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Publications are listed with the most recent first, and authors who were in the group at the
time the work was done are in bold. Where possible, clicking a title will take you to the PubMed entry for the article.
R.A. Wilson, J.A.M Langermans, G.J. Van Dam, R.A. Vervenne, S.L. Hall, W.C. Borges, G.P. Dillon, A.W. Thomas, and P.S. Coulson (2008).
Elimination of Schistosoma mansoni Adult Worms by Rhesus Macaques: Basis for a Therapeutic Vaccine? PLOS Neglected Tropical Diseases:
2(9): e290.
T.M Kariuki, I.O. Farah, R.A. Wilson, and P.S. Coulson (2008).
Antibodies elicited by the secretions from schistosome cercariae and eggs are predominantly against glycan epitopes Parasite Immunol.:
30(10): 554-562.
G.P. Dillon, T. Feltwell, J.P. Skelton, P.S. Coulson, R.A. Wilson and A.C. Ivens (2008).
Altered patterns of gene expression underlying the enhanced immunogenicity of radiation-attenuated schistosomes. PLOS Neglected Tropical Diseases:
2(5): e240.
G.P. Dillon, J.C. Illes, H.V. Issacs and R.A. Wilson (2007).
Patterns of gene expression in schistosomes: localisation by whole mount in situ hybridisation Parasitology:
134(11): 1589-1597.
J. Jang-Lee, R.S. Curwen, P.D. Ashton, B. Tissot, W. Mathieson, M. Panico, A. Dell, R.A. Wilson and S.M. Haslam (2007).
Glycomics analysis of Schistosoma mansoni egg and cercarial secretions. .Mol Cell Proteomics:
6(9): 1485-1499.
R. DeMarco, W. Mathieson, G.P. Dillon and R.A. Wilson (2007).
Schistosome albumin is of host not parasite origin. International Journal for Parasitology:
37(11): 1201-1208.
W. Castro-Borges, J. Cartwright, P.D. Ashton, S. Braschi, R. Guerra Sa, V. Rodrigues, R.A. Wilson and R.S. Curwen (2007).
The 20S proteasome of Schistosoma mansoni: a proteomic analysis. Proteomics:
7(7): 1065-1075.
J.H. Keating, R.A. Wilson and P.J. Skelly (2007).
No Overt Cellular Inflammation around Intravascular Schistosomes in vivo Journal of Parasitology:
92(6): 1365-1369.
R.A. Wilson, P.D. Ashton, S. Braschi, G.P. Dillon, M. Berriman and A. Ivens (2007).
'Oming in on schistosomes: prospects and limitations for post-genomics. Trends Parasitol.:
23(1): 14-20.
P.J. Skelly and R.A. Wilson (2006).
Making Sense of the Schistosome surface. Adv. Parasitol.:
63(): 185-284.
R.S. Curwen, P.D. Ashton, S. Sundaralingam and R.A. Wilson (2006).
Identification of novel proteases and immunomodulators in the secretions of schistosome cercariae that facilitate host entry. Mol. Cell. Proteomics.:
5(5): 835-844.
S. Braschi, and R.A. Wilson (2006).
Proteins exposed at the adult schistosome surface revealed by biotinylation. Mol. Cell. Proteomics.:
5(2): 347-356.
S. Braschi, R.S. Curwen, P.D. Ashton, S. Verjovski-Almeida, and R.A. Wilson (2006).
The tegument surface membranes of the human blood parasite Schistosoma mansoni: a proteomic analysis after differential extraction. Proteomics:
6(5): 1471-1482.
G.P. Dillon, T. Feltwell, J.P. Skelton, P.D. Ashton, P.S. Coulson, M.A. Quail, N. Nikolaidou-Katsaridou, R.A. Wilson and A.C. Ivens (2006).
Microarray analysis identifies genes preferentially expressed in the lung schistosomulum of Schistosoma mansoni. International Journal for Parasitology:
36(1): 1-8.
S. Braschi, W.C. Borges, and R.A. Wilson (2006).
Proteomic analysis of the schistosome tegument and its surface membranes. Memorias do Instituto Oswaldo Cruz:
101(Suppl. 1): 205-212.
R.A. Wilson, G.J. Van Dam, T.M. Kariuki, I.O. Farah, A.M. Deelder and P.S. Coulson, (2006).
The detection limits for estimates of infection intensity in schistosomiasis mansoni established by a study in non-human primates. International Journal for Parasitology:
36(12): 1241-1244.
T.M. Kariuki, G.J. Van Dam, A.M. Deelder, I.O. Farah, D.S. Yole, R.A. Wilson and P.S. Coulson (2006).
Previous or ongoing schistosome infections do not compromise the efficacy of the attenuated cercaria vaccine. Infect Immun.:
74(7): 3979-3986.
R.A. Wilson and P.S. Coulson (2006).
Schistosome vaccines: a critical appraisal. Memorias do Instituto Oswaldo Cruz 101(Suppl. 1): 13-20.
R.A. Wilson and P.S. Coulson (2006).
The Development of a Schistosome Vaccine. In: Parasitic Flatworms: Molecular Biology, Biochemistry, Immunology and Physiology Eds A.G. Maule and N.J. Marks CAB International.
R.S. Curwen, R S., P.D. Ashton, D.A. Johnson, and R.A. Wilson, R A (2004).
The Schistosoma mansoni proteome: a comparison across four life cycle stages. Mol. Biochem. Parasitol.:
138(1): 57-66.
