Professor Ian Fairlamb Recent Publications

 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001

2012

  • On the appearance of nitrite anion in [PdX(OAc)L2] and [Pd(X)(C^N)L] syntheses (X = OAc or NO2): photocrystallographic identification of metastable Pd(η1-ONO)(C^N)PPh3
    S E Bajwa, T E Storr, L E Hatcher, T J Williams, C G Baumann, A C Whitwood, D R Allan, S J Teat, P R Raithby and I J S Fairlamb, Chemical Science, 2012, in press.

2011

  • Synthesis and characterization of imine-palladacycles containing imidate ‘pseudohalide’ ligands: efficient Suzuki-Miyaura cross-coupling precatalysts and their activation to give Pd0Ln species (L = phosphine)
    J L Serrano, L García, J Pérez, E Pérez, J García, G Sánchez, P Sehnal, S De Ornellas, T J Williams and I J S Fairlamb, Organometallics 2011, 30, 5095-5109.
  • Synthesis and reactivity of molybdenum complexes containing functionalized alkynyl ligands: A photochemically-activated CO-releasing molecule (Photo-CO-RM)
    W-Q Zhang, A J Aktin, I J S Fairlamb, A C Whitwood and J M Lynam, Organometallics 2011, 30, 4643-4654.
  • Regiochemistry in Cobalt-mediated intermolecular Pauson-Khand reactions of unsymmetrical internal heteroaromatic alkynes with norbornene
    B E Moulton, A C Whitwood, A K Duhme-Klair, J M Lynam and I J S Fairlamb, J. Org. Chem. 2011, 76, 5320-5334.
  • Modification of the deoxy-myoglobin/carbonmonoxy-myoglobin UV-vis assay for reliable determination of CO-release rates from organometallic carbonyl complexes
    A J Atkin, J M Lynam, B E Moulton, P Sawle, R Motterlini, N M Boyle, M T Pryce and I J S Fairlamb, Dalton Trans. 2011, 40, 5755-5761.
  • Dalton Discussion 12: Catalytic C--H and C--X Bond Activation
    I J S Fairlamb, Platinum Metals Review, 2011, 55, 82-88.  
  • Direct C-H/C-X coupling methodologies mediated by Pd/Cu or Cu: an examination of the synthetic applications and mechanistic findings
    S De Ornellas, T E Storr, T J Williams, C G Baumann and I J S Fairlamb, Curr. Org. Synth. (invited contribution for special issue on C-X and C-H activation), 2011, 8, 79-101.
  • Cu(I) complexes containing a multidentate and conformationally flexible dibenzylidene acetone ligand (dbathiophos): application in catalytic alkene cyclopropanation
    A G Jarvis, A C Whitwood and I J S Fairlamb, Dalton Trans., 2011, 40, 3695-3702.
  • Interrogation of a Sonogashira cross-coupling of 8-bromoguanosine with phenylacetylene on Amberlite: Evidence for Pd/Cu ion binding and propagation of Pd/Cu nanoparticles
    A G Firth, K Wilson, C G Baumann and I J S Fairlamb, Nucleosides, Nucleotides and Nucleic acids, 2011, 30, 168-184.
  • The influence of alkenes as π-acidic ligands in Pd-catalysed cross-couplings
    A G Jarvis and I J S Fairlamb, Curr. Org. Chem. (invited contribution for special issue 'New trends in palladium chemistry: synthesis, structure, reactivity and applications'), 2011, 22, 3175-3196.

