Sophie James
Research Fellow (Trial Coordinator)

Profile

Biography

Sophie joined the York Trials Unit in July 2017 following her previous research experience working within NHS and Pharmaceutical Clinical Trial teams. She has worked as a Trial Support officer/Trial Co-ordinator on five NIHR-funded multicentre RCTs, including three surgical RCTs.

Sophie has recently completed an NIHR Pre-Doctoral Fellowship during which she undertook preliminary research on the topic of measuring acceptability of surgical interventions.

Qualifications

• MSc Applied Health Research (University of York)
• BSc (Hons) Sport and Exercise Science (Sheffield Hallam University)

Research

Projects

• HAMLET - A multicentre, two-arm, non-blinded, pragmatic, parallel group, randomised controlled superiority trial assessing the clinical and cost effectiveness of Through Knee Amputation (TKA) compared to Above Knee Amputation (AKA) in patients requiring major lower limb amputations (MMLA), but who are unsuitable for a Below Knee Amputation (BKA).
• RESTART PD - A multicentre, two-arm, non-blinded, pragmatic, parallel group, randomised controlled superiority trial with the aim of assessing the clinical and cost effectiveness of Reality DTx®compared with traditional physiotherapy for patients with Parkinson’s Disease.
• SOFFT – A non-inferiority RCT of fracture fixation for simple olecranon fractures in adults

Previous Projects

• DISC – An RCT comparing injections of collagenase to surgical correction in the treatment of moderate Dupuytren's contracture
• PROMOTE – Placebo-controlled trial of methotrexate to treat painful knee osteoarthritis

Research group(s)

• Trials and Statistics

Publications

Full publications list

Sophie James' publications