


  • Internal
  • External commercial & external academic
  • DIY or with Experimental Officer support

Core facility; Two-photon imaging of biological tissue

Confocal microscopy
Zeiss LSM 510 META NLO invert with environmental chamber
Zeiss LSM 510 META NLO upright (with in house modifications for time resolved emission microscopy)
Fluorescence imaging
Zeiss epifluorescent inverted microscope with environmental chamber


Anton Page
+44 (0)23 8079 4815

Biomedical Imaging Unit
Level B South Block MP12
General Hospital
SO16 6YD


  • All users welcome (Internal and External)
  • Diagnostic work 50% (internal & external)
  • Academic 50% (mostly internal).
  • Independent or full service work.
  • Commercial service available.
  • Free instrument training of all users.
  • Consultancy service to help with experimental design, imaging and analysis

Joint University & NHS Trust core facility.
The Unit has 5 experienced full time staff supporting research and diagnostic work.
Staff support on hand at all times.

Confocal microscopy, live cell imaging, TEM, SEM, 3D microscopy, x-ray microanalysis, diagnostic electron microscopy (renal, nerve, muscle etc), national centre for the diagnosis of primary ciliary dyskinesia.
Art-science collaborations
Artist in residence
One week TEM course (IBMS accredited)
One week advanced LM course (IBMS accredited)
Trainee biomedical scientists specialising in electron microscopy (graduate day-release)

Future requirements
Correlative light & electron microscopy.
High throughput microscopy
Expanded 3D processing capability
Increased data storage capability

Confocal microscopy
Leica SP2
Leica SP5 (Inverted, with live cell imaging & resonant scanner)
Electron microscopy
FEI Tecnai 12 TEM (with XRM)
Hitachi H7000 TEM
FEI Quanta 250 FEG equiped with Gatan 3View for high resolution 3D microscopy
FEI Quanta 200 SEM (with XRM, variable pressure & environmental modes)
Full TEM & SEM preparation facilities including cryosectioning (all independent or full service)
Fluorescence imaging
LaVision light sheet microscope for 3D visualisation of 2-10mm specimens
Olympus IX 81 (with live cell imaging)
Zeiss Axioskop 2
Leica DM IRBE (with live cell imaging)
Leica DM RBE
Light microscopy
Olympus DotSlide with remote access
High speed video microscopy (with live cell imaging)
2D and 3D Image analysis and processiong
SIS iTEM, SIS Cell^P, Zeiss KS software, Aviso, Amira, Reconstruct


Mark Willett

+44 (0)2380 59 4235 

Imaging and Microscopy Centre
School of Biological Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
SO17 1BJ


  • Open to all users (academic, non-academic)
  • Internal (85% on all instruments)
  • External commercial, external academic & external public (15% on all instruments)
  • DIY or full service work
Modern Core Facility with containment level 1 and 2 labs.
Live cell imaging, Multiphoton microscopy, Fluorescence correlation spectroscopy (FCS), Electrophysiology.

Future requirements
Super-resolution fluorescence microscopy.

Confocal microscopy
Leica TCS SP2 FCS multiphoton upright with environmental chamber and stage-top incubator
Zeiss LSM 510 META upright with fixed stage and UV laser
Fluorescence imaging
Zeiss Axiophot 2 upright
Zeiss Axioskop 2 upright with fixed stage
Zeiss Axiovert 200 invert
Leica DM IRB invert with Leitz micromanipulators
Live cell imaging chambers
Axoclamp-2A amplifier
Axopatch 200B amplifier
Preparation room
Wolf Lab. Galaxy S Incubator
Microbiological Safety Cabinet Class II
Leica MZ 16F stereomicroscope


Ian Sinclair (Director)
+44 (0)23 8052 5095

Philipp Schneider (Biomedical Imaging)
+44 (0)23 8059 4640

Thomas Blumensath (Image Processing)
+44 (0)23 8059 3224

Tiina Roose (Bio-physical Simulation)
+44 (0)23 8059 2374

μ-VIS X-ray Imaging Centre 
Building 5 (Eustice)
Highfield Campus
University of Southampton
SO17 1BJ


  • Internal and external academic scanning via web form:
  • External commercial scanning and consultancy
  • Proof of principle scans
  • Independent and/or full support service
  • Instrument training for all users and further assistance provided where required
  • Consultancy meetings for experimental design, imaging and analysis
  • Technical and academic support through dedicated staff for each μCT scanner and for all core application areas, respectively

Core facility;
Micro-computed tomography (μCT);
In situ 4D imaging using condition devices (eg. cryostage, loading rig or hydrostatic pressure cell);
Multiscale 3D imaging (nominal resolutions from <1 μm up to >100 μm for sample cross-sections <1 mm up to1 m and 100 kg in size and weight respectively);
High performance computing suite offering commercial and non-commercial image processing and analysis tools;
Data management system for entire workflow;
Core technology areas: Image reconstruction, Image processing & computer vision, Image quantification and modelling, in situ and alternative image acquisition strategies, Multi-modal correlative imaging;
Core application areas: Biomedicine, Crop & soil science, Structural & advance materials, Palaeontology and heritage;
Regular μCT training courses for internal and affiliated PhD students;
Commercial and academic collaborations for developing novel CT imaging techniques and strategies and for establishing μCT imaging in new application areas;
Established biological, medical & pre-clinical research collaborations via the Southampton Biomedical Imaging Unit and Southampton Imaging.

