Jack Birch Unit for Molecular Carcinogenesis

A centre of excellence in research on the human bladder lining, the urothelium.

Welcome from the Director

Professor Jenny Southgate
Director of the Jack Birch Unit for Molecular Carcinogenesis

Welcome to the website of the Jack Birch Unit for Molecular Carcinogenesis. The Jack Birch Unit was opened in 1992, funded by the generosity of the late Jack Birch, OBE and York Against Cancer.

Research in the Jack Birch Unit concentrates on epithelial tissues, which give rise to more than 80% of all adult human cancers. Our main focus is on bladder cancer which is studied relatively little despite being the 5th most common adult cancer. Bladder cancers develop from the urothelium, the specialised lining of the bladder wall.

Related websites

Histotech- Specialist histology service
Providing high level consultancy
& contract research

Kystis - Our Human Bladder Tissue Model
A biologically relevant model in a 
commercially relevant format

PhD studentships

Self-funded Studentships

  • Homeostatic mechanisms in human urothelium: balancing of tissue regeneration and differentiation with implications for regenerative medicine and cancer

Fully-funded Studentships


 News and Events


New effects of ketamine abuse uncovered

Southgate x70

‌Research points to new therapies for bladder cancer

11 July 2014, A University of York scientist has played a key role in research that could help to improve the treatment of muscle-invasive bladder cancer, one of the most common cancers, particularly among men.

play video ELF3 paper Jack Birch Unit

PhD student Jenny Hinley describes a recent study from the Jack Birch Unit which has been published in Developmental Biology

EAU video  thumbnail23 April 2010, JBU scientists win $300,000 bladder research award



From left to right: Lead author Alex Turner, Professor Francesco Montorsi, and Koos AdmiraalYork Scientists win research accolade


Katamine news from BBC websiteKetamine news on BBC website