T.M. Kariuki, I.O. Farah, D.S. Yole, J.M. Mwenda, G. Van Dam, A.M. Deelder, R.A. Wilson and P.S. Coulson (2004).
Parameters of the Attenuated Schistosome Vaccine Evaluated in the Olive Baboon. Inf. & Immun.:
72(9): 5526-5529.
R.A. Wilson, R.S. Curwen, S. Braschi, S.L. Hall, P.S. Coulson and
P.D. Ashton (2004). From Genomes to Vaccines via the Proteome.
Memorias do Instituto Oswaldo Cruz: 99(Suppl. 1): 45-50.
A.P. Mountford and S.J. Jenkins (2004). Vaccine
development: Lessons from the study of initial immune responses to invading
larvae. In: Schistosomiasis. Eds. W. E. Secor and D. G. Colley,
Kluwer Academic Publishers. World Class Parasites vol. 9.
A.P. Mountford and F. Trottein (2004).
Schistosomes in the skin:
a balance between immune priming and regulation. Trends in Parasitology:
20(5): 221-226.
S.J. Jenkins and A.P. Mountford (2004). Ligation of CD40
reverses the capacity of dendritic cells primed with larval secretions of
Schistosoma mansoni to drive Th2-type cytokine production. European
Journal of Immunology: Submitted.
R. DeMarco, A.T. Kowaltowski, A.A. Machado, M.B. Soares,
C. Gargioni, T. Kawano, V. Rodrigues, A.M. Madeira, R.A. Wilson, C.F. Menck,
J.C. Setubal, E. Dias-Neto, L.C. Leite and S. Verjovski-Almeida (2004).
Saci-1, -2, and -3 and Perere, four novel retrotransposons with high
transcriptional activities from the human parasite Schistosoma mansoni. J
Virol 78(6): 2967-2978.
P. Kourilova, K.G. Hogg, L. Kolarova
and A.P. Mountford (2004).
Cercarial dermatitis caused by bird schistosomes
comprises both immediate and late phase cutaneous hypersensitivity
reactions. J Immunol 172(6): 3766-3774.
R.S. Curwen and R.A. Wilson (2003).
Invasion of skin by schistosome
cercariae: some neglected facts. Trends Parasitol 19(2):
63-66; discussion 66-68.
S. Schmitz, C.J. Schankin, H. Prinz, R.S. Curwen, P.D. Ashton,
L.S.D. Caves, R.H.A. Fink, J.C. Sparrow, P.J. Mayhew and C. Veigel (2003).
Molecular evolutionary convergence of the flight muscle protein arthrin in
diptera and hemiptera. Molecular Biology and Evolution 20(12):
2019-2033.
L.B. Murphy, C. Loney, L. Murray, D. Bhella, P. Ashton and R.P.
Yeo (2003).
Investigations into the amino-terminal domain of the respiratory
syncytial virus nucleocapsid protein reveal elements important for
nucleocapsid formation and interaction with the phosphoprotein. Virology
307(1): 143-153.
K.G. Hogg, S. Kumkate, S. Anderson and A.P. Mountford (2003).
Interleukin-12 p40 secretion by cutaneous CD11c+ and F4/80+ cells is a major
feature of the innate immune response in mice that develop Th1-mediated
protective immunity to Schistosoma mansoni. Infect Immun 71(6):
3563-3571.
K.G. Hogg, S. Kumkate and A.P. Mountford (2003).
IL-10 regulates early
IL-12-mediated immune responses induced by the radiation-attenuated
schistosome vaccine. Int Immunol 15(12): 1451-1459.
S.A. Linehan, P.S. Coulson, R.A. Wilson, A.P. Mountford, F. Brombacher,
L. Martinez-Pomares and S. Gordon (2003).
IL-4 receptor signaling is
required for mannose receptor expression by macrophages recruited to
granulomata but not resident cells in mice infected with Schistosoma
mansoni. Lab Invest 83(8): 1223-1231.
C.H. Sadler, L.I. Rutitzky, M.J. Stadecker and R.A. Wilson (2003).
IL-10
is crucial for the transition from acute to chronic disease state during
infection of mice with Schistosoma mansoni. Eur J Immunol 33(4):
880-888.
S. Verjovski-Almeida, R. DeMarco, E.A. Martins, P.E. Guimaraes, E.P.
Ojopi, A.C. Paquola, J.P. Piazza, M.Y. Nishiyama, Jr., J.P. Kitajima, R.E.
Adamson, P.D. Ashton, M.F. Bonaldo, P.S. Coulson, G.P. Dillon, L.P. Farias,
S.P. Gregorio, P.L. Ho, R.A. Leite, L.C. Malaquias, R.C. Marques, P.A.
Miyasato, A.L. Nascimento, F.P. Ohlweiler, E.M. Reis, M.A. Ribeiro, R.G. Sa,
G.C. Stukart, M.B. Soares, C. Gargioni, T. Kawano, V. Rodrigues, A.M.
Madeira, R.A. Wilson, C.F. Menck, J.C. Setubal, L.C. Leite and E. Dias-Neto
(2003).
Transcriptome analysis of the acoelomate human parasite Schistosoma
mansoni. Nat Genet 35(2): 148-157.
C.F. Brito, G.C. Oliveira, S.C. Oliveira, M. Street, S. Riengrojpitak,
R.A. Wilson, A.J. Simpson and R. Correa-Oliveira (2002).
