Cancer cell & molecular biology - BIO00068H
Module summary
The cellular and molecular abnormalities of cancer will be analyzed and the latest theraputic advances.
Module will run
| Occurrence | Teaching period |
|---|---|
| A | Autumn Term 2022-23 to Summer Term 2022-23 |
Module aims
This module will review current knowledge, underpinning principles and recurrent themes in the molecular and cellular biology of cancer. We will discuss the key features of cancer biology, such as deregulated cell cycle progression, growth, invasion and metastasis. A major area of focus will be the mechanisms of action of oncogenes (e.g. Myc) and tumour suppressors (e.g. p53). The module will include the importance of cancer stem cells and the tumour microenvironment, the spread of cancer and therapeutic advances. It will present general principles and key molecules, describing how they achieve their functions. All stages will be illustrated with examples that are of particular interest and importance. A key feature will be molecular strategies for cancer therapy. Experiments from cancer research papers will be examined in detail to provide training in comprehension, criticism and data interpretation.
Module learning outcomes
1. Interpret data from experiments investigating cancer.
2. Discuss the molecular and cellular basis of cancer.
3. Evaluate therapeutic approaches in current use and development in cancer.
Indicative assessment
| Task | % of module mark |
|---|---|
| Online Exam - 24 hrs (Centrally scheduled) | 100 |
Special assessment rules
None
Indicative reassessment
| Task | % of module mark |
|---|---|
| Online Exam - 24 hrs (Centrally scheduled) | 100 |
Module feedback
Cohort-level feedback will be provided on performance in closed exams and made available via the VLE. Histograms of module marks will be posted on the notice boards outside the Biology Student Services office. Individual marks will be made available to you and your supervisor via e:vision. Exam scripts will be made available at the end of either the Spring or Summer terms. You should take the opportunity to discuss your marks and feedback with your supervisor.
During the teaching of the module you will receive feedback that may be at a whole class or individual level. Forms of feedback may include: model answers and discussion of workshop questions, summaries of performance in practicals, VLE-based quizzes, individual spoken comments during workshops, individual written comments on formative work.
Indicative reading
These are available through the VLE module site.