2010

  • Dalton Discussion 12: Catalytic C–H and C–X bond activation (DD12)
    T B Marder, P W Dyer, I J S Fairlamb, S Gibson and P Scott, Dalton Trans. 2010, 39, 10335-10337.
  • Atropisomerisation in sterically hindered alpha,beta-disubstituted cyclopentenones derived from an intermolecular cobalt(0)-mediated Pauson-Khand reaction
    B E Moulton, J M Lynam, A K Duhme-Klair, W Zheng, Z. Lin and I J S Fairlamb, Org Biomol Chem, 2010, 8, 5398.
  • A sequential direct arylation/Suzuki-Miyaura cross-coupling transformation of unprotected 2'-deoxyadenosine affords a novel class of fluorescent analogues
    T E Storr, J A Strohmeier, C G Baumann and I J S Fairlamb, Chem Commun, 2010, 46, 6470-6472.
  • Group 6 Carbon Monoxide-Releasing Metal Complexes with Biologically-Compatible Leaving Groups
    W Zhang, A C Whitwood, I J S Fairlamb, J M Lynam, Inorg Chem, 2010, 49, 8941-8952.
  • Highly regio- and chemoselective palladium(0)-mediated allylic substitution of difunctional allylic halides with phenols
    A R Kapdi, R J K Taylor and I J S Fairlamb, Tetrahedron Lett, 2010, 51, 6378-6380.
  • Surface catalysed Suzuki-Miyaura cross-coupling by Pd nanoparticles: an operando XAS study
    A F Lee, P J Ellis, I J S Fairlamb and K Wilson, Dalton Discussion 12, Dalton Trans., 2010, 39, 10473-10482.
  • Pd-catalysed regioselective C-H functionalisation of 2-pyrones
    M J Burns, R J Thatcher, R J K Taylor and I J S Fairlamb, Dalton Discussion 12, Dalton Trans., 2010, 39, 10391-10400.
  • Organometallic Chemistry.
    I J S Fairlamb and J M Lynam (Editors), in Organometallic Chemistry, RSC book publishing, 2010, 36, 1-182.
  • The emergence of palladium(IV) chemistry in synthesis and catalysis
    P Sehnal, R J K Taylor, I J S Fairlamb, Chem Rev 2010, 110, 824-889 (special issue on C-H functionalization; Guest Ed. R H Crabtree).
  • Remarkable anion effects uncovered in the development of a Au(III)-catalyzed tandem nucleophillic substitution-1,5-enyne cycloisomerization process
    J P Reeds, A C Whitwood, M P Healy, I J S Fairlamb , Chem Commun 2010, 46, 2046–2048.
  • Evidence for the Surface Catalysed Suzuki-Miyaura Reaction over Pd Nanoparticles: an Operando XAS Study
    P J Ellis, I J S Fairlamb S F J Hackett, K Wilson and A F Lee, Angew Chem Int Ed 2010, 49, 1820-1824.

2009

  • The phosphine-catalyzed Wittig reaction: a new vista for olefin synthesis?
    I J S Fairlamb, ChemSusChem, 2009, 2, 1021-1024.
  • Ion-tagged π-acidic alkene ligands promote Pd-catalysed allyl-aryl couplings in an ionic liquid.
    P S Bäuerlein, I J S Fairlamb, A G Jarvis, A F Lee, C Müller, J M Slattery, R J Thatcher, D Vogt and A C Whitwood, Chem Commun, 2009, 5734-5736.
  • Pd(0)/Cu(I)-Mediated direct arylation of 2'-deoxyadenosines: mechanistic role of Cu(I) and reactivity comparisons with related purine nucleosides.
    T E Storr, C G Baumann, R J Thatcher, S De Ornellas, A C Whitwood and I J S Fairlamb, J Org Chem, 2009, 74, 5810-5821.
  • N-Heterocyclic carbene coated metal nanoparticles.
    E C Hurst, I J S Fairlamb and V. Chechik, New J Chem 2009, 33, 1837-1840.
  • Interrogation of a dynamic multi-catalyst ensemble in asymmetric catalysis.
    J Eastoe, I J S Fairlamb, J M Fernández-Hernández, E Filali, J C Jeffery, G C Lloyd-Jones, A Martorell, A Meadowcroft, P-O Norrby, T Riis-Johannessen, D A Sale and P M Tomlin, Faraday Discussion 2009, in press (from post-doctoral studies).
  • Palladium-catalysed cross-coupling and related processes: some interesting observations that have been exploited in synthetic chemistry.
    G P McGlacken and I J S Fairlamb, Eur J Org Chem 2009, 4011-4029.
  • Organometallic Chemistry.
    I J S Fairlamb and J M Lynam (Editors), in Organometallic Chemistry, RSC book publishing, 2009, 35, 1-259.
  • 2-Alkyne dicobalt(0)hexacarbonyl complexes as carbon monoxide-releasing molecules (CO-RMs): probing the release mechanism.
    A J Atkin, S Williams, P Sawle, R Motterlini, J M Lynam and I J S Fairlamb, Dalton Trans, 2009, 3653–3656.
  • Suzuki-Miyaura cross-couplings mediated by trans-PdBr(N-Succ)(PPh3)2: a convenient synthetic method for diaryl- and aryl(heteroaryl)methanes.
    I J S Fairlamb, P Sehnal and R J K Taylor, Synthesis, 2009, 508-510.
  • Heteroaromatic analogues of dibenzylideneacetone (dba) and Pd0 2(het-dba)3 complexes: effect of a thienyl moiety on the reactivity of Pd02-thn-dba)(PPh3)2/Pd0(PPh3)2 and Pd02-th2-dba)(dppe)/Pd0(dppp) in oxidative addition reactions with iodobenzene.
    P Sehnal, H Taghzouti, I J S Fairlamb, A Jutand, A F Lee and A C Whitwood, Organometallics, 2009, 28, 824-829.
  • Diversity and design of metal-based carbon monoxide-releasing molecules (CO-RMs) in aqueous systems: revealing the essential trends.
    W-Q Zhang, A J Atkin, A C Whitwood, I J S Fairlamb and J M Lynam, Dalton Trans, 2009, 4351-4358 (special issue on Bioorganometallic Chemistry).

