Welcome

Dr. Paul A. Clarke

E-mail: paul.clarke@york.ac.uk

Dr. Paul Clarke began his career at the University of Bath where he obtained his B.Sc(Hons) in 1993. He remained at Bath to study the utility and mechanism of intramolecular dioxirane epoxidation reactions under the supervision of Dr. A. Armstrong. In 1996, he obtained his Ph.D and moved to Florida State University where he spent two years working with Prof. R. A. Holton on the synthesis and functionalisation of taxane ring systems. In 1999, he returned to the UK to work on a carbenoid insertion approach to peptide synthesis with Prof. C. J. Moody at the University of Exeter. In September 1999, he was appointed as a lecturer in Organic Chemistry at the University of Nottingham. In January 2006, he moved to the University of York as a Senior Lecturer and then later was promoted to Reader. In 2009 he was admitted as a Fellow of the Royal Society of Chemistry. Paul was a visiting academic at Universidad Complutense, Madrid, Spain in 2010 and 2011 and at the Research School of Chemistry at the Australian National University, Canberra in 2018. From 2013-2017 he was on the editorial board of the international Open Access Journal Advances in Chemistry and from Jan 2013 to Dec 2015 he was Chair of the Department of Chemistry's Graduate School. Paul is currently on the editorial board of the journal Life and has acted as a chemistry consultant for Vertex Pharmaceuticals. From 2010, Paul has been a member of the Yorkshire and Humber SCI Regional Committee, and is now its Chair. When not involved in chemistry-based activities he can usually be found enjoying a beer or a G&T!

Past Group Members

Rebecca Davie (2000-2003)
Towards the synthesis of the ABC-rings of FR182877.

Matthew Grist (2000-2003)
Synthesis of a DEF-ring core of hexacyclinic acid and FR182877.

Blaithin Boland (2002-2003)
Development of Methodology Towards the Synthesis of Reduced Heterocycles.

Krzysztof Ambroziak (2003-2004)
Asymmetric catalysis using metal salen complexes.

William Martin (2001-2004)
New Strategies for the Synthesis of Tetrahydropyrans.

Martin Smith (2001-2004)
Desymmetrisation of 1,n-diols using lanthanide (III) salts.

Pablo Suarez (2004-2005)
The Asymmetric Maitland-Japp Reaction.

Richard Black (2002-2005)
Transannulation Reactions in Natural Product Synthesis.

Dr. Nigel Bainbridge (2005-2006)
Strategies for the Synthesis of the FR182877 Ring Systems.

Dr. Matthew Vale (2004-2006)
The Absolute Asymmetric Preparation of Amino acids and Carbohydrates.

Andrew Cridland (2003-2006)
Synthesis of the ABC-Rings of Hexacyclinic acid.

Dr. Wencke Steinle (2005-2007)
Synthesis of the C33-C46 Tail of the Phorboxazoles.

Dr. Andrey Zaytzev (2006-2007)
Pot, Atom and Step Economic Synthesis of Highly functionalised Piperidines

Mei-Hsuan Tsai (Maggie) (2006-2007)
Towards the Synthesis of Prelactone B

Gabriele Rolla (2004-2007)
Towards the Synthesis of the ABC-rings of Hexacyclinic acid

Soraia Santos (2004-2007)
Pot, Atom and Step Economic Synthesis of Highly Functionalised THPs: Synthesis of the bis-Pyran Unit of Phorboxazole B

Jason Hargreaves (2005-2009)
Strategies for the synthesis of the C20-C32 Core of the Phorboxazoles

Dr. Elin Abraham (2008-2009)
Synthesis of the Polyene Tail of the Phorboxazoles

Dr. Dan Woollaston (2008-2010)
Strategies for the synthesis of the C20-C32 Core of the Phorboxazoles and the Pinguisanes

Andrew Reeder (2007-2010)
Towards the synthesis of the Pinguisane-type sesquiterpenoids

Mudassar Iqbal (2007-2010)
Studies on the total synthesis of Hexacyclinic acid

Nimesh Mistry (2007-2011)
Synthesis of the C1-C19 bis-pyran unit of phorboxazole B and synthesis of sialic acid analogues

Joby Winn (2008-2011)
Transannulation reactions in the synthesis of sesquiterpene natural products

Laurence Burroughs (2008-2011)
Prebiotic genesis of carbohydrates

Helen Summers (2010-2011)
Synthetic Studies on Diospongin A

Bun Yeung (2010-2012)
Synthesis of pyran and related natural products

Philip Sellars (2008-2012)
Stereoselective synthesis tetrahydropyrans and dihydropyrans

Ugur Kaya (2013)
Investigating the stereodivergent oxy-Michael reaction

Kristaps Ermanis (2010-2014)
Stereodivergent oxy-Michael Reactions and the Synthesis of the C20-C32 Core of the Phorboxazoles

Nicolas Bia (2015)
Prebiotic Genesis of Carbohydrates

Marie Fabre (2016)
Synthesis of 3D-Piperidines

Josh Smith, (2012-2016)
Studies Towards the Total Synthesis of Retronecine and Anthracimycin

Nadiah Mad Nasir (2012-2016)
Development of New Methods for the Synthesis of Dihydropyrans and Tetrahydropyrans

Zhao Yuxiong (2015-2016)
Stereodivergent Synthesis of the C1-C19 Fragment of the Phorboxazoles

Andrew Steer (2013-2017)
Prebiotic Synthesis of 2-Deoxy-D-Ribose

Yin-Ting Hsiao (2013-2017)
Application of a Stereodivergent Oxy-Michael Reaction to Natural Product Synthesis.

Dr. Ian George (2015-2017)
Total Sythesis of Anthracimycin

Sam Griggs (2014-2018)
Synthesis of 2-Spiropiperidines

Haonan Yuan (2015-2018)
A Biomimetic Synthesis of Anthracimycin

Nannapaneni Sai Pavan Chakravarthy (2017-2018)
Asymmetric Synthesis of Tetrahydropyrans

Bastien Duchadeau (2018)
Asymmetric Synthesis of Tetrahydropyrans via Kinetic Resolution

Nikolaos Vagkidis (2018)
Asymmetric Organocatalysis with Aminonitriles

Giacomo Lodovici (2015-2018)
Synthesis of the Decalin Core of Anthracimycin