Use of real world evidence in health technology assessment

Tuesday 21 August 2018, 11.00AM12.00pm

Speaker(s): Professor Keith Abrams, University of Leicester

Abstract: In this talk the possible situations in which Real World Evidence (RWE), both comparative and single arm studies, could be included in a Meta-Analysis or Network Meta-Analysis (NMA) will be described and discussed. These include; sparse networks, disconnected networks, multiple outcome networks, and the use of such NMAs in terms of decision making and designing future Randomised Controlled Trials (RCTs). In particular, methods for the allowance of potential biases and selection effects associated with RWE and how these may also be incorporated into NMAs will be discussed. The methods will be illustrated using examples in Multiple Sclerosis and Rheumatoid Arthritis from the IMI GetReal Project, as well as examples on Statin use and subsequent risk of diabetes. 

Location: Alcuin A Block A019/20

Who to contact

For more information on these seminars, contact:

Thomas Patton
thomas.patton@york.ac.uk
Dina Jankovic
dina.jankovic@york.ac.uk

Economic evaluation seminar dates

  • Wednesday 31 October
    Professor Julie Ratcliffe, University of South Australia
  • Thursday 15 November 
    Dr Alexina Mason,
    London School of Hygiene and Tropical Medicine