Professor David K. Smith Publications

2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001

2012

  • Self-Assembled Multivalency - Dynamic Ligand Arrays for HIgh-Affinity Binding.
    A Barnard, D K Smith, Angew Chem Int Ed, 2012, in press.
  • Exploring Molecular Recognition Pathways in One- and Two-Component Gels Formed by Dendritic Lysine-Based Gelators.
    J G Hardy, A R Hirst, D K Smith, Soft Matter, 2012, DOI:10.1039/C2SM25129A.
  • Cation-Selective Silver-Responsive Organogel - Exploiting Silver-Alkene Interactions in the Gel-Phase.
    W Edwards, D K Smith, Chem Commun, 2012, DOI 10.1039/c2cc17854k.
  • Probing Dendron Structure and Nanoscale Self-Assembly Using Computer-Aided Analysis of EPR Spectra.
    M F Ottaviani, M Cangiotti, L Fiorani, A Barnard, S P Jones, D K Smith, New J Chem, 2012, 39, 469-476.
  • Self-Assembling Fibrillar Networks - Supramolecular Gels.
    D K Smith, in "Supramolecular Chemistry: From Molecules to Nanomaterials", ed. P A Gale and J W Steed, Wiley-VCH, Weinheim, 2012
  • Soft Matter Science - A Supramolecular Perspective.
    D K Smith, in "Supramolecular Chemistry: From Molecules to Nanomaterials", ed. P A Gale and J W Steed, Wiley-VCH, Weinheim, 2012.

2011

  • Fluorescent 'Two-Faced' Polymer Wafers with Embedded Pyrene-Functionalised Gelator Nanofibres.
    J R Moffat, D K Smith, Chem Commun, 2011, 47, 11864-11866.
  • Controlled Release of DNA from Photoresponsive Hyperbranched Polyglycerols with Oligoamine Shells.
    W FIscher, A Barnard, M A Quadir, D K Smith, R Haag, Macromol Bioscience, 2011, 11, 1736-1746.
  • Comparing Dendritic and Self-Assembly Strategies to Multivalency - RGD Peptide-Integrin Interactions.
    D J Welsh and D K Smith, Org Biomol Chem, 2011, 9, 4795-4801.
  • Chemical Education - From Crazy Chemists to Engaged Learners.
    D K Smith, Nature Chem, 2011, 3, 681-684.
  • Self-Assembling Ligands for Nanoscale Multivalent Heparin Binding.
    A C Rodrigo, A Barnard, J Cooper and D K Smith, Angew Chem Int Ed, 2011, 50, 4675-4679.
  • Self-Sorting Multi-Gelator Gels - Mixing and Ageing Effects in Thermally Addressable Supramolecular Soft Nanomaterials.
    M M Smith and D K Smith, Soft Matter, 2011, 7, 4856-4860.
  • Hydrophobically Modified DNA Binding Dendrons – Developing Structure-Activity Relationships for DNA Binding and Gene Transfection.
    S P Jones, N P Gabrielson, C-H Wong, H-F Chow, D W Pack, P Posocco, M Fermeglia, S Pricl and D K Smith, Mol Pharm, 2011, 8, 416-429.
  • Synthetically Accessible, Tunable, Low-Molecular-Weight Oligopeptide Organogelators.
    C Lagadec and D K Smith, Chem Commun, 2011, 47, 340-342.
  • Solvent-Gelator Interactions - Using Empirical Solvent Parameters to Better Understand the Self-Assembly of Gel-Phase Materials.
    W Edwards, C Lagadec and D K Smith, Soft Matter, 2011, 7, 110-117.
  • Degradable Self-Assembling Dendrons for Gene Delivery – Experimental and Theoretical Insights into the Barriers to Cellular Uptake.
    A. Barnard, P. Posocco, S. Pricl, M. Calderon, R. Haag, M.E. Hwang, V.T. Shum, D.W. Pack, D.K. Smith, J Am Chem Soc, 2012, 133, 20288-2030.

