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Policy and Methods for Health Technology Assessment of Drugs and Medical Devices

A UK-China Health and Economy Partnership Workshop

3rd-4th September 2021

UKCHEP logo

The UK-China Health and Economy Partnership is a novel knowledge transfer partnership that will promote long-term collaboration between Bournemouth University, University of York, University of Sheffield and University of Leeds in the UK and Fudan University, Shandong University and Zhejiang University in China.

The partnership aims to create long-term, sustainable collaboration in health economics, which will give UK and Chinese academics the means to work together on world-class educational and research outcomes that would otherwise not be possible working in isolation.

This partnership was originally launched in Jinan, Shandong province in November 2017 by Bournemouth University. British Council has funded an extension to the partnership for a further two years from January 2019 with sponsorship from GlaxoSmithKline.

This workshpp is one of a series of three workshops held by the UKCHEP universities, please see the Sheffield-Shandong and Leeds-Zhejiang workshops.

For further details on UKCHEP. 

Workshop summary

The York-Fudan Workshop will take place in the context of the UK-China Health and Economy Partnership (UKCHEP). This is a novel knowledge transfer partnership that will promote long-term collaboration between Bournemouth University, University of York, University of Sheffield and University of Leeds in the UK and Fudan University, Shandong University and Zhejiang University in China.

At the York-Fudan Workshop international experts will explore the experience of implementing HTA processes internationally, as well as the lessons learnt and methods used by the National Institute for Health and Care Excellence (NICE) in the UK. Presentations will be delivered by leaders in health technology assessment of drugs and medical devices. These will include experts from the multidisciplinary HTA ecosystem; namely: HTA regulators (NICE); HTA assessors (Centre for Health Economics (CHE), York Health Economics Consortium (YHEC)); commissioners (UK National Healthcare Service NHS Supply Chain); and academics (York and Fudan).

Faculty keynote speakers include:

  • A/Prof Cynthia Iglesias – University of York
  • Prof. Andrea Manca – University of York
  • Prof. Wen Chen – Fudan University
  • Prof. Yingyao Chen – Fudan University
  • A/Prof. Min Hu – Fudan University
  • Prof Mark Sculpher – University of York
  • Mr. Meindert Boysen – NICE
  • Dr. Matthew Taylor – York Health Economics Consortium
  • A/Prof. Luying Zhang – Fudan University
  • Mrs. Jo Gander – UK NHS Supply Chain

Speaker biographies

Wen Chen: Professor of Health Economics. Director at the Center for Pharmacoeconomic Evaluation and Research, Fudan University.

Professor CHEN received his M.D. degree in social medicine and health management from Shanghai Medical University in 1998 and completed research fellowship at School of Public Health, University of California at Berkeley from August of 2000 to May of 2001.

Currently he serves as the director of the Center for Pharmacoeconomic Evaluation and Research, Fudan University. He was the Dean of the School of Public Health at Fudan University from April 2013 to June 2017. He is often invited as investigator and advisor by national and municipal governments for various research programs in the field of Chinese healthcare system, national and provincial health insurance, pharmacoeconomics and pharmaceutical policy, health financing, etc.

He had more than 160 publications on international and Chinese health economics and management journals. He was awarded as the Excellent Talent in the New Century by the Chinese Ministry of Education in 2008.

Yingyao Chen: Professor of Health Services, Associate Dean of the School of Public Health, Fudan University (FUSPH).

Professor CHEN is director of the Key Lab of Health Technology Assessment (National Health Commission) at Fudan University. Director of WHO Collaborating Center for Health Technology Assessment and Management. Hereceived his Bachelor of Medicine at Shanghai Medical University in 1991, his Master of Public Health at Shanghai Medical University in 1997, and earned his Ph.D. in Management at Fudan University in 2006. He took part in a visiting scholar program at the University of California, Los Angeles, 1999-2001.

