Isabella Dutton
Research Fellow (Trial Coordinator)

Profile

Biography

Isabella joined York Trials Unit in 2026 as a Research Fellow (Trial Coordinator). She has a background in immunology and previously worked in the immunodiagnostics industry, contributing to clinical trials such as iStopMM.

Qualifications

• BSc (Hons) Biochemistry (University of Worcester)
• MSc Clinical Trials (University of Edinburgh) (In-progress to be completed in June 2026)

Research

Projects

• FARSTER-Care - An RCT investigating whether, following cardiac surgery with full median sternotomy, an accelerated cardiac rehabilitation pathway will lead to improved patient outcomes and is cost effective compared to the usual timing of cardiac rehabilitation.
• HAMLET - A multicentre, two-arm, non-blinded, pragmatic, parallel group, randomised controlled superiority trial assessing the clinical and cost effectiveness of Through Knee Amputation (TKA) compared to Above Knee Amputation (AKA) in patients requiring major lower limb amputations (MMLA), but who are unsuitable for a Below Knee Amputation (BKA).

Research group(s)

• Trials and Statistics

Supervision

Isabella has a background in immunology, focussing on Multiple Myeloma diagnosis, monitoring and therapeutic treatments.

Publications

Selected publications

• Iliev, V. et al. (2025). ‘A-142 Impact of Demographic and Clinical Factors on Serum Free Light Chain Measurements in a Multi-Ethnic US Population’. Clinical Chemistry, 71(Suppl.1), hvaf086-138. Doi: 10.1093/clinchem/hvaf086.138
• Iliev, V. et al. (2025) ‘Biological variation of soluble B-cell maturation antigen in healthy donors’, Clinical Chemistry, 71(Suppl. 1), hvaf086-137. Doi: 10.1093/clinchem/hvaf086.137
• Spalkova, E. et al. (2025) ‘Establishing biological variation of immunological and inflammatory biomarkers in healthy individuals: a longitudinal study’, Journal of Immunological Methods, 544, 113947. Doi: 10.1016/j.jim.2025.113947

Full publications list

• Isabella Dutton's publications