2010

  • Quantifying the Effect of Surface Ligands on Dendron-DNA Interactions - Insights into Multivalence through a Combined Experimental and Theoretical Approach.
    S P Jones, G M Pavan, A Danani, S Pricl and D K Smith, Chem Eur J, 2010, 16, 4519-4532.
  • Supramolecular Gels - Building Bridges.
    D K Smith, Nature Chem, 2010, 2, 162-163.
  • Highly Tunable Modular Dendrons for DNA Binding and Delivery.
    D K Smith, PMSE Preprints, 2010.
  • Less is More - Multiscale Modelling of Self-Assembling Multivalency and its Impact on DNA Binding and Gene Delivery.
    P Posocco, S Pricl, S P Jones, A Barnard and D K Smith, Chem Sci, 2010, 1, 393-404.
  • Hierarchical Assembly - Dynamic Gel-Nanoparticle Hybrid Soft Materials Based on Biologically Derived Building Blocks.
    I A Coates and D K Smith, J Mater Chem, 2010, 20, 6696-6702.

2009

  • Controlled Self-Assembly - Synthetic Tunability and Covalent Capture of Nanoscale Gel Morphologies.
    I A Coates and D K Smith, Chem Eur J, 2009, 15, 6340-6344.
  • Encapsulated Binding Sites - Synthetically Simple Receptors for the Binding and Transport of HCl.
    K J Winstanley, S J Allen and D K Smith, Chem Commun, 2009, 4299-4301.
  • Modeling the Multivalent Recognition between Dendritic Molecules and DNA: Understanding How Ligand 'Sacrifice' and Screening Can Enhance Binding.
    G M Pavan, A Danani, S Pricl and D K Smith, J Am Chem Soc, 2009, 131, 9686-9694.
  • Nanocomposite Hydrogels - Controlled Synthesis of Chiral Polyaniline Nanofibers and their Inclusion in Agarose.
    X Zhang, V Chechik, D K Smith, P H Walton, A-K Duhme Klair and Y Luo, Synth Metals, 2009, 159, 2135-2140.
  • 'On-Off' Multivalent Recognition - Degradable Dendrons for Temporary High-Affinity DNA Binding.
    D J Welsh, S P Jones and D K Smith, Angew Chem Int Ed, 2009, 48, 4047-4051.
  • Metathesis within Self-Assembled Gels - Transcribing Nanostructured Soft Materials into a More Robust Form.
    J R Moffat, I A Coates, F J Leng and D K Smith, Langmuir, 2009, 25, 8786-8793.
  • Self-assembly of two-component gels: Stoichiometric control and component selection.
    A R Hirst, J F Miravet, B Escuder, L Noirez, V Castelletto, I W Hamley and D K Smith, Chem Eur J, 2009, 15, 372-279.
  • Controlled self-sorting in the assembly of 'multi-gelator' gels.
    J R Moffat and D K Smith, Chem Commun, 2009, 316-318.
  • Synergistic effects on gene delivery - Co-formulation of small disulfide-linked dendritic polycations with lipofectamine 2000.
    J G Hardy, C S Love, N P Gabrielson, D W Pack and D K Smith, Org Biomol Chem, 2009, 7, 789-793.
  • Lost in translation: Chirality effects in the self-assembly of nanostructured gel-phase materials.
    D K Smith, Chem Soc Rev, 2009, 38, 684-694.

2008

  • High-molecular-weight polymers for protein crystallisation: poly-gamma-glutamic acid-based precipitants.
    T-C Hu, J Korczynska, D K Smith and M Brzozowski, Acta Crystallogr D: Biol Crystallogr, 2008, 64, 957-963.
  • Synergistic effects in gene delivery – A structure-activity approach to the optimisation of hybrid dendritic-lipidic transfection agents.
    S P Jones, N P Gabrielson, D W Pack and D K Smith, Chem Commun, 2008, 4700-4702.
  • Nanostructured polymers with embedded self-assembled reactive gel networks.
    J R Moffat, G J Seeley, J T Carter, A Burgess, D K Smith, Chem Commun, 2008, 4601-4603.
  • Low Molecular Weight Gelators - Elucidating the Principles of Gelation Based on Gelator Solubility and a Cooperative Binding Model.
    A R Hirst, I A Coates, T Boucheteau, J F Miravet, B Escuder, V Castelletto, I W Hamley and D K Smith, J Am Chem Soc, 2008, 130, 9113-9121.
  • Molecular Gels - Nanostructured Soft Materials.
    D K Smith in "Organic Nanostructures",ed. J W Steed and J L Atwood, Wiley-VCH, Weinheim, 2008.
  • Metastable two-component gel - Exploring the gel-crystal interface.
    J R Moffat and D K Smith, Chem Commun, 2008, 2248-2250.
  • Controlled Synthesis of Optically Active Polyaniline Nanorods and Nanostructured Gold Microspheres using Tetrachloroaurate as Efficient Oxidant.of Aniline.
    X Zhang, V Chechik, D K Smith, P H Walton and A-K Duhme-Klair, Macromolecules, 2008, 41, 3417-3421.
  • High-Tech Applications of Self-Assembling Supramolecular Nanostructured Gel-Phase Materials - From Regenerative Medicine to Electronic Devices.
    A R Hirst, B Escuder, J-F Miravet and D K Smith, Angew Chem Int Ed, 2008, 47, 8002-8018.
  • Dendrimers and the Double Helix - From DNA Binding to Gene Therapy.
    D K Smith, Curr Top Med Chem, 2008, 8, 1187-1203.
  • From Nanochemistry to Nanomedicine - Delivering New Drugs.
    D K Smith, Educ Chem, 2008, 45, 113-116.