Micro-computed tomography (μCT)
Zeiss Xradia Versa 510 (high-resolution and phase contrast-enhanced imaging)
Custom 225kV Nikon/Metris HMX ST (different X-ray targets, robotic sample exchange)
225kV/450kV hutch: Nikon/Metris custom design (medium and high energy source, large user labyrinth, large field of view)
160kV benchtop: Nikon/Metrix CT 160 Xi (standard μCT benchtop system)
SkyScan1176 in vivo CT (in vivo small animal scanner, physiological monitoring, located at Southampton General Hospital)
In situ conditioning devices
Deben Coolstage (-20oC - +50oC)
Deben CT5000 tension/compression stage
In-house liquid nitrogen cryostat
In-house tension/compression stages (1 to 200kN ratings)
Customised device manufacture
High performance computing suite
High performance computer workstations for data visualisation and analysis
Large local data storage (~250TB) for on site data processing
Fast internal data network (fibre optic) for data processing and data backup/retrieval
Commercial and non-commercial tools for data visualisation and analysis
VGStudio Max
Simpleware (ScanIP, ScanCAD, ScanFE)
CT Pro (FBP reconstruction)
Digisens (iterative reconstruction)


Gail McConnell
+44 (0)141 548 4805

Gillian Robb (Facility Manager)
+ 44 (0)141 548 2928

Centre for Biophotonics
Strathclyde Institute for Pharmacy and Biomedical Sciences
University of Strathclyde
161 Cathedral Street
G4 0RE


  • Open to all users (academic, non-academic)
  • Internal
  • External commercial, external academic & external public
  • DIY following training or with technical help

Core Facility
Development of Optical instrumention and high-resolution optical imaging.
Wide-field epi-fluorescence microscopy, with time-lapse and fast acquisition (100fps) options. Multi-photon laser scanning microscopy with excitation wavelengths from 680-1600nm using commercial and home-built ultra-short pulsed lasers.
Coherent anti-Stokes Raman scattering (CARS) microscopy.
Wide-field and confocal laser scanning optical mesoscopy using Mesolens technology.

Future requirements
New tools for illumination and light sources

Confocal microscopy
Leica TCS SP5 with DM6000B upright microscope
Leica TCS SP5 Multi-photon/confocal microscope
Fluorescence imaging
Upright Nikon E600F epi-fluorescence microsocpe
Nikon TE300 inverted microscope with Solent Scientific environmental chamber, Sutter Scientific Lambda 12 controller
Coherent Mira-F (2x: 150 fs, 700-920nm)
Coherent Mira-D (150ps or 2ps, 700-920nm)
Fianium 2W Yb:YAG laser (300fs, 1064nm)
OPO I (~150 fs or ~2ps, 920-1180 nm)
OPO II (~300 fs, 1380-1600nm)
Many other wavelengths and supercontinuum sources available - please contact us!
Systems that *may* become part of facility in due course - availability currently upon request:
CARS microscope based on Olympus FV300 & modified Olympus IX inverted platform.
Optical trapping & fluorescence system - suitable for live cell manipulation.
Olympus FV1000 with dual-scanning system/IX inverted microscope
Image Processing
Image analysis software including Volocity, Metamorph and ImageJ


Rachel Butler 
+44 (0)1483 686428

Prof. G Stewart
+44 (0)1483 686423

Bioimaging and Flow Cytometry Facility (BIAFC)
Department of Microbial Sciences
Faculty of Health and Medical Science
University of Surrey


  • Internal 
  • External commercial & external academic 
  • DIY or assisted work

Core Facility.
Time-lapse microscopy

Confocal microscopy
Zeiss LSM510 META inverted confocal microscope (3-laser)
Nikon A1M inverted confocal microscope (4-laser)
EVOS FL widefield microscope
Flow cytometry
FACS ARIA (9-colour)
FACS Canto (6-colour)


Peter O'Toole
+44 (0)1904 328722

Jo Marrison
+44 (0)1904 328720

Imaging and Cytometry Laboratory
Technology Facility Department of Biology
University of York
YO10 5DD


  • Internal (80% on all instruments)
  • External commercial & external academic (20% on all)
  • DIY or Full service work

Core Facility.
Probe development and high resolution imaging.
Offers a range of microscopy courses.

Confocal microscopy
Zeiss LSM 880 invert with AiryScan and on stage incubation chamber
Zeiss LSM 780 META multiphoton invert with Solent Scientific environmental chamber
Zeiss LSM 710 META upright 
Zeiss LSM 510 META invert with Solent Scientific environmental chamber
Andor Revolution XD Spinning Disk with Solent Scientific environmental chamber
Wide field and Fluorescence Microscopy
Zeiss AxioScan Z1 fluorescence and brightfield slide scanner
Phase Focus inverted ptychographic system (VL20)
EM CCD imaging
PALM laser capture/microdissection
Live cell imaging chambers
Electron microscopy
FEI Tecnai 12 TEM
Jeol 6490 SEM with cryosystem
High resolution Jeol 7500F FEG SEM
GATAN CL and Cryo
Clairscope ASEM
Image analysis
Zeiss Axiovision
PE Volocity
TissueGnostics HistoQuest and TissueQuest

Flow cytometry
2 Beckman Coulter CyAn flow cytometers
BD LSR Fortessa X-20 flow cytometer
Beckman Coulter Astrios high-speed sterile cell sorter
Apogee flow system A40