York Trials Unit (YTU) was established in 1996 as a dedicated trials unit within the Department of Health Sciences at the University of York. Over the last 21 years we have undertaken 130 randomised controlled trials, including those still on-going, and staffing has grown from around 10 staff to over 60 with an array of skills and expertise.
Our clinical trials cover a broad range of areas including: musculoskeletal problems; surgery; chronic wounds; falls prevention; addiction; mental health; and infectious diseases. Our expertise in designing and supporting complex trials has been recognised by the Royal College of Surgeons and supported by the British Orthopaedic Association where we are one of seven surgical trials units in the UK, with a specialist interest in orthopaedic trials. Many of the trials have had a huge impact on clinical practice and informed national and international guidelines for the benefit of patients.
We have led or supported trials in the area of social sciences, including trials in education, crime and justice, and political science. YTU has also supported the Cabinet Office in its trials agenda.
We also undertake methodological randomised trials within trials (i.e., embedded studies) which have led to changes to the conduct of trials more generally.
In recognition of YTU’s 21st Birthday, we hosted a celebratory event. Key speakers included, Professor Hywel Williams, Director of the NIHR HTA programme, Professor Ian Russell, founder of the Unit, and Professor Koen Lamberts, Vice Chancellor of the University of York. Staff and colleagues all came together to celebrate the achievements of the team at YTU.