Staff within the Department of Health Sciences have a strong track record of successful involvement in research trials in both the addiction and mental health fields. The majority of these trials have been conducted with some form of collaboration with York Trials Unit, a UKCRC fully registered trials unit based within the Department.
This theme focusses on developing and testing interventions that help people who already have, or are affected by addictive behaviour or mental health problems. Researchers working within this theme believe in prevention, in intervening as early as possible to avoid problems, or to make them less severe and enduring if already present. Working with trialists in York Trials Unit, researchers within the Mental Health and Addictions Research Group (MHARG) are well placed to conduct rigorous randomised controlled trials (RCTs) that evaluate intervention effects with as little bias as possible, both within the NHS and similar healthcare environments, and in other settings.
The study aims to evaluate the delivery of brief psychological support via community pharmacies to people living with long-term health conditions who will be at an increased risk of developing depression.
In this study we will conduct a large scale randomised trial of the effectiveness of screening and low intensity psychosocial interventions for older people (over 65s) with moderate to severe depression.
In this study we conducted a randomised controlled trial looking at the clinical and cost effectiveness of a “bespoke smoking cessation” intervention for people with severe mental ill health such as schizophrenia or bipolar disorder.
The SHARD Trial examined a self-help booklet for older people with subthreshold (low severity) depression. Funded by the National Institute for Health Research.
RESPECT aims to develop an evidence-supported and co-produced manualised sexual health intervention designed for people with SMI in the UK and assess the feasibility and acceptability of the intervention delivered within mental health services.
A mixed methods project with six complementary phases which aims to: i) develop an evidence based psychosocial intervention to reduce transmission risks among people who inject drugs at risk of acquiring or transmitting blood borne viruses and; ii) conduct a feasibility randomised controlled trial of the intervention.
The COBRA trial will compare the cost and the outcome of the therapies in order to find out which one of the treatments will be most useful for the treatment of depression.
The CASPER trial examined a treatment called Collaborative Care for older people with subthreshold (low severity) depression. We are currently carrying out an extended follow-up with participants from the CASPER Trial.
Funded by: National Institute for Health Research HTA.
Researchers from the Department of Health Sciences in collaboration with colleagues from the School of Psychology at the University of Birmingham aim to adapt an evidence-based family and social network intervention for substance-related problems to the youth context.
In this study we will conduct a randomised trial looking at the clinical and cost effectiveness of two self-help treatments (Guided Self-Help and Computerised CBT) compared to a waiting list control for people with OCD.
The overall aim of the ARiAS research programme is to investigate methods of improving the physical and mental health of people with alcohol and/or illicit drug problems who are identified within an acute hospital setting.
The concept of social stories was created by Carol Gray in 2000. These are simple, short stories, usually with the autistic child in the starring role, often with helpful photographs and illustrations and a theme relating to a particular social difficulty or life-skill problem.
Project page
REEACT is a randomised controlled trial which aims to compare two types of computerised cognitive behaviour therapy (CBT) packages (one free-to-use and one commercial) to see if there are any additional benefits of offering this treatment to the care that people already receive from their GP.
This study will develop a 'bespoke smoking cessation' service targeted to meet the needs of those with serious mental health problems such as schizophrenia, and will test the clinical and cost effectiveness of this approach in a randomised controlled trial.
Muslim Communities Learning About Second-hand Smoke (MCLASS) is a cluster, randomised, controlled pilot trial of 'Smoke Free Homes' delivered in Islamic religious settings (mosques hosting communal prayers, study circles for women and Qur'an classes for children) with embedded preliminary health economic and qualitative analyses.
ACTAD is a randomised control trial to determine the effectiveness of ACT for the treatment of alcohol dependence compared with standard treatment.