Dr Paul Huxley
Postdoctoral Research Associate - Mathematical Modelling

Profile

Research

Overview

• Mathematical and statistical modelling of mosquito population and transmission dynamics.
• Environmental drivers of vector fitness and disease risk.
• Development and curation of trait databases for model parameterisation.
• Bayesian inference and uncertainty quantification.
• Integration of ecological, demographic, and intervention processes into policy-relevant simulation models.

Projects

Mathematical and statistical modelling of gene drive systems.

Research group(s)

Professor Luke Alphey Group.

Publications

Selected publications

Huxley PJ, Brown JJ, St. Laurent B, Johnson B, Cheung OY, Asamoah A, Hollingsworth BD, Bump ER,
Wimberly MC, Pascual M, Johnson LR — Beyond temperature: Relative humidity systematically shifts the
temperature dependence of population growth in a malaria vector.
https://doi.org/10.1101/2025.05.30.656372. bioRxiv. Under review. (2025)

Da Re D, Andreo V, San Miguel T, Blaha M, Rosà R, Rizzoli A, Harrison J, Sorek S, Johnson LR, Huxley PJ —
AedesTraits: A global database of temperature–dependent trait responses in Aedes mosquitoes.
https://ecoevorxiv.org/repository/view/8919/. Accepted. (2025)

Sorek S, Smith JW, Huxley PJ, Johnson LR — bayesTPC: Bayesian inference for Thermal Performance
Curves in R. https://doi.org/10.1111/2041-210X.70004. Methods Ecol Evol. (2025)

Huxley PJ, Johnson LR, Cator LJ, Pawar S — Discrete- versus continuous-time representations of thermal
fitness in organisms with complex life histories. https://doi.org/10.1101/2024.08.09.607340. Accepted.
(2025)

Ryan SJ, Huxley PJ, Lippi CA, Pawar S, Cator L, Rund SSC, Johnson LR — MIReVTD, a Minimum
Information Standard for Reporting Vector Trait Data. https://doi.org/10.1101/2025.01.27.634769. Under
review. (2025)

Pawar S, Huxley PJ (joint lead author), Smallwood TR, Nesbit ML, Chan AH, Shocket MS, Johnson LR,
Kontopoulos DG, Cator LJ — Variation in temperature of peak trait performance constrains adaptation of
arthropod populations to climatic warming. https://doi.org/10.1038/s41559-023-02301-8. Nature Ecol
Evol. 2024

Shocket MS, Caldwell JM, Huxley PJ, Lippi CA, Windram FA, Keyel AC — Modelling the effects of climate
and climate change on transmission of vector-borne disease.
https://doi.org/10.3920/9789004688650_012. In Planetary Health Approaches to Understand and
Control Vector-Borne Diseases. Wageningen Academic, 2023.

Huxley PJ, Murray KA, Pawar S, Cator LJ — Competition and resource depletion shape the thermal
response of population fitness in Aedes aegypti. https://www.nature.com/articles/s42003-022-03030-7.
Commun Biol. 2022

Huxley PJ, Murray KA, Pawar S, Cator LJ — The effect of resource limitation on the temperature
dependence of mosquito population fitness. https://doi.org/10.1098/rspb.2020.3217. Proc. R. Soc. B.
2021

Shah HA, Huxley P, Elmes J, Murray KA — Agricultural land-uses consistently exacerbate infectious
disease risks in Southeast Asia. https://doi.org/10.1038/s41467-019-12333-z. Nat Commun. 2019