2008

  • A natural light induced regioselective 6π-electrocyclisation / oxidative aromatisation reaction: Experimental and theoretical insights.
    B E Moulton, H Dong, C T O’Brien, S B Duckett, Z Lin and I J S Fairlamb, Org Biomol Chem, 2008, 6, 4523–4532.
  • A ternary complex of hydroxycinnamoyl-CoA hydratase-lyase (HCHL) with acetyl-CoA and vanillin gives insights into substrate specificity and mechanism.
    J P Bennett, L Bertin, B Moulton, I J S Fairlamb, A M Brzozowski, N J Walton and G Grogan, Biochem J, 2008, 414, 281-289.
  • π-Acidic alkene ligand effects in Pd-catalysed cross-coupling processes: Exploiting the interaction of dibenzylidene acetone (dba) and related ligands with Pd(0) and Pd(II).
    I J S Fairlamb, Org Biomol Chem, 2008, 6, 3645–3656.
  • Structure-activity relationships of methoxychalcones as inducers of heme oxygenase-1.
    P Sawle, B E Moulton, M Jarzykowska, C Green, R Foresti, I J S Fairlamb and R Motterlini, Chem Res Toxicol (ACS), 2008, 21, 1484-1494.
  • Synthesis and characterization of new oxazoline-based palladacycles with bridging or terminal imidato ligands. Crystal structures of [{Pd(l-dibromomaleimidate)(Phox)}2 ], [Pd(dibromomaleimidate) (Phox)(PPh3 )] and [Pd(glutarimidate)(Phox)(PPh3 )] (Phox = 2-(2-oxazolinyl)phenyl)).
    J L Serrano, L Garci, J Perez, E Perez , J Garci, G Sanchez, G Lopez, I J S Fairlamb and M Liu, Polyhedron, 2008, 27, 1699-1706.
  • Organometallic Chemistry.
    I J S Fairlamb and J M Lynam (Editors), in Organometallic Chemistry, RSC book publishing, 2008, 34, 1-450.
  • Site-selective direct arylation of unprotected adenine nucleosides mediated by palladium and copper: insights into the reaction mechanism.
    T E Storr, A G Firth, K Wilson, K Darley, C G Baumann and I J S Fairlamb, Tetrahedron, 2008, 64, 6125-6137.