Sm14 gene
expression in different stages of the Schistosoma mansoni life cycle and immunolocalization of the Sm14 protein within the adult worm. Braz J Med
Biol Res 35(3): 377-381.
S.U. Busek, M. Fantappie, L.C. Malaquias, R.A. Wilson, R. Correa-Oliveira
and G.C. Oliveira (2002).
Cis-acting elements, CArG-, E-, CCAAT- and TATA-boxes
may be involved in sexually regulated gene transcription in Schistosoma
mansoni. Mem Inst Oswaldo Cruz 97 Suppl 1: 85-90.
J.E. Crabtree, M. Court, M.M. Walker, J.T. Wang, P.S. Coulson, S.
Coggle, P.A. Robinson and J.L. Telford (2002). The effects of chronic
schistosomiasis on murine Helicobacter gastric epithelial cell
proliferation. Gastroenterology 122(4): M873.
M. Eberl, M. al-Sherbiny, P. Hagan, S. Ljubojevic, A.W. Thomas and
R.A. Wilson (2002).
A novel and sensitive method to monitor helminth infections
by faecal sampling. Acta Trop 83(2): 183-187.
A. Teixeira-Carvalho, O.A. Martins-Filho, Z.A. Andrade, J.R. Cunha-Mello,
R.A. Wilson and R. Correa-Oliveira (2002).
The study of T-cell activation in
peripheral blood and spleen of hepatosplenic patients suggests an exchange
of cells between these two compartments in advanced human Schistosomiasis
mansoni infection. Scand J Immunol 56(3): 315-322.
P.D. Ashton, R.S. Curwen and R.A. Wilson (2001).
Linking proteome and
genome: how to identify parasite proteins. Trends Parasitol 17(4):
198-202.
P.D. Ashton, R. Harrop, B. Shah and R.A. Wilson
(2001).
The schistosome
egg: development and secretions. Parasitology 122(Pt 3):
329-338.
J.E. Crabtree, M. Court, M.M. Walker, P.S. Coulson, S. Coggle, P.A.
Robinson, D. Sosnoskwa and J.L. Telford (2001). The effects of chronic
schistosomiasis on murine Helicobacter induced gastritis.
Gastroenterology 120(5): 3815.
M. Eberl, J.A. Langermans, R.A. Vervenne, A.K. Nyame, R.D. Cummings, A.W.
Thomas, P.S. Coulson and R.A. Wilson (2001).
Antibodies to glycans dominate
the host response to schistosome larvae and eggs: is their role protective
or subversive? J Infect Dis 183(8): 1238-1247.
A.P. Mountford, K.G. Hogg, P.S. Coulson and F. Brombacher (2001).
Signaling via interleukin-4 receptor alpha chain is required for successful
vaccination against schistosomiasis in BALB/c mice. Infect Immun
69(1): 228-236.
D.W. Dunne and A.P. Mountford (2001). Resistance to Infection in
Human and Animal Models. In: Schistosomiasis. A. A. F. Mahmoud.
London, Imperial College Press.
P. Carneiro-Santos, O. Martins-Filho, L.F. Alves-Oliveira, A.M. Silveira,
P. Coura-Filho, I.R. Viana, R.A. Wilson and R. Correa-Oliveira (2000).
Apoptosis: a mechanism of immunoregulation during human Schistosomiasis
mansoni. Parasite Immunol 22(6): 267-277.
M. Eberl, E. Beck, P.S. Coulson, H. Okamura, R.A. Wilson
and A.P.
Mountford (2000).
IL-18 potentiates the adjuvant properties of IL-12 in the
induction of a strong Th1 type immune response against a recombinant
antigen. Vaccine 18(19): 2002-2008.
P. Hagan, M.J. Doenhoff, R.A. Wilson, M. Al-Sherbiny and R. Bergquist
(2000).
Schistosomiasis vaccines: a response to a devils' advocate's view.
Parasitol Today 16(8): 322-323.
R. Harrop, N. Jennings, A.P. Mountford, P.S. Coulson
and R.A. Wilson
(2000).
Characterization, cloning and immunogenicity of antigens released by
transforming cercariae of Schistosoma mansoni. Parasitology 121 (
Pt 4): 385-394.
J.J. Lee, K.A. Sinha, J.A. Harrison, R.D. de Hormaeche, G. Riveau, R.J.
Pierce, A. Capron, R.A. Wilson and C.M. Khan (2000).
Tetanus toxin fragment
C expressed in live Salmonella vaccines enhances antibody responses to its
fusion partner Schistosoma haematobium glutathione S-transferase. Infect
Immun 68(5): 2503-2512.
S. Anderson, P.S. Coulson, S. Ljubojevic, A.P. Mountford
and R.A. Wilson
(1999).
The radiation-attenuated schistosome vaccine induces high levels of
protective immunity in the absence of B cells. Immunology 96(1):
22-28.
S. Anderson, V.L. Shires, R.A. Wilson and A.P. Mountford
(1999).
Formation of multinucleated giant cells in the mouse lung is promoted in the
absence of interleukin-12. Am J Respir Cell Mol Biol 20(3):
371-378.
M. Eberl, A.P. Mountford, D. Jankovic and E. Beck (1999).
Isolation of
T-cell antigens by using a recombinant protein library and its application
to the identification of novel vaccine candidates against schistosomiasis.
Infect Immun 67(7): 3383-3389.
