Accessibility statement

Lesley Sinclair
Research Fellow (Trial Manager)



Lesley joined YTU in January 2022 from the University of Edinburgh where she was a Research Fellow/Trial Manager with the Usher Institute. Lesley has worked in both NHS and University settings and has more than 20 years’ practical experience in the design, management and delivery of health services research involving a range of patient groups. From 2011 to 2021 Lesley’s work focussed on taking forward a portfolio of projects relating to smoking cessation. Lesley has particular expertise in clinical trial and project management and has an MSc in Clinical Trials from the London School of Hygiene and Tropical Medicine.


  • BSc Mathematics for Business Analysis
  • MSc Clinical Trials




Lesley has an interest in the following:

  • Randomised controlled trials
  • Feasibility studies
  • Complex interventions
  • Smoking cessation


  • BART II – RCT of cognitive behavioural therapy in adults at high risk of developing bipolar disorder.
  • EXTEND – RCT of EXTENDed antibiotics to improve outcomes in patients with complicated intra-abdominal infection

  • OPAL2 – Effectiveness and cost-effectiveness of occupational support for people undergoing planned surgery for lower limb joint replacement.

Research group(s)

  • Trials and Statistics


Randomised controlled trials for smoking cessation



Full publications list

External activities


  • UK Trial Managers' Network

Contact details

Lesley Sinclair
Research Fellow (Trial Manager)

Tel: 01904 32(4158)