Magnetic Resonance and Hyperpolarisation

The study of molecules and materials by magnetic resonance has had a very significant scientific impact and diverse utilisation. The research activities pursued in this theme include: the use of hyperpolarisation to overcome the low sensitivity of magnetic resonance in order to open up new applications in molecular sensing and clinical imaging; the use of EPR to characterise the properties and reactivity of nanostrucutres; the development of ab initio calculations of NMR parameters for large molecules; and the exploitation of nuclear spin dynamics as a platform for unconventional computation. The Centre for Hyperpolarisation in Magnetic Resonance (CHyM) is dedicated to harnessing a recent York advancement, the Signal Amplification by Reversible Exchange method, which produces a 100,000-fold improved magnetic resonance response such that low concentrations of metabolites, drugs and many other small molecules can be optimally detected. The centre is working towards producing solutions to real-world problems in fundamental science, healthcare, and industry. It supports an interdisciplinary team of academics that have research interests in catalysis, photochemistry, complex organic synthesis, biochemistry, analytical science, magnetic resonance, and medicine to achieve this.

People

  • Martin Cockett - High-resolution laser spectroscopy with electrons and ions 
  • Simon Duckett - Organometallic chemistry and reaction mechanisms
  • Ian Fairlamb - Transition metals in synthesis, catalysis and chemical biology: reactivity, mechanism and applications
  • Meghan Halse - Nuclear Magnetic Resonance (NMR) Spectroscopy
  • Aneurin KennerleyNeuroimaging
  • Robin Perutz - Organometallic Photochemistry, Small Molecule Activation, Catalysis and Solar Fuels
  • Angelika Sebald - Nuclear magnetic resonance spectroscopy