R. Harrop, P.S. Coulson and R.A. Wilson (1999).
Characterization, cloning
and immunogenicity of antigens released by lung-stage larvae of Schistosoma
mansoni. Parasitology 118 ( Pt 6): 583-594.
A.P. Mountford, P.S. Coulson, A.W. Cheever, A. Sher, R.A. Wilson
and T.A.
Wynn (1999).
Interleukin-12 can directly induce T-helper 1 responses in
interferon-gamma (IFN-gamma) receptor-deficient mice, but requires IFN-gamma
signalling to downregulate T-helper 2 responses. Immunology 97(4):
588-594.
M. Street, P.S. Coulson, C. Sadler, L.J. Warnock,
D. McLaughlin, H. Bluethmann and R.A. Wilson (1999).
TNF is essential for the cell-mediated
protective immunity induced by the radiation-attenuated schistosome vaccine.
J Immunol 163(8): 4489-4494.
R.A. Wilson and P.S. Coulson (1999).
Strategies for a schistosome
vaccine: can we manipulate the immune response effectively? Microbes
Infect 1(7): 535-543.
R.A. Wilson, P.S. Coulson and A.P. Mountford (1999).
Immune responses to
the radiation-attenuated schistosome vaccine: what can we learn from
knock-out mice? Immunol Lett 65(1-2): 117-123.
S. Anderson, V.L. Shires, R.A. Wilson and A.P. Mountford
(1998).
In the
absence of IL-12, the induction of Th1-mediated protective immunity by the
attenuated schistosome vaccine is impaired, revealing an alternative pathway
with Th2-type characteristics. Eur J Immunol 28(9): 2827-2838.
C.J. Betts and R.A. Wilson (1998).
Th1 cytokine mRNA expression dominates
in the skin-draining lymph nodes of C57BL/6 mice following vaccination with
irradiated Schistosoma mansoni cercariae, but is down-regulated upon
challenge infection. Immunology 93(1): 49-54.
R. Correa-Oliveira, L.C. Malaquias, P.L. Falcao, I.R. Viana, L.M.
Bahia-Oliveira, A.M. Silveira, L.A. Fraga, A. Prata, R.L. Coffman, J.R.
Lambertucci, J.R. Cunha-Melo, O.A. Martins-Filho, R.A. Wilson and G. Gazzinelli (1998).
Cytokines as determinants of resistance and pathology in
human Schistosoma mansoni infection. Braz J Med Biol Res 31(1):
171-177.
P.S. Coulson, L.E. Smythies, C. Betts, N.A. Mabbott, J.M. Sternberg, X.G.
Wei, F.Y. Liew and R.A. Wilson (1998).
Nitric oxide produced in the lungs of mice immunized with the
radiation-attenuated schistosome vaccine is not the major agent causing
challenge parasite elimination. Immunology 93(1):
55-63.
D. Imbert-Establet, H. Mone, P.S. Coulson and R.A. Wilson (1998).
Schistosome-induced portacaval haemodynamic changes in Rattus rattus are
associated with translocation of adult worms to the lungs. Parasitology
116 ( Pt 3): 237-241.
A. Lane, D. Boulanger, G. Riveau, A. Capron and R.A. Wilson (1998).
Murine immune responses to Schistosoma haematobium and the vaccine candidate
rSh28GST. Parasite Immunol 20(8): 359-367.
N. Mabbott, P. Coulson, L. Smythies, R. Wilson and
J. Sternberg (1998).
African trypanosome infections in mice that lack the interferon-gamma
receptor gene: nitric oxide-dependent and -independent suppression of T-cell
proliferative responses and the development of anaemia. Immunology
94(4): 476-480.
A.P. Mountford and E. Pearlman (1998).
Interleukin-12 and the host
response to parasitic helminths; the paradoxical effect on protective
immunity and immunopathology. Parasite Immunol 20(11):
509-517.
A.P. Mountford, V.L. Shires and S. Anderson (1998).
Interleukin-12 and
protective immunity to schistosomes. Braz J Med Biol Res 31(1):
163-169.
S. Riengrojpitak, S. Anderson and R.A. Wilson (1998).
Induction of
immunity to Schistosoma mansoni: interaction of schistosomula with accessory
leucocytes in murine skin and draining lymph nodes. Parasitology
117 ( Pt 4): 301-309.
R.A. Wilson (1998).
Interferon gamma is a key cytokine in lung phase
immunity to schistosomes but what is its precise role? Braz J Med Biol
Res 31(1): 157-161.
P.S. Coulson (1997). The radiation-attenuated vaccine against
schistosomes in animal models: Paradigm for a human vaccine? Advances in
Parasitology 39: 271-336.
P.S. Coulson and R.A. Wilson (1997).
Recruitment of lymphocytes to the
lung through vaccination enhances the immunity of mice exposed to irradiated
schistosomes. Infect Immun 65(1): 42-48.
L. Cutts and R.A. Wilson (1997).
The protein antigens secreted
in vivo by
adult male Schistosoma mansoni. Parasitology 114 ( Pt 3):
245-255.
L. Cutts and R.A. Wilson (1997).
Elimination of a primary schistosome
infection from rats coincides with elevated IgE titres and mast cell
degranulation. Parasite Immunol 19(2): 91-102.
E.D. Neto, R. Harrop, R. Correa-Oliveira, R.A. Wilson, S.D. Pena and A.J.
Simpson (1997).