His academic interests focus on health technology assessment, health policy, health economics, and hospital management. He was a PI of several projects funded by the World Health Organization, World Bank, China Medical Board, Ministry of Health. He has published 150 papers in Chinese or in English, of which 140 in Chinese and 10 in English with first authorship and corresponding authorship. He is the editor-in-chief of Evidence-based Health Care Decision Making and Management, Health Services Evaluation and Disease Burdens of Main Birth Defects and Economic Evaluation of Their Preventive Strategies in China. He is a co-author of 14 books.

He serves as one of board of directors of Health Technology Assessment international (HTAi) (2016-2019), WHO Expert Members for Guideline on Country Pharmaceutical Pricing Policies, WHO TAG on Health Benefit Packages, vice chairman of the Public Health Economics Committee affiliated to China Health Economic Association, etc.

Kiran Trehan: Pro-Vice-Chancellor for Partnerships and Engagement, University of York.

Kiran is Pro-Vice-Chancellor for Partnerships and Engagement at the University of York and Director of the Centre for Women’s Enterprise, Leadership, Economy & Diversity.
Kiran has a national and international reputation in a senior research / impact capacity. She has extensively published a number of journal articles, policy reports, books and book chapters on leadership, enterprise development and diversity in small firms and business. She is a pioneer who promotes research, engagement and impact to facilitate widening participation.

In 2019, Kiran was elected to be the President of the Institute for Small Business and Entrepreneurship (ISBE). ISBE is the leading national body for SME research and policy learning. 

Hassan Yazdiffar: Professor of Accounting. Head of Department for Accounting, Finance and Economics.

Professor Hassan Yazdifar is the Head of Department (Accounting, Finance and Economics) at Bournemouth University (UK) and has achieved success in management, consultancy and leadership roles within industry, and academia. Professor Yazdifar has undertaken the responsibility of several research projects funded by the Chartered Institute of Management Accountants - CIMA (UK); and is currently also the Project Investigator for two British Council China and Egypt projects, and Co-Investigator for the National Institute for Health Research (NiHR) project. His experience is in both developed and developing countries and considers globalisation as an important factor in developing business performance, research and development, and developing knowledge transfer and building partnerships.

Gill Caldicott: Director of the British Council in East China.

Gill is the Director of the British Council in East China, with responsibility for leading the UK’s cultural relations and educational exchange work in the three Eastern provinces of Anhui, Jiangsu and Zhejiang, as well as Shanghai Municipality.

She holds the diplomatic rank of Consul where she manages the UK’s education and cultural relationship on behalf of the British Consulate General Shanghai.

Mark Sculpher: Professor of Health Economics at the Centre for Health Economics, University of York.

Mark is the incoming (Oct 2021) Director of the Centre for Health Economics at the University of York. For the past 20 years he’s been Team Leader of the Programme on Economic Evaluation and Health Technology Assessment. He is also Co-Director of the Policy Research Unit in Economic Evaluation of Health and Care Interventions (EEPRU).
Prof. Sculpher has worked on economic evaluations of a range of technologies including heart disease and various cancers. He has also contributed to methods in the field, in particular relating to decision analytic modelling and handling uncertainty. He has over 280 peer-reviewed publications and is a co-author of two major text books in the area: Methods for the economic evaluation of health care programmes (OUP, 2015 with Drummond, Claxton, Torrance, and Stoddart) and Decision modelling for health economic evaluation (OUP, 2006 with Briggs and Claxton). He was also a member of the Second Panel on Cost-Effectiveness in Health and Medicine.

Mark was a member of the National Institute for Health and Care Excellence (NICE) Technology Appraisal Committee (2004-8), the NICE Public Health Interventions Advisory Committee (2006-9) and the NICE Diagnostics Advisory Committee (2010-20). He chaired NICE's 2004 Task Group on methods guidance for economic evaluation and was a member of the Methods Working Party for the 2008 update of this guidance.

Meindert Boysen: Deputy Chief Executive and Director of the Centre for Health Technology Evaluation. National Institute for Health and Care Excellence (NICE).

