Medicinal Chemistry

Year 2, Spring Term

Dr. Paul A. Clarke, Room C170

                         

                          Course Handouts: Please download a copy before the first lecture.

 

                          Further Reading on Selected Case Studies

 

                               Losartan

                               Perspective on Angiotensin-II receptor antagonists

                              

                               Antagonists of histamine

                               James Black’s Nobel Lecture

                               Review of histamine H2 antagonists

 

                               Oseltamivir Phosphate (Tamifu®)

                               Roche synthesis

                               Rohloff synthesis

                               Corey synthesis

                               Shibasaki synthesis

                              

                               Zidovudine (AZT)

                               Mesylates of (2’-deoxy-lyxofuranosyl)thymine

                               Further synthetic studies

 

                               Sildenafil Citrate (ViagraTM)

                               Pfizer Synthesis

 

                               Papers on Current and Future Strategies

                               Analysis of reactions used in industry

                               Diversity oriented synthesis