2007

  • Modular construction and hierarchical gelation of organooxotin nanoclusters derived from simple building blocks.
    U Hahn, A R Hirst, J L Delgado, A Kaeser, B Delavaux-Nicot, J-F Nierengarten and D K Smith, Chem. Commun., 2007, 4943-4945.
  • Precisely defined protein-polymer conjugates: Construction of synthetic DNA binding domains on proteins by using multivalent dendrons.
    M A Kostiainen, G R Szilvay, J Lehtinen, D K Smith, M B Linder, A Urtti and I Ikkala, ACS Nano, 2007, 1, 103-113
  • Optically triggered release of DNA from multivalent dendrons by switching-off multivalency.
    M A Kostiainen, D K Smith and O Ikkala, Angew Chem Int Ed, 2007, 46, 7600-7604.
  • Synthetically accessible, high affinity phosphate anion receptors.
    H F M Nelissen and D K Smith, Chem Commun, 2007, 3039-3041.
  • Self-organisation in the assembly of gels from mixtures of different dendritic peptide building blocks.
    A R Hirst, B. Huang, V. Castelletto, I. W. Hamley and D. K. Smith, Chem Eur J, 2007, 13, 2180-2188.
  • Ortho-substituted catechol derivatives: The effect of intramolecular hydrogen-bonding pathways on chloride anion recognition.
    K J Winstanley and D K Smith, J Org Chem, 2007, 72, 2803-2815.
  • Dendritic nanoparticles – The impact of ligand cross-linking on nanocore stability.
    C S Love, I Ashworth, C Brennan, V Chechik and D K Smith, Langmuir, 2007, 23, 5787-5794.
  • Optimizing biomimetic gelators constructed from amino acid building blocks.
    I A Coates, A R Hirst and D K Smith, J Org Chem, 2007, 72, 3937-3940.
  • Exploring molecular recognition pathways within a family of gelators with different hydrogen bonding motifs.
    J G Hardy, A R Hirst, I Ashworth, C Brennan and D K Smith, Tetrahedron, 2007, 63, 7397-7406.
  • Molecular gels – Underpinning nanoscale materials with organic chemistry.
    D K Smith, Tetrahedron, 2007, 63, 7283-7284.
  • Dendritic receptors designed to bind polyanions in both organic and aqueous media.
    J G Hardy, I Ashworth, C Brennan and D K Smith, Org Biomol Chem, 2007, 5, 900-906.
  • Crown ether functionalised dendrons – Controlled binding and release of dopamine in both solution and gel phases.
    S V Brignell and D K Smith, New J Chem, 2007, 31, 1243-1249.
  • Microscale vapour diffusion for protein crystallisation.
    J Korczynska, T-C Hu, D K Smith, J Jenkins, R Lewis, T Edwards and A M Brzozowski, Acta Crystallogr D: Biol Crystallogr, 2007, 63, 1009-1015.

