Thursday 8 February 2018, 2.00PM to 3.15pm
Speaker(s): Nicholas Latimer, ScHARR, University of Sheffield
Abstract: Estimates of the overall survival benefit of new cancer treatments are often confounded by treatment switching in randomised controlled trials (RCTs). For Health Technology Assessment (HTA) estimates of the unconfounded overall survival benefit associated with new treatments are needed. Several switching adjustment methods have been advocated in the literature, some of which have been used in HTA, but all make strong assumptions that are not possible to test perfectly. In addition, each of these methods can be applied in a multitude of ways and seemingly innocuous choices around how a particular method is applied can importantly affect the results they produce. In this talk I will introduce the adjustment methods and will focus on key application decisions to watch out for when undertaking or assessing adjustment analyses.
Location: ARRC Auditorium A/RC/014
Who to contact
For more information on these seminars, contact:
Adrian Villasenor
Adrian Villasenor-Lopez
Dacheng Huo
Dacheng Huo
If you are not a member of University of York staff and are interested in attending the seminar, please contact Adrian Villasenor-Lopez or Dacheng Huo so that we can ensure we have sufficient space
CHE Seminar Programme
- Monday 21 January
Professor Rachel Baker, Yunus Centre for Social Business and Health- Thursday 7 February
Professor Philip Clarke, The Universities of Melbourne and Oxford- Thursday 7 March
Professor Sonia Bhalhotra, University of Essex- Thursday 4 April
Eugenio Zucchelli, Lancaster University- Monday 13 May
Davide Rasella, Fiocruz Brazil- Thursday 4 July
Stephanie von Hinke Kessler Scholder, Bristol University- Thursday 5 September
Jose-Luis Fernandez, LSE- Thursday 3 October
Soren Rud Kristensen, Imperial- Thursday 7 November
Linda Davies, Manchester University- Wednesday 5 December
Mandy Ryan, HERU, University of Aberdeen