TARGeTED Antimicrobial Resistance (AMR) Project 

Welcome to TARGeTED: Tackling Antimicrobial Resistance with Goal-orientated Thinking across the EPS (Engineering and Physical Sciences) Disciplines

Anna Dumitriu is our new AMR Artist in Residence

About us

About us

The University of York TARGeTED Community is developing new interdisciplinary collaborations and innovative approaches to tackle the AMR challenge. Inspiring goal-orientated research we are bringing together staff from across departments to develop:

  • Novel tools for understanding and controlling bacterial behaviour
  • Novel biosensors and diagnostics

Our objectives

  • A clear and shared understanding of the elements of the AMR Challenge that University of York is best placed to address
  • A culture of engagement with ‘goal-orientated’ thinking between Engineering, Physical, Biological and Social Scientists
  • Active and developing collaborations to enable knowledge exchange
  • Proof-of-principle research to test the validity of our proposed solutions to AMR problems

Governance structure

Chair

Professor Maggie Smith (Biology)

Steering Group

Professor Martin Bees (Mathematics), Dr Steve Johnson (Electronics), Professor Thomas Krauss (Physics), Professor Susan Stepney (Computer Science), Professor Tony Wilkinson (Chemistry), Emma Brown (Research & Enterprise Office), Dr Rachel Curwen (Research & Enterprise Office)


How we are funded

We successfully applied for funds from EPSRC's Network for Antimicrobial Action 'Bridging the Gap' call (EP/M027538/1). Read our EPSRC Case for Support‌ for more information (University of York only).


Events

Forthcoming events

Coming soon

  • Biofilms workshop

Events archive

View presentations from the 'Industry Communications Training' Seminar: Wednesday 16 November 2016

Tracking the transmission of Clostridium difficile Seminar: Friday 21 October 2016

Antibiotics in food systems at the 'N8 AgriFood Launch 2016: One Network, Many Solutions' Conference: 21-22 June 2016

'Understanding Bacteria' workshop: 26 February 2016

'Biomarkers and rapid diagnostics to address the AMR challenge' Workshop: 2 December 2015

'Industry Communication Training': 16 November 2015

'TARGeTED Collaboration Building' Workshop (project kick-off meeting): 6-7 May 2015

Seminar Series:

Public engagement and outreach

Our researchers spoke about Antimicrobial resistance at the following events receiving positive feedback and interesting questions from the audience.

Funding opportunities

‌Funding opportunities

Pump Priming Fund

The second call for TARGeTED Pump Priming is now closed. View the summaries of the successful projects here


Longitude Prize: How can we prevent the rise of resistance to antibiotics?

The Challenge: create a cost-effective, accurate, rapid and easy-to-use test for bacterial infections that will allow health professionals worldwide to administer the right antibiotics at the right time. 

The Prize: £10 million

Entries: anytime until 30 September 2019

Research

Research to combat AMR at York

The threat of the rise of antimicrobial resistance (AMR) has been recognised as one of todays global Grand Challenges alongside food security and climate change.

In recent years there has been a galvanisation of public awareness, political activity and action in research in this area. At the University of York, we have built a thriving and active community of researchers in the AMR field, addressing the following:

  • Medicines to combat tropical diseases
  • Understanding resistant bacteria and how they evolve
  • Identification of novel targets for new drugs
  • Refreshing the pipeline for new antimicrobials
  • Developing multidisciplinary approaches to tackle diagnostics
  • Socio-economic research into AMR
  • Public engagement and teaching students in antibiotic discovery

AMR Research at York (PDF  , 2,539kb)

View the summaries of the TARGeTED pump priming research projects funded so far


Latest news:


How bacteria share their superbug traits

Research carried out by biologists at York takes us a step closer to understanding the rise of antibiotic-resistant superbugs, one of the world’s most pressing global health challenges.

By studying bacteria in soil samples, the York researchers found that genes for traits such as antibiotic resistance can be spread by particular types of molecule known as infectious plasmids.

Bacteria growing in mixed populations of more than one species allowed the plasmids to broadcast genetic information across the bacterial ‘community’ – and this could include traits that enable bacteria to develop resistance to antibiotics.

View the full news item


Developing the tools to find new generation antibiotics

Research led by Professor Maggie Smith (Principal Investigator on TARGeTED) in the Department of Biology at York will provide new tools for creating stable genetically engineered strains which could lead to improvements to existing antibiotics and the development of new ones.

The study, published in Applied and Environmental Microbiology, used novel genetic engineering tools to manipulate the genes required for antibiotic biosynthesis. The new tools will enable scientists to create new antibiotics.

View the full news item on the Biology pages


Artistic exploration of University of York's hunt for new antimicrobials - artistis in residence scheme

Internationally renowned artist Anna Dumitriu will collaborate with Professor Maggie Smith to explore the urgent issue of antibiotic resistance and the research being undertaken at the University of York in the hunt for new antimicrobials. The residency will lead to a new body of artwork and there will also be a participatory public workshop to communicate new research and reflect on the current and future impact of antibiotic resistance with a diverse, non-scientific audience. The residency is funded by C2D2 and TARGeTED.

View the full news item on the C2D2 website

 

Links

Useful Links

External websites

 

Useful documents

Contact us

Contact Us

For all queries contact Wendy Burns, TARGeTED Project Administrator.

Email: targeted-project@york.ac.uk

Telephone: 01904 567604 (internal 956 7604)

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Postal address:

Research Innovation Office
Suite 1.14
Innovation Centre
York Science Park
University of York
Heslington
York, YO10 5DG 


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