Posted on 20 November 2015
On November 17th 2015 the Department of Clinical Medicine at Aarhus University, supported by Denmark’s 3R-Center, was host to a symposium on systematic reviews and meta-analysis of animal studies. Scientific groups providing lectures included SYRCLE (SYstematic Review Centre for Laboratory animal Experimentation) and CAMARADES (Collaborative Approach to Meta-Analysis and Review of Animal Data from Experimental Studies) with funding provided by the National Centre for Replacement, Refinement and Reduction of Animals in Research (NC3Rs). The presentations collectively demonstrated the value of systematic reviews and their potential for reducing waste in research, the key aim of NC3Rs. Alison Booth of the University of York Centre for Reviews and Dissemination (CRD) was invited to present at the event and she gave a lecture on the CRD PROSPERO database and the benefits of protocol registration.
PROSPERO is a major global research initiative led by CRD and funded by the National Institute for Health Research. Launched in February 2011, PROSPERO is the only open access prospective register of systematic reviews. Registration is web-based, open to all researchers planning to conduct a systematic review, free to register and free to search.
The scope for inclusion in PROSPERO initially focused on reviews of interventions, but now covers protocol details for systematic reviews relevant to health and social care, welfare, public health, education, crime, justice, and international development, where there is a health related outcome. Alison’s presentation was very well received and generated a lot of discussion between those attending and working in animal science. Collaborative work is well underway to facilitate the inclusion of reviews of preclinical scientific research in PROSPERO.