Accessibility statement


PROSPERO, our international prospective register of systematic reviews now holds over 10,000 published records.

Read some of the testimonials and feedback we have received about PROSPERO

Professor Dame Sally C. Davies FRS FMedsci, Chief Medical Officer and Chief Scientific Adviser, Department of Health

"Reaching over 10,000 registrations on PROSPERO is a great achievement. Through the National Institute for Health Research we are proud to be leading the world on transparency and making sure the best quality evidence is available to avoid duplicate reviews.

By promoting transparency, NIHR has already been able to avoid commissioning duplicate reviews."

MB, Aberdeen

"It is a really good idea and being free of charge is very helpful."

Amanda Hodgson Manager, Information Services, CADTH

"The PROSPERO database is an important and valued resource for CADTH. A PROSPERO search is a routine step in the CADTH scoping search process. Before CADTH initiates a new project, our Information Services team searches the PROSPERO database to determine if work is already being done, or has been completed, on a topic. Access to PROSPERO has helped CADTH avoid duplication and allowed us to focus our resources on topics where no research currently exists. It also raises our awareness on current projects undertaken by other organizations.  We’re very grateful to have access to PROSPERO and look forward to future enhancements to the database."

Laura Gougeon

"Terrific! Thank you very much for registering and for the quick turnaround."


"The librarians at MCPHS University would like to promote PROSPERO to our users…to encourage our users to register their protocols.  We would also suggest people use it to avoid duplication and to search for prospective collaborators."

Tara Schuller

The PROSPERO database is a valuable international resource for identifying potential collaborators conducting systematic reviews in similar subject areas. It provides information not only on prospective systematic reviews, but also provides updates on the status of the review - if it is underway or completed, and where the final publication can be found.  It is the only freely accessible database of its kind.  Thanks for the great work in offering and maintaining PROSPERO.



Musaiwale Kamfose

"I have had the opportunity of using PROSPERO and have to say it was so helpful in doing my systematic review. The information available is clear and easy to understand and would always use it when doing systematic review."

Pietro Ravani

"Thanks for the superb support to systematic reviews; I consider PROSPERO a great resource and handy tool for reviewers…"

Professor Lesley Stewart, Director of CRD

"CRD is proud to have led on the development and implementation of this unique register. We have been delighted by the enthusiastic response from the international research community. We also appreciate the support of many major publishers and journal editors in requesting registration details for systematic reviews submitted for publication. Reaching 10,000 registrations in less than five years with submissions from over 92 countries is a great achievement.

Having reached this important milestone, we are excited to be working with an international collaboration on the inclusion of protocols of systematic reviews of pre-clinical studies as part of the drive to reduce waste and promote high standards in health research." 


"For me Prospero has been like a guide, a mentor. As I planned my first meta-analysis, I had no clue how to organize things. But just by going through your submission form, I now have a perfect sense and direction. I hope this submission will be first of many more to come."

Paul Wilson, Deputy Editor in Chief, Implementation Science

"PROSPERO increases transparency and acts as a guard against the selective reporting of systematic review findings. It is an invaluable resource for Editors and peer reviewers as it makes it easy to check whether a review submitted for publication differs from what was planned at the outset."


"Have been very impressed by my experience of PROSPERO – easy to use and excellent communication from your team."

Mike Clarke, Chair of Research Methodology, Queen's University Belfast

"Every year, healthcare researchers produce an overwhelming amount of evidence. This can be extremely wasteful if the research is not planned or presented in the light of what is already known. Systematic reviews help to reduce this waste by bringing relevant research studies together and these reviews themselves need to be done in ways that are transparent and avoid unnecessary duplication. PROSPERO is a unique, much-needed resource, allowing reviewers to share their plans, in advance, with other researchers, practitioners and the public."

Dr Emily Sena, CAMARADES Convener

"The PROSPERO register of systematic review protocols is transforming the validity of systematic reviews, by ensuring that study identification and analyses truly is determined in advance. We very much look forward to the launch of a related system, hosted by PROSPERO, for systematic reviews of animal studies."

Dr Bryonnie Scott

"The registration system was easy to use, even for someone like myself who can find electronic interfaces difficult to get to grips. The PROSPERO process helped us develop a really clear understanding of the areas of our systematic review protocol which needed greater focus, and so improved the quality of our work. We know that it also prevented unnecessary duplication, as another team re-directed their review efforts after finding our protocol on the site." 

Dr Robert Phillips, Ass Ed Arch Dis Child (BMJ Group), Scientific Reports (Nature Group) and Ac Ed PLoS ONE (BMC group)

"It's clear to me that when I receive a systematic review for consideration in an Associate Editor role, those groups who have undertaken PROSPERO registration of their protocol are more likely to have conducted a methodologically sound review. It's not a hallmark guarantee, but it's uncommon to sink a PROSPERO registered review because of quality problems prior to seeking peer review."