YCIL Academics

Professor Martin Bees

Dept of Mathematics

 

Martin was appointed the Anniversary Chair of Mathematics in 2012. His research interests lie at the boundaries between mathematical biology, fluid dynamics and biological physics, where he develops theoretical and experimental tools in tandem to unravel mechanisms. He explores the mathematics of living suspensions, such as describing dispersion and pattern formation of biased swimming micro-organisms in bioreactors, bacterial swarming in thin films and designing novel theoretical approaches for high-throughput assays of cell motility. Martin also has interests in the mathematics of speciation, agricultural pest control, plankton patch dynamics, algal hydrogen production, the human photopic electroretinogram and applicable models of wound healing.
 

Professor Mark Coles

Centre for Immunology & Infection

Mark’s research focuses on understanding how lymphoid tissues (lymph nodes, spleen, gut associated lymphoid tissue and thymus) develop and function with a focusing on the role of stromal cells in immune responses. To understand the physiology of immune homeostasis and response to infectious disease his laboratory uses a number of different approaches including multi-photon imaging, artificial tissue engineered immune tissues and systems immunology. Mark has collaborated with Jon on a number of different modelling projects including simulating vascular function in immune responses, development of lymphoid tissues and development of clinically relevant simulations of autoimmune disease. Research in the Coles laboratory is funded by the Human Frontiers Science Program.
 

Professor Paul Kaye

Centre for Immunology & Infection

Paul is a cellular immunologist whose main interest has been in the interface between antigen presenting cell biology and immune-mediated pathology. He has combined this with the study of one of the great neglected tropical diseases, visceral leishmaniasis. After moving to York, Paul began collaborating with Jon Timmis with the aim of applying computational approaches to understand granulomatous inflammation, one of the cardinal features of many chronic inflammatory diseases. Paul is a Wellcome Trust Senior Investigator and a Fellow of the Academy of Medical Sciences. He leads the NC3Rs / Innovate UK-funded CRACK-IT Challenge in virtual infectious diseases.

Dr Marika Kullberg

Centre for Immunology & Infection

Marika is a cellular immunologist, and her research focuses on the immunology of intestinal inflammation and the mechanisms by which immune responses are initiated and regulated in the intestinal tract. Marika is collaborating with Jon Timmis and Mark Coles to develop a computational in silico model of intestinal inflammation with the aim of contributing to our understanding of the immunological processes active in the human gastrointestinal tract during inflammatory bowel disease.

Dr Dimitris Lagos

Centre for Immunology & Infection

Dimitris' research focuses on the functions of microRNAs and RNA-binding proteins in mammalian cells. The main goals of his group are to understand how RNA-driven molecular networks contribute to disease and to identify therapeutic opportunities within these disease-associated networks. Towards this, Dimitris is collaborating with Jon Timmis aiming to develop agent-based simulations of the behaviour of microRNA-driven molecular networks during infection of primary human cells. Dimitris is an MRC New Investigator Research Grant holder. The lab is also funded by the Wellcome Trust, the BBSRC, and the Centre for Chronic Diseases and Disorders.

 

Dr Fiona Polack

Dept of Computer Science

Fiona is a Senior Lecturer in York Centre for Complex Systems Analysis and the Non-standard Computation group of Department of Computer Science. In 1999 and 2001, she held short appointments as a research fellow at Conservatoire des Arts et Metiers, Evry, France. Her main research is focused on software modelling, complex systems simulation and validation of complex systems. She has over 100 conference and journal papers on aspects of software engineering and non-standard computation.

Professor Jon Timmis

Dept of Electronics

Jon is an Engineer and interdisciplinary researcher, developing computational models of immune function (computational immunology), or fault-tolerance achieved via bio-inspired engineering with a focus on the immune system (immuno-engineering). Jon has held a Royal Society-Wolfson Research Merit award, a senior research fellowship of the Royal Society, during which time he developed the computational immunology work at York, and held a Royal Academy of Engineering Enterprise Fellowship to work on the commercialisation of auto-immune disease modelling tools, in collaboration with Dr Mark Coles. He is currently the Head of the Department of Electronics