2007

  • Selenium(IV)oxide.
    I J S Fairlamb, in "Encyclopedia of Reagents for Organic Synthesis", Wiley InterScience, 2007, RS008.
  • Tris(dibenzylideneacetone)dipalladium–Chloroform.
    I J S Fairlamb, in "Encyclopedia of Reagents for Organic Synthesis", Wiley InterScience, 2007, RT400.
  • A simple palladium(II) precatalyst for Suzuki-Miyaura couplings: efficient reactions of benzylic, aryl, heteroaryl and vinyl coupling partners.
    M J Burns, I J S Fairlamb, A R Kapdi, P Sehnal and R J K Taylor, Org. Lett. 2007, 9, 5397-5400.
  • Transition Metals in Organic Synthesis: Cross-coupling, C-H activation processes and cyclisation strategies.
    I J S Fairlamb, Ann Rep Sect B, 2007, 103, 68-89.
  • Kill or Cure? Carbon monoxide as a therapeutic agent.
    I J S Fairlamb and J M Lynam, Chemistry Review, 2007, April issue 16, 30-32.
  • A rationale for the linear correlation of aryl substituent effects in iron(0) tricarbonyl complexes containing α,β-unsaturated enone (chalcone) ligands
    B E Moulton, A K Duhme-Klair, I J S Fairlamb, J M Lynam and A C Whitwood, Organometallics, 2007, 26, 6354-6365.
  • In-silico prediction of Pd-catalysed cross-coupling processes: dibenzylidene acetone (dba) ligand control.
    I J S Fairlamb and A F Lee, Organometallics, 2007, 26, 4087-4089.
  • η1-2-Pyrone metal carbonyl complexes as CO-releasing molecules (CO-RMs): A delicate balance between stability and CO liberation.
    I J S Fairlamb, J M Lynam, B E Moulton, I E Taylor, A K Duhme-Klair, P Sawle and R Motterlini, Dalton Trans, 2007, 3603-3609.
  • Chiral mono- and bis-annelated cyclopentadienyl ligands derived from tartaric acid: Synthesis of [(η5-cyclopentadienyl)RuCl(cod)] and [(η5-cyclopentadienyl)(η6-benzene)Ru]PF6 derivatives.
    G P McGlacken, C T O’Brien, A C Whitwood and I J S Fairlamb, Organometallics, 2007, 26, 3722-3728.
  • Alkoxy- and amidocarbonylation of functionalised aryl and heteroaryl halides catalysed by a Bedford palladacycle and dppf: A comparison with the primary Pd(II) precursors (PhCN)2PdCl2 and Pd(OAc)2.
    I J S Fairlamb, S Grant, P McCormack and J Whittall, Dalton Trans, 2007, 859.
  • Regioselective (site-selective) functionalisation of unsaturated halogenated nitrogen, oxygen and sulfur heterocycles by Pd-catalysed cross-couplings and direct arylation processes.
    I J S Fairlamb, Chem Soc Rev, 2007, 36, 1036-1045.
  • Conformational flexibility in a carbobicyclic diphosphinite ligand.
    I J S Fairlamb, S Tommasi, B E Moulton, W Zheng, Z Lin and A C Whitwood, Eur J Inorg Chem, 2007, 3173-3178.