After qualifying as a pharmacist, Meindert worked in a hospital in the Netherlands and held positions in health outcomes and sales in the pharmaceutical industry.

He completed an MSc in Health Policy Planning and Financing at the London School of Hygiene and Tropical Medicine and the London School of Economics and Political Sciences and briefly worked for the King’s Fund before starting at NICE in 2004.

Meindert was previously in the Board of Directors for the International Society for Pharmacoeconomics and Outcomes Research (ISPOR), from 2017 to 2020.

Matthew Taylor: Director of York Health Economics Consortium (YHEC).

Matthew has a Ph.D. in health outcomes research and an M.Sc. in health economics from the University of York, and has worked for YHEC since 2003. Matthew has led over one hundred economic evaluations for NICE, SMC and AWMSG industry submissions as well as health technology submissions in various international settings. Matthew also leads YHEC’s Outcomes Research team.

Dr Taylor teaches on the University’s Distance Learning course, and leads a number of health economics training courses at YHEC, including “Early Modelling: Using Models to Inform Drug and Device Development”, “Understanding and Critiquing Economic Models” and “Economic Evaluation for Oncology“.

Matthew is a former member of the National Institute for Health and Care Excellence (NICE) Public Health Advisory Committee, is an Expert Advisor to NICE and the Scientific Lead and Director of NICE’s Economic and Methodological Unit. He is also Managing Director (Europe) of the Minerva Health Economics Network, an international network of health economics agencies.

Min Hu: Associate Professor of Health Economics. Secretary-general of the Center for Pharmacoeconomic Evaluation and Research, Fudan University.

She received the PhD in Health Management from Fudan University. During 2012 to 2013 and 2017 to 2018, she conducted research at the Health Economic Research Center, University of Oxford and the Harvard T.H. Chan School of Public Health, respectively, as a visiting scientist.

Her research focuses on health care purchasing system, financial incentives on the behavior of providers and patients, health inequality and health economic evaluation. Her research has been funded, among others, by the National Natural Science Foundation of China, the National Social Science Fund of China, the Ministry of Education, the Ministry of Science and Technology of China, and the China Medical Board. She served as a core member of two internationally collaborated social experiments in Ningxia and Guizhou in China to re-align health system incentives and to reform on provider payments, which was granted by the Bill and Melinda Gates Foundation and World Bank respectively. She also served as a consultant for the World Bank for China health system reform in 2014 to 2015.

Cynthia Iglesias: Associate Professor of Health Economics and member of the Health Services and Policy Research group in the Department of Health Sciences.

Cynthia has been at the University of York since 1998, a time during which she held honorary appointments with the Hull York Medical School, the Centre for Health Economics, the Danish Center for Healthcare Improvements and the Luxembourg Institute of Health.

With a track record of more than 20 years in health economics and outcomes research, Dr Iglesias is recognised nationally and internationally for her applied and methodological programme of work on the evaluation of medical devices for Health Technology Assessment (HTA) decisions.

An independent member of the National Institute for Health and Care Excellence (NICE) Medical Technologies Advisory Committee (MTAC) for England and Wales (since 2012), she contributes to the Institute’s reimbursement and adoption decisions relating to a range of medical devices. More recently, Cynthia helped shape the Institute’s Evidence Standards Framework for Digital Health Technologies and led the health economics assessment of one of the first technologies that underwent NICE’s pilot in HTA evaluation of digital health technologies.

Luying Zhang: Associate Professor of Health Economics, School of Public Health, Fudan University.

She received her Ph.D degree in social medicine and health management from Fudan University in 2009 and worked as a visiting research fellow at School of Medicine, Stanford University from Sep of 2018 to Sep 2019. Currently she is an associate professor, master supervisor at School of Public Health, Fudan University. She is also the Vice Chairman of the Organization Management and Evaluation Committee of Shanghai Community Health Association, and the Youth Expert of Shanghai Health Development Research Center. She is a member of the Health Security Committee of the Chinese Society of Social Security, a member of the Health Insurance Committee, the Health Technology Evaluation Committee, and the Youth Committee of the Chinese Society of Health Economics.

