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Network meta-analysis & models for inconsistency

Thursday 15 January 2015, 12.30PM to 1.30pm

Speaker(s): Dr Ian White, MRC Biostatistics Unit

Abstract: Network meta-analysis (multiple treatments meta-analysis) is an increasingly popular way to combine a body of evidence and try to identify the best intervention. I will give an introduction to statistical models for network meta-analysis and how they are fitted and interpreted. A major assumption of these models is that different sources of evidence are mutually consistent. We can test this assumption using models that allow for inconsistency. I will describe the “design-by-treatment interaction model” and compare it with other inconsistency models in the literature. I will also discuss what can be done when inconsistency is detected.

Location: ARRC Auditorium A/RC/014

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