2006

  • The effect of the leaving ligand X on transmetallation of organostannanes (vinylSnR3) with LnPd(Ar)(X) in Stille cross-coupling reactions. A density functional theory study.
    A Ariafard, Z Lin and I J S Fairlamb, Organometallics, 2006, 25, 5788-5794
  • Phosphinite ligand effects in palladium(II)-catalysed cycloisomerisation of 1,6-dienes: Bicyclo[3.2.0]heptanyl diphosphinite (B[3.2.0]DPO) ligands exhibit flexible bite angles, an effect derived from conformational changes (exo- or endo-envelope) in the bicyclic ligand scaffold.
    I J S Fairlamb, S Grant, S Tommasi, J M Lynam, M Bandini, H Dong, Z Lin and A C Whitwood, Adv Synth Cat, 2006, 348, 2515-2530.
  • Halide and pseudohalide effects in Pd-catalysed cross-coupling reactions.
    I J S Fairlamb, R J K Taylor, J L Serrano and G Sanchez, New J Chem, 2006, 30, 1695-1704.
  • Transition Metals in Organic Synthesis: Cross-coupling and C-H activation processes.
    I J S Fairlamb, Ann Rep Pro Chem: Sect B, 2006, 102, 50-80.
  • Exploiting non-innocent (E,E)-dibenzylidene acetone (dba) effects in palladium(0) mediated cross-coupling reactions: modulation of the electronic properties of dba affects catalyst activity and stability in ligand and ligand-free reaction systems.
    I J S Fairlamb, A R Kapdi, A F Lee, G P McGlacken, F Weissburger, A H M de Vries and L Schmieder-van de Vondervoort, Chem Eur J, 2006, 12, 8750-8761.
  • Bioactive properties of iron-containing carbon monoxide-releasing molecules (CO-RMs).
    P Sawle, J Hammad, I J S Fairlamb, B E Moulton, C T O’Brien, J M Lynam, A K Duhme-Klair, R Foresti and R Motterlini, J Pharmacol Exper Ther, 2006, 318, 403-409.
  • Sonogashira alkynylation of unprotected 8-brominated adenosines and guanosines: Fluorescence properties of compact conjugated acetylenes containing a purine ring.
    A G Firth, I J S Fairlamb, K Darley and C G Baumann, Tetrahedron Lett, 2006, 47, 3529-3533.
  • Ligation-independent cloning as a rapid route to families of recombinant whole-cell biocatalysts derived from prokaryotic genome sequences.
    D Bonsor, S. F. Butz, J Solomons, S Grant, I J S Fairlamb, M J Fogg and G Grogan, Org Biomol Chem, 2006, 4, 1252-1260.
  • Influence of the dba substitution on the reactivity of Pd(0) complexes generated from Pd0 2(dba-n,n' Z)3 or Pd0(dba-n,n' Z)2 and PPh in oxidative addition with iodobenzene.
    Y Macé, A R Kapdi, I J S Fairlamb and A Jutand, Organometallics, 2006, 25, 1795-1800.
  • Regioselectivity in the Sonogashira coupling of 4,6-dichloro-2-pyrone.
    I J S Fairlamb, C T O’Brien, Z Lin and K C Lam, Org. Biomol. Chem., 2006, 4, 1213-1216.
  • Air stable, phosphine-free anionic palladacyclopentadienyl catalysts: Remarkable halide and pseudohalide effects in Stille coupling.
    C M Crawforth, I J S Fairlamb, A R Kapdi, J L Serrano, R J K Taylor and G Sanchez, Adv Synth Catal, 2006, 348, 405-412.
  • Ruthenium(II)-catalysed cycloisomerisation of 1,6-dienes by focused microwave dielectric heating: Improved rates and selectivities leading to exo-methylenecyclopentanes.
    I J S Fairlamb, G P McGlacken and F Weissberger, Chem Commun, 2006, 988-990.
  • η4-Pyrone metal carbonyl complexes as effective CO-releasing molecules (CO-RMs).
    I J S Fairlamb, A-K Duhme-Klair, J M Lynam, B E Moulton, C T O’Brien, A C Whitwood, P Sawle, J Hammad and R Motterlini, Bioorg Med Chem Lett, 2006, 16, 995-998.