Her main research interests lie on financing and payment system of health insurance, health policy evaluation, community health service. She completed as the principle investigator more than 20 projects supported by the NSFC, NOPSS, China Medical Board Foundation, Shanghai Social Science Fund, National Health Commission and the Shanghai Development and Reform Commission.

Jo Gander: Director of Clinical and Product Assurance at NHS Supply Chain.

Jo Joined NHS Supply Chain in April 2018 bringing over 30 years’ experience in healthcare combining clinical understanding, pharma-industry knowledge, and senior leadership within NHS organisations.

Having trained as a Registered General Nurse (RGN) in Harrogate, she then worked within Medical Devices and Pharmaceuticals organisations across a number of therapy areas and in a range of Sales/Marketing Clinical and General Manager roles.
Prior to joining NHSSC, Jo worked locally and regionally for the NHS as a Commissioning Group Director within a Care Trust Plus. She also operated as a senior leader within the NHS England National team.

Jo has a BA Hons in Business Studies as well as a Masters in Leadership, Innovation and Change. She has also achieved Chartered Marketer status at the Chartered Institute of Marketing (CIM).

Originally form Teesside, she now lives in Lincolnshire, with her husband, 2 children, 4 dogs, 2 cats and rather a lot of fish. Jo is a keen gardener and much of her spare time is taken up in her garden and walking her dogs in the woods.

Andrea Manca: Professor of Health Economics and co-lead of a Programme of Research in Stratified, Personalised and Precision Medicine.

Andrea is Professor of Health Economics in the Team for Economic Evaluation and Health Technology Assessment, part of the Centre for Health Economics. He is co-editor of the journals Value in Health and PLOS One. Andrea’s research interests focus on the application of statistical methods for the analysis of cost‑effectiveness and health outcomes data, as well as the use of evidence synthesis techniques for healthcare decision making. His work on the analysis of multinational cost-effectiveness data received the ISPOR 2008 Research Excellence Award for Methodology.

Andrea is currently a member of the NICE Technology Appraisal Committee, the National Institute of Health Research (NIHR) Programme Grants for Applied Research funding sub-panel, and the National Awareness and Early Diagnosis (NAEDI) Research Workstream scientific committee of the Cancer Research-UK.

Workshop timetable

York – Fudan UKCHEP Workshop Programme

Policy and Methods for HTA of Drugs and Medical Devices in China, 3rd - 4th September 2021

Day 1 Friday 3rd September 2021

Time

Activity

Speaker

Format

Language

01:00 BST – 08:00 CST

Delegates Registration

 

 

 

01:50 BST – 08:50 CST

Welcome and Introduction to morning sessions

Prof Chen Wen

Online

Mandarin

02:00 BST – 09:00 CST

Lecture 1. HTA development and application in decision making in China

Prof. Yingyao Chen

Online

Mandarin

03:20 BST- 10:20 CST

Tea /Coffee break

 

 

 

03:40 BST – 10:40 CST

Lecture 2. HTA application in health insurance listing

A/Prof. Min Hu

Online

Mandarin

05:00 BST - 12:00 CST

Lunch break

 

 

 

 

Opening Ceremony

 

 

 

07:00 BST – 14:00 CST

Introduction to Fudan University (FU)

Prof. Yingyao Chen

Online

English

07:10 BST – 14:10 CST

Introduction to University of York (UoY)

Prof. Kiran Trehan

Online

English

07:20 BST – 14:20 CST

Introduction to UKCHEP Project

Prof. Hassan Yazdifar

Online

English

07:25 BST – 14:25 CST

International Collaborative Initiatives

Mrs. Gill Caldicott

Online

English

07:30 BST – 14:30 CST

Lecture 3.1. HTA decision making in China: policy context and challenges

Prof. Wen Chen

Online

English

08:00 BST – 15:00 CST

Session 1: Q&A panel

This session will focus on:

