Tel: (+44) (0)1904 32 8276
Mia is a Postdoctoral Research Associate working with Dr Lianne Willems at the York Structural Biology Laboratory. Previously, Mia investigated how the ionic tumour microenvironment impacts checkpoint protein expression in cancer cells with Dr Dimitris Lagos and Dr William Brackenbury at the University of York. She completed her PhD in Pharmacology from Columbia University in 2017 where she developed new fluorescent labeling and live cell imaging methods for studying human cardiac voltage-gated sodium channels.
Her current project focuses on investigation of mammalian phosphoribitol transferases using novel labelling and activity probes. Genetic mutation of these enzymes result in aberrant glycosylation of their targets, resulting in a variety of congenital muscular dystrophies. This work will further our understanding of this glycosylation pathway, providing much needed insight on the underlying mechanisms of clinically relevant mutations.