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Scientists step closer to drug treatment for Hepatitis B

Posted on 22 June 2017

A major new insight into how Hepatitis B virus works could pave the way for new drug treatments for the infection, which is the major cause of liver cancer worldwide.

The team (including Prof Reidun Twarock from the Departments of Mathematics and Biology) at the Universities of York and Leeds identified an “assembly code” in the genetic material of Hepatitis B virus that allows it to create a protective casing in which it can produce new infectious virus particles. 

They found that the signal, generated by ribonucleic acid (RNA), helps viral proteins to overcome an ‘engineering problem’, assembling them into in a particular geometric pattern.

The full story is available on the University's news page.