2005

  • Transition metals in organic synthesis.
    I J S Fairlamb, Ann Rep Prog Chem: Sect B, 2005, 101, 69-101.
  • Synthesis of Pd(II) and Pt(II) complexes possessing bicyclo[3.2.0]heptanyl phosphinite ligands: Identification of a novel Pd(II) precatalyst for 1,6-diene cycloisomerisation.
    I J S Fairlamb, S Grant, A C Whitwood, J Whitthall, A S. Batsanov and J C. Collings, J Organomet Chem, 2005, 690, 4462.
  • Palladium catalysis in synthesis: Where next?
    I J S Fairlamb, Symposium in Print 113, Tetrahedron, 2005, 61, 9661-9662.
  • Halogenated-2-pyrones in Sonogashira cross-coupling: Limitations, optimisation and consequences for GC analysis of Pd-mediated reactions.
    I J S Fairlamb, A F Lee, F Loe-Mie, E H Niemelä, C T O’Brien and A C Whitwood, Tetrahedron, 2005, 61, 9827-9838.
  • Oxidative addition of N-halosuccinimides to palladium(0): The serendipitous discovery of neutral palladium(II) precatalysts containing imidate ligands for Stille coupling of organohalides with organostannanes.
    S Burling, C M Crawforth, I J S Fairlamb, A R Kapdi, R J K Taylor and A C Whitwood, Tetrahedron, 2005, 61, 9736-9751.
  • Optical properties of donor-acceptor phenylene-ethynylene systems containing the 6-methylpyran-2-one group as an acceptor.
    J C Collings, A C Parsons, L Porrès, A Beeby, A S Batsanov, J A K Howard, D P Lydon, P J Low, I J S Fairlamb and T B Marder, Chem Commun, 2005, 2666-2668.
  • 2-Pyrone natural products and mimetics: Isolation, characterisation and biological activity.
    G P McGlacken and I J S Fairlamb, Nat Prod Rep, 2005, 22, 369-385.
  • The requirement for an oxidant in Pd/Cu co-catalyzed terminal alkyne homocoupling to give symmetrical 1,4-disubstituted-1,3-diynes.
    J C Collings, I J S Fairlamb, J P Holland, Z Lin, T B Marder, J Zhu and R M Ward, J Org Chem, 2005, 70, 703-706.

2004

  • Transition metals in Organic Synthesis.
    I J S Fairlamb, Ann Rep Prog Chem: Sect B, 2004, 100, 113-148.
  • Ions, Radicals, Carbenes and other Monocoordinated systems
    I J S Fairlamb and J M Dickinson, "Comprehensive Organic Functional Group Transformations", 2004, Vol. II, Editors in chief: R. J. K. Taylor and A. R. Katritzky, 2004, Chapter 1.22, pp. 1177-1259.
  • η2-dba complexes of Pd(0): The substituent effect in Suzuki-Miyaura coupling.
    I J S Fairlamb, A R Kapdi and A F Lee, Org Lett, 2004, 6, 4435-4438.
  • Mono- and bidentate cyclometallated palladium(II) complexes containing bridging (N,O-) and terminal (N-) imidate ligands: Air stable, thermally robust and recyclable catalysts for cross-coupling processes.
    I J S Fairlamb, A R Kapdi, A F Lee, G Sánchez, G López, J L Serrano, L García, J Pérez and E Pérez, Dalton Trans, 2004, 3970-3981.
  • η1-Bound 2-pyrone Complexes of Molybdenum and Iron: a Synthetic and Structural Study.
    I J S Fairlamb, J M Lynam, I E Taylor and A C Whitwood, Organometallics, 2004, 21, 4964-4969.
  • Bis(triphenylphosphine)palladium(II)phthalimide – an easily prepared precatalyst for efficient Suzuki-Miyaura coupling of aryl bromides.
    N M Chaignon, I J S Fairlamb, A R Kapdi, R J K Taylor and A C Whitwood. J Mol Catal. A, 2004, 219, 191-199.
  • 2-Pyrones possessing promising antimicrobial and cytotoxic activities.
    I J S Fairlamb, L R Marrison, J M Dickinson, F-J Lu and J-P Schmidt. Bioorg Med Chem, 2004, 12, 4285-4299.
  • A one step remote hydroxylation and Baeyer-Villiger oxidation of the bicyclo[3.2.0]hept-2-en-6-one nucleus by Cunninghamella echinulata NRRL 3655.
    I J S Fairlamb, S Grant, G Grogan, D A Maddrell and J C. Nichols, Org Biomol Chem, 2004, 2, 1831-1833.
  • Palladacyclopentadiene complexes with mono- and bidendate imidato ligands: synthesis, hemilable behaviour and applications as catalysts for Stille cross-coupling reactions.
    J L Serrano, I J S Fairlamb, G Sanchez, L Garcia, J Perez, J Vives, G Lopez, C M Crawforth and R J K Taylor, Eur J Inorg Chem, 2004, 2706-2715.
  • The amazing world of transition metals in organic chemistry!
    I J S Fairlamb, Chemistry Review, 2004, May, pp. 31-32.
  • Bis(triphenylphosphine)palladium(II)succinimide as a precatalyst for Suzuki cross-coupling – Subtle effects exerted by the succinimide ligand.
    I J S Fairlamb, A R Kapdi, J M Lynam, R J K Taylor and A C Whitwood, Tetrahedron, 2004, 60, 5711-5718.
  • Isotopic desymmetrisation in the Study of Homogeneous Catalysis.
    I J S Fairlamb, G C Lloyd-Jones, A Martorell, M Murray, S C Stephen and P M Tomlin, Phosphorus, Sulfur, and Silicon and the Related Elements, 2004, 179, 907-910.
  • A new precatalyst for the Suzuki reaction – a pyridyl‑bridged dinuclear palladium complex as a source of mono-ligated palladium(0).
    A Beeby, S Bettington, I J S Fairlamb, A E Goeta, A R Kapdi and A L Thompson, New J Chem, 2004, 28, 600-605.
  • Synthesis of jaspaquinol and effect on viability of normal and malignant bladder epithelial cell lines.
    A Demotie, I J S Fairlamb, F-J Lu, N J Shaw, P A Spencer and J Southgate, Bioorg Med Chem Lett, 2004, 14, 2883-2887.
  • Unravelling the secrets of Palladium!
    I J S Fairlamb, Chemistry Review, 2004, February, pp. 2-5.
  • Important consequences for Gas Chromatographic analysis of the Sonogashira cross-coupling reaction.
    E H Niemelä, A F Lee and I J S Fairlamb, Tetrahedron Lett, 2004, 45, 3593-3595.
  • Coordination of the Trost modular ligand to palladium allyl fragments: Oligomers, monomers and memory effects in catalysis.
    G C Lloyd-Jones, S C Stephen, I J S Fairlamb, A Martorell, B Dominguez, P M Tomlin, M Murray, J M Fernandez, J C Jeffery, T Riis-Johennessen and T Guerziz, Pure Appl Chem, 2004, 76, 589-601.
  • Asymmetric cycloisomerization of 1,6- and 1,7-enynes by transition metal catalysts.
    I J S Fairlamb, Angew Chem Int Ed, 2004, 43, 1048-1052.
  • Efficient and selective Stille cross-coupling of benzylic and allylic bromides using bromobis(triphenylphosphine)(N-succinimide)palladium(II).
    C M Crawforth, I J S Fairlamb and R J K Taylor, Tetrahedron Lett, 2004, 45, 461-465.

