We prepare inorganic complexes by traditional synthetic methods as well as using novel photochemical routes. In addition; we design, develop and implement nuclear magnetic resonance (NMR) methods for the study of chemical processes including those that employ in situ photolysis whilst recoding NMR data. Our work therefore involves the study of catalysis and the synthesis of novel inorganic complexes which often include ligands that are enriched in NMR active nuclei such as 13C and 15N.
We also work on hyperpolarisation, a method that increases the sensitivity of NMR and magnetic resonance imaging (MRI) by many orders of magnitude. By hyperpolarising reaction intermediates and metabolites, we seek to facilitate their detection by NMR and MRI. We have used this approach for many years, and our studies culminated in the establishment of the York Centre for Hyperpolarisation in Magnetic Resonance. This has resulted in our research interests expanding into biochemistry and the diagnosis of disease.