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1
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The chemical principles behind methods which can be used
to detect ethanol in the body (g.l.c. and i.r. spectroscopy) (Storyline
MD1; Activity MD1.2). |
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2
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The following reactions involving aldehydes and ketones: formation
by oxidation of alcohols, oxidation to carboxylic acids, reduction to alcohols
and reaction with hydrogen. |
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3
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The mechanism of the nucleophilic addition reaction between an aldehyde
or a ketone and hydrogen cyanide. |
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4
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The meaning of the terms: drug, medicine, molecular recognition,
pharmacological activity, pharmacophore, receptor site, agonist, antagonist,
lead compound (Storyline in general). |
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5
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The structure of a pharmacologically active material in terms of its
functional components: pharmacore and groups which modify the pharmacore
(Storyline MD3). |
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6
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The action of biologically active chemicals and how this relates to
their interaction with receptor sites. |
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7
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The factors affecting the way that species interact in three dimensions:
size, shape, bond formation and orientation (Storyline MD4). |
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8
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The role of chemists in designing and making new compounds for use
as pharmaceuticals (Storyline MD3, MD4 and MD5). |
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9
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The role of computer modelling techniques in the design of medicines
(Storyline MD4). |
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10
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The identification of functional groups within a polyfunctional molecule
as a way of making predictions about its properties. |
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11
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How to devise synthetic routes for preparing organic compounds. |
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12
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The use of the following terms to classify organic reactions: hydrolysis,
oxidation, reduction, condensation and elimination. |
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13
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The classification of organic reactions according to their reaction
mechanisms: nucleophilic substitution, electrophilic addition, electrophilic
substitution, nucleophilic addition and radical. |
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14
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The use of a combination of spectroscopic techniques (m.s., i.r., n.m.r.
and u.v. and visible) to elucidate the structure of organic molecules. |
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