2003

  • Bromobis(triphenylphosphine)(N-succinimide)palladium(II) as a novel catalyst for Stille cross-coupling reactions.
    C M Crawforth, S Burling, I J S Fairlamb, R J K Taylor, A C Whitwood, Chem Commun, 2003, 2194-2195.
  • Pd-catalysed cross coupling of alkynes to diynes in the absence of a stoichiometric additive.
    I J S Fairlamb, P S Bäuerlein, L R Marrison and J M Dickinson, Chem Commun, 2003, 632-633.
  • On the selective reduction of the distal olefin in geraniol and farnesol derivatives.
    A Demotie, I J S Fairlamb and S K Radford, Tetrahedron Lett, 2003, 44, 4539-4542.
  • Synthesis of (η4-(bromo)-2-pyrone-tricarbonyliron complexes.
    I J S Fairlamb, S Syvänne and A C Whitwood, Synlett, 2003, 1693-1697.
  • Pd-Catalysed alkynylation reactions of 2-pyrone (pyran-2-one) halides.
    I J S Fairlamb, F-J Lu and J-P Schmidt, Synthesis, 2003, 2564-2570.
  • Transition metals in organic synthesis: Part (i) Catalytic applications.
    I J S Fairlamb, Ann Rep Prog Chem: Sect B, 2003, 99, 104-137.
  • Transition metals in organic synthesis: Part (ii) Stoichiometric applications.
    I J S Fairlamb, Ann Rep Prog Chem: Sect B, 2003, 99, 138-160.
  • Synthesis and antimicrobial evaluation of farnesyl mimetics.
    I J S Fairlamb, J M Dickinson, R O'Connor, L H Cohen and C F van Thiel, Bioorg Chem, 2003, 31, 80-97.
  • Suzuki cross coupling approaches to the synthesis of bioactive 3-substituted and 5-substituted-4-methoxy-6-methyl-2-pyrones.
    L R Marrison, J M Dickinson and I J S Fairlamb, Bioorg Med Chem Lett, 2003, 13, 2667-2671.

