I am interested in plant disease resistance and plant-pathogen interaction, and in novel approaches for enabling and enhancing breeding of improved crop varieties tolerant to environmental stress and disease. We use experimental and computational/mathematical tools to elucidate the gene regulatory networks underlying plant defence, and highlight key genes for conferring disease resistance. We also take a synthetic biology approach, using modelling to predict how to re-engineer plant defence networks to enhance disease resistance. A complementary project is investigating how pathogen effectors are targeting the host defence response to facilitate infection and ways to manipulate these pathogen-host interactions.
You can read more about our work and the Denbylab at denbylab.wordpress.com
As part of CNAP I work with industry collaborators to drive economic impact from our work. I am also interested in research with development impact, leading a project on improving leafy amaranth in SubSaharan Africa, and developing sustainable food systems, for example in the Greater Mekong Subregion.