Minilibraries constructed from cDNA generated by arbitrarily
primed RT-PCR: an alternative to normalized libraries for the generation of
ESTs from nanogram quantities of mRNA. Gene 186(1): 135-142.
G. Franco, E. Rabelo, V. Azevedo, H. Pena, J. Ortega, T. Santos, W. Meira,
N. Rodrigues, C. Dias, R. Harrop, A. Wilson, M. Saber, H. Abdel-Hamid, M.
Faria, M. Margutti, J. Parra and S. Pena (1997).
Evaluation of cDNA
libraries from different developmental stages of Schistosoma mansoni
for production of expressed sequence tags (ESTs). DNA Res 4(3):
231-240.
E. Dias Neto, R. Harrop, R. Correa-Oliveira, S.D. Pena, R.A. Wilson
and A.J. Simpson (1996).
The schistosome genome project: RNA arbitrarily primed PCR allows the accelerated generation of expressed sequence tags. Mem
Inst Oswaldo Cruz 91(5): 655-657.
A.P. Mountford, S. Anderson and R.A. Wilson (1996).
Induction of Th1
cell-mediated protective immunity to Schistosoma mansoni by
co-administration of larval antigens and IL-12 as an adjuvant. J Immunol
156(12): 4739-4745.
L.E. Smythies, C. Betts, P.S. Coulson, M.A. Dowling
and R.A. Wilson
(1996).
Kinetics and mechanism of effector focus formation in the lungs of
mice vaccinated with irradiated cercariae of Schistosoma mansoni.
Parasite Immunol 18(7): 359-369.
R.A. Wilson, P.S. Coulson, C. Betts, M.A. Dowling
and L.E. Smythies (1996).
Impaired immunity and altered pulmonary responses in mice with a
disrupted interferon-gamma receptor gene exposed to the irradiated
Schistosoma mansoni vaccine. Immunology 87(2): 275-282.
A.P. Mountford, R. Harrop and R.A. Wilson (1995).
Antigens derived from
lung-stage larvae of Schistosoma mansoni are efficient stimulators of
proliferation and gamma interferon secretion by lymphocytes from mice
vaccinated with attenuated larvae. Infect Immun 63(5):
1980-1986.
G.F. Newlands, P.S. Coulson and R.A. Wilson (1995).
Stem cell factor dependent hyperplasia of mucosal-type mast cells but not
eosinophils in
Schistosoma mansoni-infected rats. Parasite Immunol 17(11):
595-598.
R.M. Pemberton and R.A. Wilson (1995).
T-helper type-1-dominated lymph
node responses induced in C57BL/6 mice by optimally irradiated cercariae of
Schistosoma mansoni are down-regulated after challenge infection.
Immunology 84(2): 310-316.
H.R. Miller, G.F. Newlands, A. McKellar, L. Inglis, P.S. Coulson and
R.A.
Wilson (1994).
Hepatic recruitment of mast cells occurs in rats but not mice
infected with Schistosoma mansoni. Parasite Immunol 16(3):
145-155.
A.P. Mountford, A. Fisher and R.A. Wilson (1994).
The profile of IgG1 and
IgG2a antibody responses in mice exposed to Schistosoma mansoni. Parasite
Immunol 16(10): 521-527.
R.M. Pemberton, L.C. Malaquias, P.L. Falcao, A.M. Silveira, A.L. Rabello,
N. Katz, M. Amorim, A.P. Mountford, R.L. Coffman, R. Correa-Oliveira and et
al. (1994).
Cell-mediated immunity to schistosomes. Evaluation of mechanisms
operating against lung-stage parasites which might be exploited in a
vaccine. Trop Geogr Med 46(4 Spec No): 247-254.
N. Saunders, P.S. Coulson, R.A. Wilson, N. De Jonge, F.W. Krijger and M.
Deelder (1994).
A model system for the study of antigen secretion by adult
Schistosoma mansoni in vivo. Parasitol Res 80(2): 154-158.
P.S. Coulson, L.E. Smythies and R.A. Wilson (1993).
Pulmonary
granulomatous hypersensitivity: cell-mediated responses to embolized
schistosome larvae and eggs. Reg Immunol 5(3-4): 165-173.
P.S. Coulson, L.E. Smythies and R.A. Wilson (1993).
Functional and
phenotypic properties of the CD4+ T cell population in a murine pulmonary
delayed-type hypersensitivity response. Chest 103(2 Suppl):
138S.
P.S. Coulson and R.A. Wilson (1993).
Pulmonary T helper lymphocytes are
CD44hi, CD45RB- effector/memory cells in mice vaccinated with attenuated
cercariae of Schistosoma mansoni. J Immunol 151(7): 3663-3671.
R. Harrop and R.A. Wilson (1993).
Protein synthesis and release by
cultured schistosomula of Schistosoma mansoni. Parasitology 107 (
Pt 3): 265-274.
R. Harrop and R.A. Wilson (1993).
Irradiation of Schistosoma mansoni
cercariae impairs neuromuscular function in developing schistosomula. J
Parasitol 79(2): 286-289.
A.P. Mountford and R.A. Wilson (1993).
Fractionation of schistosome
antigens by high performance electrophoretic chromatography and their
screening for the ability to induce Th1 lymphocyte activity. J Immunol
Methods 160(2): 237-244.
R.M. Pemberton, P.S. Coulson, L.E. Smythies and R.A. Wilson
(1993).
