Image analysis using advanced imaging software: copyright John Houlihan
Advanced imaging microscope system equipped with 2-photon capabilities for live cell imaging
Gel electrophoresis - loading agarose gel: Copyright John Houlihan
Exterior of new building housing state-of-the-art Wolfson Laboratories
Vasculature visualized by FITC-dextran angiography of L.donovani-infected spleen (mag x12): copyright Jane Dalton
3D imaging over time of HT1080 fibrosarcoma cells expressing GFP (green) migrating through a collagen gel
Transmission Electron Micrograph of HT0180 fibrosarcoma cell embedded in a collagen gel
Leishmania donovani specific cytotoxic T cells (green) hunt for parasites within a hepatic granuloma (red)
Hepatic macrophages (red+green) forming a granuloma as a result of infection with Leishmania donovani (white)
Capillary bed in the mouse small intestine, supplying circulation to individual villi (green autofluorescence), with arterial and venous supply from the larger vessels. Blood vessel walls have been labelled red with /Lycopersicon esculentum/ (tomato) lectin-Texas Red to permit their visualisation
Day 56 mature schistosome egg in vessel
Day 98 peyers patch granuloma resulting from schistosome infection
Inflammatory granulomas around schistosome eggs in small intestine
The CII taking part in the 2011 York Science Trail aimed at 14-16 year old students from schools across the region
The CII at the York Festival of Science Discovery Event at the National Railway Museum March 2011
Leishmania major parasites (expressing red and green fluorescent markers)
3D reconstruction of E. coli microcolonies growing on a surface. Two strains of bacteria are present one expressing GFP (green) and one tdTomato (red).
3D reconstruction of an E. coli biofilm composed of two strains, one expressing GFP (green) and one tdTomato (red). A void in the biofilm can be seen in the central area of the image, part of many channels that run through the structure.
Trypanosoma brucei bloodstream form parasites stained with anti-alpha tubulin and DAPI
Scanning electron micrograph of Trypanosoma brucei bloodstream form parasite
Transmission electron micrograph of Trypanosoma brucei bloodstream form parasite following tetracycline-inducible RNA interference of the small GTPase ARF1 (24 hours post-induction). FL, flagellum. FP, flagellar pocket.