Health Sciences
Supporting people in Yorkshire who smoke to Quit: The YorQuit study
Background/Aims
Lung cancer rates are higher in Yorkshire than in the rest of the UK, but deaths from lung cancer can be prevented by screening, and a national screening programme has been recommended. Evidence shows that adding stop-smoking support to screening can increase the number of lives saved. Local stop smoking services offer support in different ways and we want to find out the best way to help people who want to stop or cut down their smoking. This study will compare three different ways of providing stop smoking support to people contacted by the Targeted Lung Health Check programme. This will allow us to test the acceptability, accessibility, effectiveness, and cost effectiveness of each of the methods of providing stop smoking support. The study starts in 2024 and will run for around 4 years.
Study design
A pragmatic, parallel-group, three-arm, randomised controlled trial with embedded economic and process evaluations.
Who will take part?
Participants will be attendees of lung health check programmes in Hull, Bradford, Leeds, and Manchester who are current smokers and interested in quitting or changing their smoking habits. Around 2000 people will join the study over a 2-year period.
What does the study involve?
Consenting participants will be randomly placed into one of three groups: 1) to receive support from local stop-smoking services, plus the offer of a free subscription to the Smoke Free app; 2) to receive telephone support from a stop smoking advisor who works in the YorQuit study team; or 3) to receive the same support as people in group2, plus the opportunity to receive shopping vouchers for giving up smoking.
Everyone who joins the study will be asked to complete questionnaires at 4 weeks, 3 months and 12 months after joining the study. These questionnaires will ask about smoking behaviour, current health and social care usage, and stop smoking aids used. Abstinence from smoking will be confirmed by a carbon monoxide (CO) breath test.
We will also ask what those receiving and delivering the stop smoking support think about it, and their opinion on the effectiveness of the support. Data from the questionnaires and interviews will help us to find out if there is a difference between the groups in smoking status, and if there is a need for additional support. We will also find out if the cost of care differs between the groups, to determine whether one is better value for money for the NHS.
The end of the study will be when the 12-month questionnaire is completed and, if required, CO reading collected for the last participant.
What is the primary outcome measure?
7-day point prevalent CO validated smoking cessation at three months after commencement of smoking cessation intervention.
Ethical approval
This study has been reviewed and given a favourable opinion by the East Midlands – Leicester South Research Ethics Committee.
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Funding
| Funders(s) | Yorkshire Cancer Research (Ref: RA/2023/R2/113) |
|---|---|
| Start Date | April 2024 |
| End Date | June 2028 |
Members
YTU Team
- Lesley Sinclair – Trial Manager
- Rebekah Howell – Trial Co-ordinator
- Qi Wu – Research Fellow/Health Economist
- Alex Mitchell - Statistician
- Justin Fenty – Statistician
- Catherine Hewitt – Director YTU
- Jude Watson – Deputy Director YTU
External Team
- Rachael Murray (Co-CI) – Professor of Population Health, University of Nottingham
- Matthew Callister (Co-CI) - Consultant in Respiratory Medicine, University of Leeds and Leeds Teaching Hospitals NHS Trust
- Sanjay Agrawal – Consultant Respiratory Physician, University Hospitals of Leicester
- David Baldwin - Honorary Professor of Medicine and Consultant Respiratory Physician, University of Nottingham
- Kate Brain - Professor of Health Psychology, University of Cardiff
- Leanne Cheyne - Consultant Respiratory Physician, Bradford Teaching Hospitals NHS Trust
- Phil Crosby, Professor of Respiratory Medicine, University of Manchester
- Matthew Evison – Consultant Chest Physician, Manchester University NHS Foundation Trust
- Elizabeth Orton, Professor of Public Health, University of Nottingham
- Andrew Sloss, PPI Representative
- Pamela Smith, Research Associate, University of Cardiff
- Kanwal Tariq - Consultant Respiratory Physician, Hull University Teaching Hospitals NHS Trust
- Rebecca Thorley, Project Manager, University of Nottingham
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