Phenotypic and functional properties of Th lines and clones recognizing
larval antigens of Schistosoma mansoni. Parasite Immunol 15(7):
373-382.
L.E. Smythies, P.S. Coulson and R.A. Wilson (1993).
Immunity to
Schistosoma mansoni in mice vaccinated with irradiated cercariae: cytokine
interactions in the pulmonary protective response. Ann Trop Med Parasitol
87(6): 653-657.
R.A. Wilson (1993).
Immunity and immunoregulation in helminth infections.
Curr Opin Immunol 5(4): 538-547.
R.A. Wilson and A. Sher (1993).
Vaccines against schistosomes: an
alternative view. Trans R Soc Trop Med Hyg 87(2): 237.
S.L. Constant and R.A. Wilson (1992).
In vivo lymphocyte responses in the
draining lymph nodes of mice exposed to Schistosoma mansoni: preferential
proliferation of T cells is central to the induction of protective immunity.
Cell Immunol 139(1): 145-161.
J.E. Crabtree, C.E. Pullar, L.K. Trejdosiewicz and R.A. Wilson
(1992).
Murine intestinal humoral responses in chronic Schistosoma mansoni infections. Scand J Immunol 35(3): 361-367.
A.P. Mountford, P.S. Coulson, R.M. Pemberton, L.E. Smythies
and R.A.
Wilson (1992).
The generation of interferon-gamma-producing T lymphocytes in
skin-draining lymph nodes, and their recruitment to the lungs, is associated
with protective immunity to Schistosoma mansoni. Immunology 75(2):
250-256.
E.C. Ratcliffe and R.A. Wilson (1992).
The role of mononuclear-cell
recruitment to the lungs in the development and expression of immunity to
Schistosoma mansoni. Parasitology 104 ( Pt 2): 299-307.
L.E. Smythies, P.S. Coulson and R.A. Wilson (1992).
Monoclonal antibody
to IFN-gamma modifies pulmonary inflammatory responses and abrogates
immunity to Schistosoma mansoni in mice vaccinated with attenuated
cercariae. J Immunol 149(11): 3654-3658.
L.E. Smythies, R.M. Pemberton, P.S. Coulson, A.P. Mountford
and R.A.
Wilson (1992).
T cell-derived cytokines associated with pulmonary immune
mechanisms in mice vaccinated with irradiated cercariae of Schistosoma
mansoni. J Immunol 148(5): 1512-1518.
L.M. Timothy, P.S. Coulson, J.M. Behnke and R.A. Wilson
(1992).
Cross-reactivity between Necator americanus and Schistosoma
mansoni
in mice.
Int J Parasitol 22(8): 1143-1149.
R.A. Wilson (1992).
T cell derived cytokines in lung-phase immunity to
Schistosoma mansoni. Mem Inst Oswaldo Cruz 87 Suppl 4:
105-109.
R.M. Pemberton, L.E. Smythies, A.P. Mountford and R.A. Wilson
(1991).
Patterns of cytokine production and proliferation by T lymphocytes differ in
mice vaccinated or infected with Schistosoma mansoni. Immunology
73(3): 327-333.
E.C. Ratcliffe and R.A. Wilson (1991).
The magnitude and kinetics of
delayed-type hypersensitivity responses in mice vaccinated with irradiated
cercariae of Schistosoma mansoni. Parasitology 103 Pt 1:
65-75.
S.L. Constant, A.P. Mountford and R.A. Wilson (1990).
Phenotypic analysis
of the cellular responses in regional lymphoid organs of mice vaccinated
against Schistosoma mansoni. Parasitology 101 Pt 1: 15-22.
T. Kambara and R.A. Wilson (1990).
In situ pulmonary responses of T cell
and macrophage subpopulations to a challenge infection in mice vaccinated
with irradiated cercariae of Schistosoma mansoni. J Parasitol 76(3):
365-372.
E.N. Menson and R.A. Wilson (1990).
Lung-phase immunity to Schistosoma
mansoni: definition of alveolar macrophage phenotypes after vaccination and
challenge of mice. Parasite Immunol 12(4): 353-366.
A.P. Mountford and R.A. Wilson (1990).
Schistosoma mansoni: the effect of
regional lymphadenectomy on the level of protection induced in mice by
radiation-attenuated cercariae. Exp Parasitol 71(4): 463-469.
R. Aitken and R.A. Wilson (1989).
The growth and development of
Schistosoma mansoni in mice exposed to sublethal doses of radiation. J
Parasitol 75(6): 958-963.
P.S. Coulson and A.P. Mountford (1989).
Fate of attenuated schistosomula
administered to mice by different routes, relative to the immunity induced
against Schistosoma mansoni. Parasitology 99 Pt 1: 39-45.
P.S. Coulson and R.A. Wilson (1989).
Portal shunting and resistance to
Schistosoma mansoni in 129 strain mice. Parasitology 99 Pt 3:
383-389.
E.N. Menson, P.S. Coulson and R.A. Wilson (1989).
Schistosoma mansoni:
circulating and pulmonary leucocyte responses related to the induction of
protective immunity in mice by irradiated parasites. Parasitology
98 ( Pt 1): 43-55.
E.N. Menson and R.A. Wilson (1989).
Lung-phase immunity to Schistosoma
mansoni. Flow cytometric analysis of macrophage activation states in
vaccinated mice. J Immunol 143(7): 2342-2348.