Lecture 3.1. Please see above

Lecture 3.2. Approaches to HTA decision making: the international experience (pre-recorded)

Prof. Mark Sculpher

Prof. Wen Chen

Prof. Mark Sculpher

Prof. Andrea Manca

A/Prof. Cynthia Iglesias

Online

Online

Online

Online

Online

English

08:45 BST - 15:45 CST

Session 2: Q&A panel

This session will focus:

Lecture 4. HTA decision making in England: policy context and NICE experience (pre-recorded)

Mr. Meindert Boysen

Prof. Andrea Manca

A/Prof. Cynthia Iglesias

Prof. Wen Chen

 

Online

Online

Online

Online

English

09:30 BST- 16:30 CST

Tea /Coffee break

 

 

 

10:00 BST – 17:00 CST

Session 3: Q&A panel

This session will focus:

Lecture 5. Appraising the quality of clinical evidence in HTA submissions (pre-recorded)

Mr. Matthew Taylor

A/Prof. Cynthia Iglesias

Prof. Wen Chen

Prof. Andrea Manca

Online

Online

Online

Online

English

10:45 BST – 17:45 CST

Lecture 6.1. Appraising the quality of economic evidence in HTA submissions of drugs and medical devices in China

A/Prof. Min Hu

Online

English

11:15 BST – 18:15 CST

Session 4: Q&A panel

This session will focus on:

Lecture 6.1. Please see above

Lecture 6.2. NICE’s reference case to guide and appraise the quality of HTA submissions of drugs and medical devices (pre-recorded)

A/Prof. Min Hu

Prof. Wen Chen

Prof. Andrea Manca

A/Prof. Cynthia Iglesias

 

Online

Online

Online

Online

English

12:00 BST – 19:00 CST

End of Day 1

 

 

 

Day 2 - Saturday 4th September 2021

Time

Activity

Speaker

Format

Language

02:00 BST – 09:00 CST

Session 5: Roundtable discussion

This session will focus on Lectures 3.1 to 6.2

A/Prof. Luying Zhang

Online

Mandarin

03:20 BST- 10:20 CST

Tea /Coffee break

 

 

 

03:40 BST – 10:40 CST

Session 6: Roundtable discussion

This session will focus on HTA appraisal improvement learned from international experience

Prof. Wen Chen

Online

Mandarin

05:00 BST- 12:00 CST

Lunch break

 

 

 

06:30 BST- 13:30 CST

Group Exercise

Reading Time

Prof. Wen Chen

A/Prof. Min Hu

A/Prof. Luying Zhang

Online

Online

Online

English

08:00 BST – 15:00 CST

Session 7: Q&A panel

This session will focus on:

Lecture 7.  How to balance value and affordability (pre-recorded)

Mrs. Jo Gander

A/Prof. Cynthia Iglesias

Prof. Wen Chen

Prof. Andrea Manca

Online

Online

Online

Online

English

08: 45 BST - 15:45 CST

Tea /Coffee break

 

 

 

09:00 BST– 16:00 CST

Group Exercise

Discussion

This exercise will focus on a HTA submission appraisal

A/Prof. Cynthia Iglesias

Prof. Andrea Manca

Prof. Wen Chen

A/Prof. Min Hu

A/Prof. Luying Zhang

Online

Online

Online

Online

Online

Mandarin/

English*

10:30 BST - 17.30 CST

Group Exercise

Reporting back

Prof. Wen Chen

A/Prof. Min Hu

A/Prof. Luying Zhang

Prof. Andrea Manca

A/Prof. Cynthia Iglesias

Online

Online

Online

Online

Online

English

11:30 BST – 18:30 CST

Closing remarks / end of workshop

Prof. Chen Wen

Online

English

 *Simultaneous translation will be available at this session

Workshop resources

Further information to follow.

Press release

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Workshop report

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Related information

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