2002

  • Analysis of stereochemical convergence in asymmetric Pd-catalysed allylic alkylation reactions complicated by halide and memory effects.
    I J S Fairlamb, G C Lloyd-Jones, S Vyskocil and P Kocovsky, Chem Eur J, 2002, 8, 4443-4453.
  • Cycloisomerisation of modified terpenoid 1,6-enynes – Synthesis of conformationally restricted cyclic farnesyl analogues.
    I J S Fairlamb, A C Pike and S P C P Ribrioux, Tetrahedron Lett, 2002, 43, 5327-5331.
  • Transition metals in organic synthesis: Part (i) Catalytic applications.
    I J S Fairlamb, Ann Rep Prog Chem: Sect B, 2002, 98, 123-158.
  • Transition metals in organic synthesis: Part (ii) Stoichiometric applications.
    I J S Fairlamb, Ann Rep Prog Chem: Sect B, 2002, 98, 159-189.
  • Convenient, rapid and highly regioselective cycloisomerisation of 4,4-disubstituted hepta-1,6-dienes employing neutral palladium-chloride pro-catalysts.
    K L Bray, I J S Fairlamb, J-P Kaiser, G C Lloyd-Jones and P A Slatford, Top Catal, 2002, 19, 49-59.
  • An efficient synthesis of 4-alkenyl/alkynyl-6-methyl-2-pyrones via Pd-catalysed coupling on 4-bromo-6-methyl-2-pyrone.
    L R Marrison, J M Dickinson, R Ahmed and I J S Fairlamb, Tetrahedron Lett, 2002, 43, 8853-8857.
  • Bioactive 4-substituted-6-methyl-2-pyrones with promising cytotoxicity against A2780 and K562 cell lines.
    L R Marrison, J M Dickinson and I J S Fairlamb, Bioorg Med Chem Lett, 2002, 12, 3509-3514.
  • 1,2-Bis-N-[2'-(diphenylphosphino)benzo/naphtho]-1,2-diamino-cyclohexane–Trost modular ligands.
    I J S Fairlamb, Synlett, 2002, 1176-1177.
  • Identification of new squalene synthase inhibitors using a three-dimensional pharmacophore
    I J S Fairlamb, J M Dickinson, S Higson, L G, R O'Connor and V Marin, Bioorg Med Chem, 2002, 10, 2641-2656.

2001

  • Selenium dioxide E-methyl oxidation of suitably protected geranyl derivatives – Synthesis of farnesyl mimics.
    I J S Fairlamb, J M Dickinson and M Pegg, Tetrahedron Lett, 2001, 42, 2205-2208.
  • Organometallic methods–stoichiometric transition metals.
    I J S Fairlamb and G C Lloyd-Jones, Ann Rep Prog Chem: Sect B, 2001, 97, 113-141.
  • Influence of palladium(II) complexes on the cycloaddition of a-bromoalkyl ketenes to cyclopentadiene.
    I J S Fairlamb, J M Dickinson and I M Cristea, Tetrahedron, 2001, 57, 2237-2246.
  • Halide redistribution in Pd-catalysed 1,6-diene cycloisomerisation.
    K L Bray, I J S Fairlamb, G C Lloyd-Jones, Chem Commun, 2001, 187-188.
  • Structural and mechanistic studies of the activation and propagation of a cationic allyl-Pd pro-catalyst in 1,6-diene cycloisomerisation
    K L Bray, I J S Fairlamb, J P H Charmant and G C Lloyd-Jones, Chem Eur J, 2001, 7, 4205-4215.