A.P. Mountford, P.S. Coulson, N. Saunders and R.A. Wilson
(1989).
Characteristics of protective immunity in mice induced by drug-attenuated
larvae of Schistosoma mansoni. Antigen localization and antibody responses.
J Immunol 143(3): 989-995.
S. Riengrojpitak, M. Vojvodic, C. Boot and R.A. Wilson (1989).
Reactivity
of anti-tegument monoclonal antibodies with target epitopes in different
worm tissues and developmental stages of Schistosoma mansoni.
Parasitology 98 Pt 2: 213-225.
R. Aitken, P.S. Coulson and R.A. Wilson (1988).
Pulmonary leukocytic
responses are linked to the acquired immunity of mice vaccinated with
irradiated cercariae of Schistosoma mansoni. J Immunol 140(10):
3573-3579.
P.S. Coulson and R.A. Wilson (1988).
Examination of the mechanisms of
pulmonary phase resistance to Schistosoma mansoni in vaccinated mice. Am
J Trop Med Hyg 38(3): 529-539.
A.N. MacGregor, J.R. Kusel and R.A. Wilson (1988).
Isolation and
characterisation of discoid granules from the tegument of adult Schistosoma
mansoni. Parasitol Res 74(3): 250-254.
A.P. Mountford, P.S. Coulson and R.A. Wilson (1988).
Antigen localization
and the induction of resistance in mice vaccinated with irradiated cercariae
of Schistosoma mansoni. Parasitology 97 ( Pt 1): 11-25.
S.M. Roberts, C. Boot and R.A. Wilson (1988). Antibody responses of
rodents to a tegument membrane preparation from adult Schistosoma mansoni.
Parasitology 97 ( Pt 3): 425-435.
N. Saunders, S.M. Roberts and R.A. Wilson (1988).
Diazotised
[125I]iodosulphanilic acid is not a marker for the outer bilayer of the
tegument of adult Schistosoma mansoni. Mol Biochem Parasitol 28(3):
217-226.
R. Aitken, P.S. Coulson, B. Dixon and R.A. Wilson (1987).
Radiation-resistant acquired immunity of vaccinated mice to Schistosoma
mansoni. Am J Trop Med Hyg 37(3): 570-577.
J.E. Crabtree and R.A. Wilson (1987).
Pulmonary cellular reactions to
Schistosoma mansoni schistosomula in normal and vaccinated mice. Adv Exp
Med Biol 216A: 701-707.
M.J. Ford, M.G. Taylor, S.M. McHugh, R.A. Wilson and D.L. Hughes (1987).
Studies on heterologous resistance between Schistosoma mansoni and Fasciola
hepatica in inbred rats. Parasitology 94 ( Pt 1): 55-67.
S.M. McHugh, P.S. Coulson and R.A. Wilson (1987).
The relationship
between pathology and resistance to reinfection with Schistosoma mansoni
in
mice: a causal mechanism of resistance in chronic infections.
Parasitology 94 ( Pt 1): 81-91.
S.M. McHugh, P.S. Coulson and R.A. Wilson (1987).
Pathologically induced
alterations in the dimensions of the hepatic portal vasculature of mice
infected with Schistosoma mansoni. Parasitology 94 ( Pt 1):
69-80.
S.M. Roberts, R.A. Wilson, J.H. Ouma, H.C. Kariuki, D. Koech, T.K. arap
Siongok, R.F. Sturrock and A.E. Butterworth (1987).
Immunity after treatment
of human schistosomiasis mansoni quantitative and qualitative antibody
responses to tegumental membrane antigens prepared from adult worms.
Trans R Soc Trop Med Hyg 81(5): 786-793.
N. Saunders, R.A. Wilson and P.S. Coulson (1987).
The outer bilayer of
the adult schistosome tegument surface has a low turnover rate in vitro
and
in vivo. Mol Biochem Parasitol 25(2): 123-131.
J.E. Crabtree and R.A. Wilson (1986).
The role of pulmonary cellular
reactions in the resistance of vaccinated mice to Schistosoma mansoni.
Parasite Immunol 8(3): 265-285.
J.E. Crabtree and R.A. Wilson (1986).
Schistosoma mansoni: an ultrastructural examination of pulmonary migration. Parasitology
92 ( Pt 2): 343-354.
J.E. Crabtree and R.A. Wilson (1986).
Techniques for locating isotopically labelled schistosomula of Schistosoma mansoni in host tissues
for ultrastructural investigations. J Helminthol 60(1): 75-78.
B.L. Mangold, D.A. Dean, P.S. Coulson and R.A. Wilson (1986).
Site
requirements and kinetics of immune-dependent elimination of intravascularly
administered lung stage schistosomula in mice immunized with highly
irradiated cercariae of Schistosoma mansoni. Am J Trop Med Hyg 35(2):
332-344.
R.A. Wilson and P.S. Coulson (1986).
Schistosoma mansoni: dynamics of
migration through the vascular system of the mouse. Parasitology
92 ( Pt 1): 83-100.
R.A. Wilson, P.S. Coulson and B. Dixon (1986).
Migration of the schistosomula of Schistosoma mansoni in mice vaccinated with
radiation-attenuated cercariae, and normal mice: an attempt to identify the
timing and site of parasite death. Parasitology 92 (Pt 1):
101-116.
J.E. Crabtree and R.A. Wilson (1985).
Schistosoma mansoni: an ultrastructural examination of skin migration in the hamster cheek pouch.
