Accessibility statement

The research work packages

The programme of research in the TB and Tobacco Project consists of six major themes, each of which is linked to a set of research objectives and a distinct (but inter-related) work package (WP).

Work package 1: Development and feasibility

The objectives of WP1 are as follows:

  • Adapt the delivery of the tobacco cessation strategies to the local context
  • Identify resources and competencies for health professionals required to deliver the strategies
  • Identify organisational capacity required to deliver.

Work package 2: Effect evaluation

The objectives of WP2 are as follows:

  • Assess the effect of cytisine with behavioural support vs. behavioural support alone on smoking cessation and TB outcomes (A multi-centre, two-arm, double-blind, placebo-controlled, individually randomised controlled trial)
  • Assess any differences in the effectiveness across various sub-groups
  • Translate and validate MPSS (Mood and Physical Symptoms Scale) and SUTS (Strength of Urges to Smoke)
  • Assess adverse effects.

Work package 3: Economic evaluation

The objective of WP3 is as follows:

  • Assess cost-effectiveness of cytisine with behavioural support on smoking cessation and TB outcomes.

Work package 4: Process evaluation

The objective of WP4 is as follows:

  • Assess all relevant components of the design and delivery of the smoking cessation programme.

Work package 5: Context evaluation

The objectives of WP5 are as follows:

  • Identify contextual factors that influence the delivery of tobacco cessation strategies
  • Measure which of the contextual factors identified above predict the effect of tobacco cessation strategies
  • Assess whether contextual factors identified above and found influential (above), change over time.

Work package 6: Scale-up and sustainability

The objectives of WP6 are as follows:

  • Further refine tobacco cessation strategies
  • Predict the likely costs and effects of scaling-up tobacco cessation strategies
  • Assess the extent to which tobacco cessation strategies are sustained in the medium-term
  • Identify the likely obstacles and opportunities for scaling-up tobacco cessation strategies.

Work package 7: Management and coordination

A further work package (WP7) is concerned with management and coordination of the project.