Short, high-voltage electrical pulses applied to a cell membrane induce temporary pores that allow drugs or DNA to pass through. We have achieved electroporation with radio frequency pulses, and have quantified the effects of pulse frequency and field strength, our eventual aim being an in-vivo applicator that has significant advantages over conventional electroporation using direct-current pulses. We have been supported by a White Rose Studentship and further funding from the White Rose Health Innovation Partnership, and are collaborating with the Department of Biology, the Leeds Teaching Hospitals and the University of Leeds.
- Martin Robinson
- Chao Chen
- Peter O’Toole (Department of Biology)
- Start: October 2004