Parasitology 91 ( Pt 1): 111-120.
A. Mastin, Q.D. Bickle and R.A. Wilson (1985).
An ultrastructural
examination of irradiated, immunizing schistosomula of Schistosoma mansoni
during their extended stay in the lungs. Parasitology 91 ( Pt 1):
101-110.
A.J. Mastin, R.A. Wilson and Q.D. Bickle (1985).
Induction of resistance
to Schistosoma mansoni in mice by chemotherapy: migration of schistosomula
in primary and challenge infections. Parasitology 90 ( Pt 3):
519-528.
J.E. Crabtree and R.A. Wilson (1984).
Schistosoma mansoni: cellular
reactions to challenge infections in the cheek pouch skin of chronically
infected Chinese hamsters. Parasitology 89 ( Pt 1): 59-69.
R.A. Wilson and P.S. Coulson (1984).
The effect of soft-wood sawdust
bedding on the maturation of an infection of Schistosoma mansoni in mice
exposed to cercariae via the tail or abdominal skin. Trans R Soc Trop Med
Hyg 78(3): 411-412.
J.R. Lawson and R.A. Wilson (1983).
The relationship between the age of
Schistosoma mansoni cercariae and their ability to penetrate and infect the
mammalian host. Parasitology 87 (Pt 3): 481-492.
A.J. Mastin, Q.D. Bickle and R.A. Wilson (1983).
Schistosoma mansoni:
migration and attrition of irradiated and challenge schistosomula in the
mouse. Parasitology 87 (Pt 1): 87-102.
S.M. Roberts, R. Aitken, M. Vojvodic, E. Wells and R.A. Wilson
(1983).
Identification of exposed components on the surface of adult Schistosoma
mansoni by lactoperoxidase-catalysed iodination. Mol Biochem Parasitol
9(2): 129-143.
S.M. Roberts, A.N. MacGregor, M. Vojvodic, E. Wells, J.E. Crabtree
and R.A. Wilson (1983).
Tegument surface membranes of adult Schistosoma mansoni:
development of a method for their isolation. Mol Biochem Parasitol
9(2): 105-127.
R.A. Wilson, P.S. Coulson and S.M. McHugh (1983).
A significant part of
the 'concomitant immunity' of mice to Schistosoma mansoni is the consequence
of a leaky hepatic portal system, not immune killing. Parasite Immunol
5(6): 595-601.
R.M. Anderson, J.G. Mercer, R.A. Wilson and N.P. Carter (1982).
Transmission of Schistosoma mansoni from man to snail: experimental studies
of miracidial survival and infectivity in relation to larval age, water
temperature, host size and host age. Parasitology 85 (Pt 2):
339-360.
N.P. Carter, R.M. Anderson and R.A. Wilson (1982).
Transmission of
Schistosoma mansoni from man to snail: laboratory studies on the influence
of snail and miracidial densities on transmission success. Parasitology
85 (Pt 2): 361-372.
J.E. Crabtree and R.A. Wilson (1980).
Schistosoma mansoni: a scanning
electron microscope study of the developing schistosomulum. Parasitology
81(Pt 3): 553-564.
J.R. Lawson and R.A. Wilson (1980).
The survival of the cercariae of
Schistosoma mansoni in relation to water temperature and glycogen
utilization. Parasitology 81(2): 337-348.
J.R. Lawson and R.A. Wilson (1980).
Metabolic changes associated with the
migration of the schistosomulum of Schistosoma mansoni in the mammal host.
Parasitology 81(2): 325-336.
P. Miller and R.A. Wilson (1980).
Migration of the schistosomula of
Schistosoma mansoni from the lungs to the hepatic portal system.
Parasitology 80(2): 267-288.
R.A. Wilson and J.R. Lawson (1980).
An examination of the skin phase of
schistosome migration using a hamster cheek pouch preparation.
Parasitology 80(2): 257-266.
P.R. Wheater and R.A. Wilson (1979).
Schistosoma mansoni: a histological
study of migration in the laboratory mouse. Parasitology 79(1):
49-62.
R.A. Wilson and P.E. Barnes (1979).
Synthesis of macromolecules by the
epithelial surfaces of Schistosoma mansoni: an autoradiographic study.
Parasitology 78(3): 295-310.
P. Miller and R.A. Wilson (1978).
Migration of the schistosomula of
Schistosoma mansoni from skin to lungs. Parasitology 77(3):
281-302.
R.A. Wilson, T. Draskau, P. Miller and J.R. Lawson (1978).
Schistosoma
mansoni: the activity and development of the schistosomulum during migration
from the skin to the hepatic portal system. Parasitology 77(1):
57-73.
R.A. Wilson and P.E. Barnes (1977).
The formation and turnover of the membranocalyx on the tegument of Schistosoma mansoni. Parasitology
74(1): 61-71.
P.R. Wheater and R.A. Wilson (1976).
The tegument of Schistosoma mansoni:
a histochemical investigation. Parasitology 72(1): 99-109.
R.A. Wilson and P.E. Barnes (1974).
An
in vitro investigation of dynamic
processes occurring in the schistosome tegument, using compounds known to
disrupt secretory processes. Parasitology 68(2): 259-270.
R.A. Wilson and P.E. Barnes (1974).
The tegument of Schistosoma mansoni:
observations on the formation, structure and composition of cytoplasmic
inclusions in relation to tegument function. Parasitology 68(2):
239-258.
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