2006

  • Multivalent dendrons for high affinity adhesion of proteins to DNA.
    M A Kostiainen, G R Szilvay, D K Smith, M B Linder and O Ikkala, Angew Chem Int Ed, 2006, 45, 3538-3542.
  • Dendrons with spermine surface groups as potential non-viral vectors for use in gene therapy.
    J G Hardy, M Kostiainen, D K Smith, N P Gabrielson and D W Pack, Bioconjugate Chem, 2006, 17, 172-178.
  • Supramolecular dendrimer chemistry - Towards controllable nanomaterials.
    D K Smith, Chem Commun, 2006, 34-44.
  • Dendritic gels - Many arms make light work.
    D K Smith, Adv Mater, 2006, 18, 2773-2778.
  • Dendritic nanoparticles - Effect of dendritic structure on nanoparticle size and chemical stability.
    C S Love, I Ashworth, C Brennan, V Chechik and D K Smith, J Coll Interface Sci, 2006, 302, 178-186.
  • Anion binding by catechols - an NMR, optical and electrochemical study.
    K J Winstanley, A M Sayer and D K Smith, Org Biomol Chem, 2006, 4, 1760-1767.
  • The mid-lecture break - An overview and some new approaches
    D K Smith, J Chem Educ, 2006, 83, 1621-1624.
  • Branching Out.
    D K Smith, Chem Ind, 2006, Nov 6, 30-31.
  • Nanochemistry - Delivering new medicines?
    D K Smith, Chemistry Review, 2006, 16, 6-10.

2005

  • Unique nanoscale morphologies underpinning organic gel-phase materials.
    A R Hirst, D K Smith and J P Harrington, Chem Eur J, 2005, 11, 6552-6559.
  • Robust gels created using a self-assembly and covalent capture strategy.
    C S Love, V Chechik, D K Smith, I Ashworth and C Brennan, Chem Commun, 2005, 5647-5649.
  • Dendritic gelators.
    A R Hirst and D K Smith, Top Curr Chem, 2005, 256, 237-273.
  • Two-component gel-phase materials - highly tunable self-assembling systems.
    A R Hirst and D K Smith, Chem Eur J, 2005, 11, 5496-5508.
  • High-affinity multivalent DNA binding by using low-molecular-weight dendrons.
    M A Kostiainen, J G Hardy and D K Smith, Angew Chem Int Ed, 2005, 44, 2556-2559.
  • Self-assembly using dendritic building blocks - towards controllable nanomaterials.
    D K Smith, A R Hirst, C S Love, J G Hardy, S V Brignel and B Huang, Prog Polym Sci, 2005, 30, 220-293.
  • A Direct Comparison of One- and Two-Component Dendritic Self-Assembled Materials: Elucidating Molecular Recognition Pathways.
    B Huang, A R Hirst, D K Smith, V Castelletto and I W Hamley, J Am Chem Soc, 2005, 127, 7130-7139.
  • Synthesis of gold nanoparticles within a supramolecular gel-phase network.
    C S Love, V Chechik, D K Smith, K Wilson, I Ashworth and C Brennan, Chem Commun, 2005, 1971-1973.
  • A supramolecular approach to medicinal chemistry: Medicine beyond the molecule.
    D K Smith, J Chem Educ, 2005, 82, 393-400.
  • Controlling the materials properties and nanostructure of a single-component dendritic gel by adding a second component.
    J G Hardy, A R Hirst, D K Smith, C Brennan and I Ashworth, Chem Commun, 2005, 385-387.
  • A direct comparison of one- and two-component dendritic self-assembled materials: elucidating molecular recognition pathways.
    B Huang, A R Hirst, D K Smith, V Castelletto and I W Hamley, J Am Chem Soc, 2005, 127, 7130-7139.
  • Synthetic Phosphate Receptor.
    H F M Neliseen and D K Smith, UK Patent P110446WO.

2004

  • Two component dendritic gel: Effect of stereochemistry on the supramolecular chiral assembly.
    A R Hirst, D K Smith, M C Feiters and H P M Geurts, Chem Eur J, 2004, 10, 5901-5902.
  • Solvent effects on supramolecular gel-phase materials: Two-component dendritic gel.
    A R Hirst and D K Smith, Langmuir, 2004, 20, 10851-10857.
  • Two component dendritic gel: Effect of spacer chain length on the supramolecular chiral assembly.
    A R Hirst, D K Smith, M C Feiters and H P M Geurts, Langmuir, 2004, 20, 7070-7077.
  • One component gel based on peptidic dendrimers: Dendritic effects on materials properties.
    C S Love, A R Hirst, V Chechik, D K Smith, I Ashworth and C Brennan, Langmuir, 2004, 20, 6580-6585.
  • Self-assembly of two component peptidic dendrimers: Dendritic effects on materials properties.
    A R Hirst and D K Smith, Org Biomol Chem, 2004, 2, 2965-2971.
  • NMR and ESR investigations of the interaction between a carboxylic acid and an amine at the focal point of L-lysine based dendritic branches.
    G M Dykes, D K Smith and A Caragheoropol, Org Biomol Chem, 2004, 2, 922-926.
  • Dendron-stabilised gold nanoparticles: Generation dependence of core size and thermal stability.
    C S Love, V Chechik, D K Smith and C Brennan, J Mater Chem, 2004, 14, 919-923.
  • Copper amino-acid complexes with encapsulated metal centres.
    D L Stone, D K Smith and A C Whitwood, Polyhedron, 2004, 23, 1709-1717.
  • Chiral dendrimers with biomedical applications.
    D K Smith, Speciality Chemicals Magazine, 2004, 24. 42-43.

2003

  • Rapid screening of binding constants by calibrated competitive 1H NMR.
    R E Heath, Dykes G M, H Fish and D K Smith, Chem Eur J, 2003, 9, 850-855.
  • Anion binding at the core of branched ferrocene derivatives.
    D L Stone and D K Smith, Polyhedron, 2003, 22, 763-768.
  • Recent developments in dendrimer chemistry – An introduction.
    D K Smith, Tetrahedron, 2003, 59, 3797-798.
  • Supramolecular dendrimer chemistry: Using dendritic crown ethers to reversibly generate functional assemblies.
    G M Dykes and D K Smith, Tetrahedron, 2003, 59, 3999-4009. 
  • Syntheses of dendritic branches based on L-lysine – Is the stereochemical information preserved throughout the synthesis?
    M Driffield M, D M Goodall, A S Klute and D K Smith, Org Biomol Chem, 2003, 1, 2612-2620.
  • Two component dendritic gels: Easily tunable materials.
    A R Hirst, D K Smith, M C Feiters, H P M Geurts and A C Wright, J Am Chem Soc, 2003, 125, 9010-9011.
  • Dendritic lanthanide complexes: The effect of Lewis acid encapsulation.
    D L Stone, G M Dykes and D K Smith, Dalton Trans, 2003, 3902-3906.
  • Rapid NMR screening of chloride receptors: Uncovering catechol as a useful anion binding motif.
    D K Smith, Org Biomol Chem, 2003, 1, 3874-3877.
  • Molecular recognition using dendritic building blocks – Towards controllable nanomaterials.
    D K Smith, Polymer Preprints (ACS meeting, New York, 2003), 2003, 44, 487-488.
  • To molecules and beyond.
    D K Smith, Educ Chem, 2003, 40, 67-69 and 77.
  • Sense and sensor ability.
    D K Smith., Chemistry Review, 2003, 13, 2-5.

2002

  • Ferrocene encapsulated within symmetric dendrimers:
    a deeper understanding of dendritic effects on redox potential    .
    D L Stone, D K Smith and P T McGrail, J Am Chem Soc, 2002, 124, 856-864.
  • Synthesis and characterization of silica-supported L-lysine based dendritic branches.
    M Driffield, D M Goodall, A S Klute, D K Smith and K Wilson, Langmuir, 2002, 18, 8660-8665.
  • Controlled release of a dendritically encapsulated template molecule.
    G M Dykes, D K Smith and G J Seeley, Angew Chem Int Ed, 2002, 41, 3254-3257.

2001

  • Supramolecular solubilisation of hydrophilic dyes using individual dendritic branches.
    G M Dykes, L J Brierley, D K Smith and P T McGrail, Chem Eur J, 2001, 7, 4730-4739. 
  • A dendritic active site: Diastereoselective catalysis of the nitroaldol reaction.
    A V Davis, M Driffield and D K Smith, Org Lett, 2001, 3, 3075-3078. 
  • Supramolecular two-component dendritic gel.
    K S Partridge, D K Smith, G M Dykes and P T McGrail, Chem Commun, 2001, 319-320.
  • Dendritic biomimicry: Microenvironmental hydrogen bonding effects on tryptophan fluorescence.
    S Koenig, L Müller and D K Smith, Chem Eur J, 2001, 7, 979-986.
  • High performance liquid chromatography applications of OR detection with compensation for scattering and absorbance at the laser wavelength.
    M Driffield, E T Bergstrom, D M Goodall, A S Prangle and D K Smith, J Chrom A, 2001, 939, 41-48.
  • New dawn for chemistry
    D K Smith, Chem Ind, 2001, 247-248.
 
David Smith

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